CCDC42B Gene
protein-coding GIFtS: 34
GCID: GC12P113587
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coiled-coil domain containing 42B
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Aliases
for CCDC42B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 42B1 2 | | Coiled-Coil Domain-Containing Protein 42B2 |
Export aliases for CCDC42B gene to outside databasesPrevious GC identifers: GC12P112074 GC12P110600 |
Summaries
for CCDC42B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC42B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009775.17
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for CCDC42B
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC42B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC42B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.13 Ensembl cytogenetic band: 12q24.13 HGNC cytogenetic band: 12q24.13CCDC42B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P113587: view genomic region
(about GC identifiers)
Start:
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113,587,663 bp from pter |
End:
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113,597,081 bp from pter |
Size:
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9,419 bases |
Orientation:
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plus strand |
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Proteins
for CCDC42B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC42B_HUMAN, A6NFT4 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 42B Size: 308 amino acids; 35914 DaExplore the universe of human proteins at neXtProt for CCDC42B: NX_A6NFT4
CCDC42B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001138344.1
ENSEMBL proteins: ENSP00000333915 ENSP00000447276
Human Recombinant Protein Products:
CCDC42B Antibody Products:
Assay Products for CCDC42B: |
Protein
Domains /
Families
for CCDC42B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCDC42B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry A6NFT4ProtoNet protein and cluster: A6NFT4 UniProtKB/Swiss-Prot: CC42B_HUMAN, A6NFT4Similarity: Belongs to the CCDC42 family |
Function
for CCDC42B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC42B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC42B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC42B (NM_001144872) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC42B | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CCDC42B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC42B |
|
Pathways & Interactions
for CCDC42B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC42B
|
Drugs & Compounds
for CCDC42B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC42B
Search CenterWatch for drugs/clinical trials and news about CCDC42B / CC42B
|
Transcripts
for CCDC42B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC42B gene: NM_001144872.1 Unigene Cluster for CCDC42B: Coiled-coil domain containing 42B Hs.486856 [show with all ESTs]Unigene Representative Sequence: NM_0011448723 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000335621(uc010sys.2) ENST00000551256 ENST00000550918
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC42B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC42B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC42B (NM_001144872) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC42B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CCDC42B |
Additional cDNA sequence: AK308987.1 9 DOTS entries: DT.40131798 DT.92001434 DT.99968102 DT.95151690 DT.444686 DT.121121585 DT.121121652 DT.100817287 DT.121121638 24/26 AceView cDNA sequences (see all 26): AI811792 AW406211 AA292172 BQ049226 BM975869 AW166237 BE270874 BM975359 AA552350 AA913370 R50289 T91897 AA810999 AI859126 H25463 BE241450 Z25175 BE267553 H03116 N28719 AI933990 AI126158 AI394365 AW166470
GeneLoc Exon Structure
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Expression
for CCDC42B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC42B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGCCGGCC
About this image
See CCDC42B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC42B
SOURCE GeneReport for Unigene cluster: Hs.486856
SABiosciences Custom PCR Arrays for CCDC42B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC42B
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CCDC42B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC42B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC42B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC42B |
Orthologs
for CCDC42B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CCDC42B gene from 5/17 species (see all 17) About this table
ENSEMBL Gene Tree for CCDC42B (if available)
TreeFam Gene Tree for CCDC42B (if available) |
Paralogs
for CCDC42B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCDC42B gene
- CCDC422
1 SIMAP similar gene for CCDC42B using alignment to 2 protein entries: CC42B_HUMAN (see all proteins):CCDC42
CCDC42B for paralogs About GeneDecksing
|
Genomic Variants
for CCDC42B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for CCDC42B (113587663 - 113597081 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CCDC42B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC42B |
|
Disorders
/ Diseases
for CCDC42B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CCDC42B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed article for CCDC42B gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC42B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The finished DNA sequence of human chromosome 12. (PubMed id 16541075)1, 2 Scherer S.E.... Gibbs R.A. (2006)
|
External Searches for CCDC42B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing CCDC42B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC42B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC42B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC42B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC42B gene:
Search GeneIP for patents involving CCDC42B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC42B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC42B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC42B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC42B | | | OriGene Protein Over-expression Lysate for CCDC42B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC42B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC42B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC42B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC42B | | OriGene Custom Protein Services for CCDC42B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC42B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC42B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC42B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC42B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC42B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC42B |
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 |  |  |  | |
| | | | Search Tocris compounds for CCDC42B |
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 | | | CCDC42B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC42B |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC42B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CCDC42B |
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