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Aliases for CCDC60 Gene

Aliases for CCDC60 Gene

  • Coiled-Coil Domain Containing 60 2 3 5

External Ids for CCDC60 Gene

Previous GeneCards Identifiers for CCDC60 Gene

  • GC12P118238
  • GC12P119772
  • GC12P116780

Summaries for CCDC60 Gene

GeneCards Summary for CCDC60 Gene

CCDC60 (Coiled-Coil Domain Containing 60) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC60 Gene

Genomics for CCDC60 Gene

Regulatory Elements for CCDC60 Gene

Enhancers for CCDC60 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F119207 1.2 FANTOM5 Ensembl ENCODE 1.7 -126.0 -126027 1.6 RFX1 HLF JUN CEBPB MNT REST SCRT2 HMBOX1 RCOR1 CCDC60 HSPB8 SRRM4 LOC105370026 LOC100287653
GH12F119210 0.3 FANTOM5 2 -123.8 -123755 0.3 CCDC60 LOC105370026 GC12P119226
GH12F119308 0.5 ENCODE 0.3 -25.5 -25514 0.8 SMARCA4 POLR2A PRDM1 ZBTB40 LINC00934 CCDC60
GH12F119363 0.4 ENCODE 0.3 +29.0 28969 0.2 SMARCA4 POLR2A HSPB8 LOC105370024 CCDC60 TMEM233
GH12F119413 0.6 ENCODE 0.2 +78.6 78639 0.2 CTCF ZNF654 PKNOX1 SMC3 REST PRDM1 RAD21 SRRM4 CCDC60 TMEM233
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC60 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC60 Gene

119,334,712 bp from pter
119,541,047 bp from pter
206,336 bases
Plus strand

Genomic View for CCDC60 Gene

Genes around CCDC60 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC60 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC60 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC60 Gene

Proteins for CCDC60 Gene

  • Protein details for CCDC60 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 60
    Protein Accession:

    Protein attributes for CCDC60 Gene

    550 amino acids
    Molecular mass:
    63091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC60 Gene

Post-translational modifications for CCDC60 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC60 Gene

Domains & Families for CCDC60 Gene

Protein Domains for CCDC60 Gene


Suggested Antigen Peptide Sequences for CCDC60 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC60: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC60 Gene

Function for CCDC60 Gene

Gene Ontology (GO) - Molecular Function for CCDC60 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC60: view
genes like me logo Genes that share phenotypes with CCDC60: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC60 Gene

Localization for CCDC60 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC60 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC60 Gene

Pathways & Interactions for CCDC60 Gene

SuperPathways for CCDC60 Gene

No Data Available

Interacting Proteins for CCDC60 Gene

Selected Interacting proteins: Q8IWA6-CCD60_HUMAN for CCDC60 Gene via UniProtKB IID

Gene Ontology (GO) - Biological Process for CCDC60 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC60 Gene

Transcripts for CCDC60 Gene

Unigene Clusters for CCDC60 Gene

Coiled-coil domain containing 60:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC60 Gene

No ASD Table

Relevant External Links for CCDC60 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC60 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCDC60 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC60 Gene

This gene is overexpressed in Testis (x17.6) and Bladder (x5.7).

Protein differential expression in normal tissues from HIPED for CCDC60 Gene

This gene is overexpressed in Gallbladder (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC60 Gene

Protein tissue co-expression partners for CCDC60 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC60 Gene:


SOURCE GeneReport for Unigene cluster for CCDC60 Gene:

genes like me logo Genes that share expression patterns with CCDC60: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC60 Gene

Orthologs for CCDC60 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC60 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CCDC60 34 35
  • 99.52 (n)
(Bos Taurus)
Mammalia CCDC60 34 35
  • 84.65 (n)
(Canis familiaris)
Mammalia CCDC60 34 35
  • 83.9 (n)
(Rattus norvegicus)
Mammalia Ccdc60 34
  • 78.34 (n)
(Mus musculus)
Mammalia Ccdc60 34 16 35
  • 77.76 (n)
(Monodelphis domestica)
Mammalia CCDC60 35
  • 62 (a)
(Gallus gallus)
Aves CCDC60 34 35
  • 50.17 (n)
(Anolis carolinensis)
Reptilia CCDC60 35
  • 37 (a)
Species where no ortholog for CCDC60 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC60 Gene

Gene Tree for CCDC60 (if available)
Gene Tree for CCDC60 (if available)

Paralogs for CCDC60 Gene

No data available for Paralogs for CCDC60 Gene

Variants for CCDC60 Gene

Sequence variations from dbSNP and Humsavar for CCDC60 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10219632 -- 119,535,578(+) CACAC(G/T)GCTTT intron-variant
rs10431367 -- 119,537,809(+) cgccc(A/G)cctgt intron-variant
rs10431368 -- 119,538,079(+) cagtt(C/T)gagct intron-variant
rs10534165 -- 119,350,187(+) CTTTA(-/TTAT)TTATT intron-variant
rs10544383 -- 119,377,280(+) AAAAA(A/G)AAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC60 Gene

Variant ID Type Subtype PubMed ID
dgv318e199 CNV deletion 23128226
esv2127888 CNV deletion 18987734
esv2674874 CNV deletion 23128226
esv2746459 CNV deletion 23290073
esv3407653 CNV duplication 20981092
esv3549870 CNV deletion 23714750
esv3549871 CNV deletion 23714750
esv3630902 CNV loss 21293372
esv3817 CNV loss 18987735
esv7481 CNV loss 19470904
nsv1035871 CNV gain 25217958
nsv474516 CNV novel sequence insertion 20440878
nsv832528 CNV gain 17160897
nsv832529 CNV loss 17160897

Variation tolerance for CCDC60 Gene

Residual Variation Intolerance Score: 97.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.15; 84.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC60 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC60 Gene

Disorders for CCDC60 Gene

Relevant External Links for CCDC60

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC60 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC60 Gene

Publications for CCDC60 Gene

  1. A genome-wide association study in 574 schizophrenia trios using DNA pooling. (PMID: 18332876) Kirov G. … O'Donovan M.C. (Mol. Psychiatry 2009) 3 46 64
  2. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. (PMID: 17903295) Lunetta K.L. … Murabito J.M. (BMC Med. Genet. 2007) 3 46 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for CCDC60 Gene

Sources for CCDC60 Gene

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