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Aliases for CCDC51 Gene

Aliases for CCDC51 Gene

  • Coiled-Coil Domain Containing 51 2 3 5

External Ids for CCDC51 Gene

Previous GeneCards Identifiers for CCDC51 Gene

  • GC03M048450
  • GC03M048473

Summaries for CCDC51 Gene

GeneCards Summary for CCDC51 Gene

CCDC51 (Coiled-Coil Domain Containing 51) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC51 Gene

Genomics for CCDC51 Gene

Regulatory Elements for CCDC51 Gene

Promoters for CCDC51 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC51 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC51 Gene

Chromosome:
3
Start:
48,432,164 bp from pter
End:
48,441,078 bp from pter
Size:
8,915 bases
Orientation:
Minus strand

Genomic View for CCDC51 Gene

Genes around CCDC51 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC51 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC51 Gene

Proteins for CCDC51 Gene

  • Protein details for CCDC51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96ER9-CCD51_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 51
    Protein Accession:
    Q96ER9
    Secondary Accessions:
    • Q9HA01

    Protein attributes for CCDC51 Gene

    Size:
    411 amino acids
    Molecular mass:
    45811 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH11993.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC51 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC51 Gene

Proteomics data for CCDC51 Gene at MOPED

Post-translational modifications for CCDC51 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC51 Gene

Domains & Families for CCDC51 Gene

Protein Domains for CCDC51 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC51 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC51: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC51 Gene

Function for CCDC51 Gene

genes like me logo Genes that share phenotypes with CCDC51: view

Animal Model Products

miRNA for CCDC51 Gene

miRTarBase miRNAs that target CCDC51

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC51 Gene

Localization for CCDC51 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC51 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC51 Gene COMPARTMENTS Subcellular localization image for CCDC51 gene
Compartment Confidence
mitochondrion 5
nucleus 5
cytosol 1
extracellular 1
lysosome 1
plasma membrane 1
vacuole 1

Gene Ontology (GO) - Cellular Components for CCDC51 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005739 mitochondrion IDA --
genes like me logo Genes that share ontologies with CCDC51: view

Pathways & Interactions for CCDC51 Gene

SuperPathways for CCDC51 Gene

No Data Available

Interacting Proteins for CCDC51 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000379047%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000379047 for CCDC51 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CCDC51 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC51 Gene

Drugs & Compounds for CCDC51 Gene

No Compound Related Data Available

Transcripts for CCDC51 Gene

Unigene Clusters for CCDC51 Gene

Coiled-coil domain containing 51:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC51 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1: - -
SP2: - -
SP3: - - -
SP4: - - -
SP5: -
SP6: - - -

Relevant External Links for CCDC51 Gene

GeneLoc Exon Structure for
CCDC51
ECgene alternative splicing isoforms for
CCDC51

Expression for CCDC51 Gene

mRNA expression in normal human tissues for CCDC51 Gene

Protein differential expression in normal tissues from HIPED for CCDC51 Gene

This gene is overexpressed in Urine (9.5) and Bone (8.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CCDC51 Gene



SOURCE GeneReport for Unigene cluster for CCDC51 Gene Hs.187657

genes like me logo Genes that share expression patterns with CCDC51: view

Protein tissue co-expression partners for CCDC51 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC51 Gene

Orthologs for CCDC51 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC51 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC51 36
  • 100 (a)
OneToOne
CCDC51 35
  • 99.59 (n)
  • 99.51 (a)
cow
(Bos Taurus)
Mammalia CCDC51 35
  • 85.97 (n)
  • 86.14 (a)
CCDC51 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC51 36
  • 88 (a)
OneToOne
CCDC51 35
  • 87.97 (n)
  • 88.29 (a)
mouse
(Mus musculus)
Mammalia Ccdc51 16
Ccdc51 36
  • 82 (a)
OneToOne
Ccdc51 35
  • 82.76 (n)
  • 82.27 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC51 36
  • 63 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC51 36
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc51 35
  • 83.2 (n)
  • 84.43 (a)
chicken
(Gallus gallus)
Aves CCDC51 35
  • 63.07 (n)
  • 58.95 (a)
CCDC51 36
  • 54 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC51 36
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc51 35
  • 59.28 (n)
  • 56.46 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7497 35
zebrafish
(Danio rerio)
Actinopterygii ccdc51 36
  • 46 (a)
OneToOne
ccdc51 35
  • 55.75 (n)
  • 54.6 (a)
Dr.6242 35
worm
(Caenorhabditis elegans)
Secernentea ZC477.3 35
  • 45.02 (n)
  • 34.71 (a)
ZC477.3 36
  • 30 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
OneToOne
Species with no ortholog for CCDC51:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC51 Gene

ENSEMBL:
Gene Tree for CCDC51 (if available)
TreeFam:
Gene Tree for CCDC51 (if available)

Paralogs for CCDC51 Gene

No data available for Paralogs for CCDC51 Gene

Variants for CCDC51 Gene

Sequence variations from dbSNP and Humsavar for CCDC51 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
VAR_032515 -
rs1109227 -- 48,437,797(+) AACCA(C/T)CAGTA intron-variant
rs1459249 -- 48,438,208(+) aatgg(C/T)caaaa intron-variant
rs2015671 -- 48,435,926(-) TGAGC(A/G)ATGGC intron-variant
rs2015713 -- 48,435,443(+) TCCAG(C/G)TCTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC51 Gene

Variant ID Type Subtype PubMed ID
nsv834683 CNV Gain 17160897
nsv834684 CNV Gain 17160897
nsv508917 CNV Insertion 20534489
nsv876761 CNV Loss 21882294

Variation tolerance for CCDC51 Gene

Residual Variation Intolerance Score: 78.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.80; 47.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC51 Gene

HapMap Linkage Disequilibrium report
CCDC51

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC51 Gene

Disorders for CCDC51 Gene

Relevant External Links for CCDC51

Genetic Association Database (GAD)
CCDC51
Human Genome Epidemiology (HuGE) Navigator
CCDC51
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC51

No disorders were found for CCDC51 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC51 Gene

Publications for CCDC51 Gene

  1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for CCDC51 Gene

Sources for CCDC51 Gene

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