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Aliases for CCDC47 Gene

Aliases for CCDC47 Gene

  • Coiled-Coil Domain Containing 47 2 3 5
  • MSTP041 3
  • GK001 3

External Ids for CCDC47 Gene

Previous GeneCards Identifiers for CCDC47 Gene

  • GC17M059177
  • GC17M061822
  • GC17M057190

Summaries for CCDC47 Gene

GeneCards Summary for CCDC47 Gene

CCDC47 (Coiled-Coil Domain Containing 47) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding and calcium ion binding. An important paralog of this gene is ENSG00000125695.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC47 Gene

Genomics for CCDC47 Gene

Regulatory Elements for CCDC47 Gene

Enhancers for CCDC47 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC47 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC47 Gene

Chromosome:
17
Start:
63,745,250 bp from pter
End:
63,776,351 bp from pter
Size:
31,102 bases
Orientation:
Minus strand

Genomic View for CCDC47 Gene

Genes around CCDC47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC47 Gene

Proteins for CCDC47 Gene

  • Protein details for CCDC47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96A33-CCD47_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 47
    Protein Accession:
    Q96A33
    Secondary Accessions:
    • B2RAS8
    • D3DU20
    • Q96D00
    • Q96JZ7
    • Q9H3E4
    • Q9NRG3

    Protein attributes for CCDC47 Gene

    Size:
    483 amino acids
    Molecular mass:
    55874 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAG39292.1; Type=Frameshift; Positions=306; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC47 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC47 Gene

Proteomics data for CCDC47 Gene at MOPED

Post-translational modifications for CCDC47 Gene

Other Protein References for CCDC47 Gene

No data available for DME Specific Peptides for CCDC47 Gene

Domains & Families for CCDC47 Gene

Protein Domains for CCDC47 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC47 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC47: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC47 Gene

Function for CCDC47 Gene

Phenotypes for CCDC47 Gene

MGI mutant phenotypes for CCDC47:
inferred from 1 alleles
GenomeRNAi human phenotypes for CCDC47:
genes like me logo Genes that share phenotypes with CCDC47: view

Animal Models for CCDC47 Gene

MGI Knock Outs for CCDC47:

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCDC47 Gene

Localization for CCDC47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC47 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC47 Gene COMPARTMENTS Subcellular localization image for CCDC47 gene
Compartment Confidence
endoplasmic reticulum 5
cytosol 1
extracellular 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for CCDC47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CCDC47: view

Pathways & Interactions for CCDC47 Gene

SuperPathways for CCDC47 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0055074 calcium ion homeostasis IEA --
genes like me logo Genes that share ontologies with CCDC47: view

No data available for Pathways by source and SIGNOR curated interactions for CCDC47 Gene

Drugs & Compounds for CCDC47 Gene

No Compound Related Data Available

Transcripts for CCDC47 Gene

mRNA/cDNA for CCDC47 Gene

(2) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC47 Gene

Coiled-coil domain containing 47:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC47 Gene

No ASD Table

Relevant External Links for CCDC47 Gene

GeneLoc Exon Structure for
CCDC47
ECgene alternative splicing isoforms for
CCDC47

Expression for CCDC47 Gene

mRNA expression in normal human tissues for CCDC47 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC47 Gene

This gene is overexpressed in Pancreas (10.9) and Nasal epithelium (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC47 Gene



SOURCE GeneReport for Unigene cluster for CCDC47 Gene Hs.202011

genes like me logo Genes that share expression patterns with CCDC47: view

Protein tissue co-expression partners for CCDC47 Gene

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC47 Gene

Orthologs for CCDC47 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CCDC47 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CCDC47 35
  • 93.51 (n)
  • 97.93 (a)
CCDC47 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC47 35
  • 94.69 (n)
  • 98.76 (a)
CCDC47 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc47 35
  • 92.13 (n)
  • 97.93 (a)
Ccdc47 16
Ccdc47 36
  • 98 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CCDC47 35
  • 99.93 (n)
  • 100 (a)
CCDC47 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc47 35
  • 91.65 (n)
  • 97.93 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC47 36
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC47 36
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC47 35
  • 81.84 (n)
  • 89.81 (a)
CCDC47 36
  • 90 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC47 36
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc47 35
  • 79.21 (n)
  • 90.32 (a)
Str.586 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.16389 35
zebrafish
(Danio rerio)
Actinopterygii ccdc47 35
  • 74.34 (n)
  • 80.86 (a)
wufd13e11 35
ccdc47 36
  • 77 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1555 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010007 35
  • 51.96 (n)
  • 46.24 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG17593 35
  • 50.95 (n)
  • 45.81 (a)
CG17593 36
  • 45 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ccdc-47 35
  • 50.36 (n)
  • 38.69 (a)
ccdc-47 36
  • 39 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G24330 35
  • 45.59 (n)
  • 34.37 (a)
rice
(Oryza sativa)
Liliopsida Os05g0432400 35
  • 44.81 (n)
  • 32.94 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1616 36
  • 47 (a)
OneToMany
Species with no ortholog for CCDC47:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC47 Gene

ENSEMBL:
Gene Tree for CCDC47 (if available)
TreeFam:
Gene Tree for CCDC47 (if available)

Paralogs for CCDC47 Gene

Paralogs for CCDC47 Gene

genes like me logo Genes that share paralogs with CCDC47: view

Variants for CCDC47 Gene

Sequence variations from dbSNP and Humsavar for CCDC47 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs9207 -- 63,746,539(+) TTTCA(C/T)GGTAT utr-variant-3-prime
rs14954 -- 63,746,557(+) AACAC(A/T)GAAGT utr-variant-3-prime
rs1272676 -- 63,751,512(-) TTACC(C/T)AACTA intron-variant
rs2044124 -- 63,768,065(+) AAAAC(C/T)ACCAG intron-variant
rs4078471 -- 63,748,941(-) cgcct(A/C)ccagg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC47 Gene

Variant ID Type Subtype PubMed ID
esv2266185 CNV Deletion 18987734
nsv833510 CNV Loss 17160897

Variation tolerance for CCDC47 Gene

Residual Variation Intolerance Score: 14.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.02; 20.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC47 Gene

Human Gene Mutation Database (HGMD)
CCDC47

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC47 Gene

Disorders for CCDC47 Gene

Relevant External Links for CCDC47

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC47

No disorders were found for CCDC47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC47 Gene

Publications for CCDC47 Gene

  1. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. (PMID: 25852190) So J. … Colwill K. (Sci Signal 2015) 3
  4. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3
  5. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3

Products for CCDC47 Gene

Sources for CCDC47 Gene

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