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Aliases for CCDC43 Gene

Aliases for CCDC43 Gene

  • Coiled-Coil Domain Containing 43 2 3

External Ids for CCDC43 Gene

Previous GeneCards Identifiers for CCDC43 Gene

  • GC17M040112
  • GC17M042754
  • GC17M038519

Summaries for CCDC43 Gene

GeneCards Summary for CCDC43 Gene

CCDC43 (Coiled-Coil Domain Containing 43) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC43 Gene

Genomics for CCDC43 Gene

Regulatory Elements for CCDC43 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC43 Gene

44,673,069 bp from pter
44,689,797 bp from pter
16,729 bases
Minus strand

Genomic View for CCDC43 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC43 Gene

Proteins for CCDC43 Gene

  • Protein details for CCDC43 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 43
    Protein Accession:
    Secondary Accessions:
    • C9JVK9

    Protein attributes for CCDC43 Gene

    224 amino acids
    Molecular mass:
    25248 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC43 Gene


neXtProt entry for CCDC43 Gene

Proteomics data for CCDC43 Gene at MOPED

Post-translational modifications for CCDC43 Gene

  • Ubiquitination at Lys162
  • Modification sites at PhosphoSitePlus

Other Protein References for CCDC43 Gene

No data available for DME Specific Peptides for CCDC43 Gene

Domains for CCDC43 Gene

Protein Domains for CCDC43 Gene


Suggested Antigen Peptide Sequences for CCDC43 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q96MW1
  • Belongs to the CCDC43 family.
genes like me logo Genes that share domains with CCDC43: view

No data available for Gene Families for CCDC43 Gene

Function for CCDC43 Gene

Gene Ontology (GO) - Molecular Function for CCDC43 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC43: view

Animal Model Products

miRNA for CCDC43 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC43

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC43 Gene

Localization for CCDC43 Gene

Subcellular locations from

Jensen Localization Image for CCDC43 Gene COMPARTMENTS Subcellular localization image for CCDC43 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC43 Gene

Pathways for CCDC43 Gene

SuperPathways for CCDC43 Gene

No Data Available

Interacting Proteins for CCDC43 Gene

Gene Ontology (GO) - Biological Process for CCDC43 Gene


No data available for Pathways by source for CCDC43 Gene

Transcripts for CCDC43 Gene

Unigene Clusters for CCDC43 Gene

Coiled-coil domain containing 43:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC43

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC43 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b
SP1: - -
SP2: -

Relevant External Links for CCDC43 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC43 Gene

mRNA expression in normal human tissues for CCDC43 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC43 Gene

This gene is overexpressed in Muscle - Skeletal (4.8).

Protein differential expression in normal tissues for CCDC43 Gene

This gene is overexpressed in Bone marrow stromal cell (7.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC43 Gene

SOURCE GeneReport for Unigene cluster for CCDC43 Gene Hs.579115

genes like me logo Genes that share expressions with CCDC43: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for CCDC43 Gene

Orthologs for CCDC43 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC43 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC43 35
  • 92.42 (n)
  • 96.68 (a)
CCDC43 36
  • 95 (a)
(Canis familiaris)
Mammalia CCDC43 35
  • 92.11 (n)
  • 95.98 (a)
CCDC43 36
  • 96 (a)
(Mus musculus)
Mammalia Ccdc43 35
  • 85.74 (n)
  • 89.19 (a)
Ccdc43 16
Ccdc43 36
  • 90 (a)
(Pan troglodytes)
Mammalia CCDC43 35
  • 99.7 (n)
  • 99.11 (a)
CCDC43 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc43 35
  • 86.19 (n)
  • 90.99 (a)
(Monodelphis domestica)
Mammalia CCDC43 36
  • 85 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC43 36
  • 64 (a)
(Gallus gallus)
Aves CCDC43 35
  • 73.77 (n)
  • 73.15 (a)
CCDC43 36
  • 74 (a)
(Anolis carolinensis)
Reptilia CCDC43 36
  • 66 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc43 35
  • 68.87 (n)
  • 66.04 (a)
(Danio rerio)
Actinopterygii -- 35
ccdc43 35
  • 68.41 (n)
  • 64.29 (a)
ccdc43 36
  • 63 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009665 35
  • 48.87 (n)
  • 42.93 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9586 35
  • 43.76 (n)
  • 36.41 (a)
CG9586 36
  • 32 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3227 36
  • 28 (a)
Species with no ortholog for CCDC43:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC43 Gene

Gene Tree for CCDC43 (if available)
Gene Tree for CCDC43 (if available)

Paralogs for CCDC43 Gene

No data available for Paralogs for CCDC43 Gene

Variants for CCDC43 Gene

Sequence variations from dbSNP and Humsavar for CCDC43 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs4793140 -- 44,685,234(+) TTCCC(A/T)AAGTC intron-variant
rs7222082 -- 44,678,604(+) ACTTG(A/G)GTATT utr-variant-3-prime
rs7502911 -- 44,682,986(+) cagga(G/T)ctttt intron-variant
rs8072000 -- 44,686,213(+) CAGCC(A/G)AGCCC intron-variant
rs8079825 -- 44,682,868(+) AAAAA(A/T)ATTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC43 Gene

Variant ID Type Subtype PubMed ID
nsv908286 CNV Loss 21882294
nsv833456 CNV Gain+Loss 17160897
nsv908287 CNV Loss 21882294
nsv112452 CNV Loss 16902084

Relevant External Links for CCDC43 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC43 Gene

Disorders for CCDC43 Gene

No disorders were found for CCDC43 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CCDC43 Gene

Publications for CCDC43 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PMID: 21044950) Lee O.H. … Songyang Z. (Mol. Cell Proteomics 2011) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for CCDC43 Gene

Sources for CCDC43 Gene

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