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Aliases for CCDC42B Gene

Aliases for CCDC42B Gene

  • Coiled-Coil Domain Containing 42B 2 3
  • Coiled-Coil Domain-Containing Protein 42B 3
  • MIA2 3

External Ids for CCDC42B Gene

Summaries for CCDC42B Gene

GeneCards Summary for CCDC42B Gene

CCDC42B (Coiled-Coil Domain Containing 42B) is a Protein Coding gene. An important paralog of this gene is CCDC42.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC42B Gene

Genomics for CCDC42B Gene

Genomic Location for CCDC42B Gene

Start:
113,149,738 bp from pter
End:
113,159,276 bp from pter
Size:
9,539 bases
Orientation:
Plus strand

Genomic View for CCDC42B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC42B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC42B Gene

No data available for Regulatory Elements for CCDC42B Gene

Proteins for CCDC42B Gene

  • Protein details for CCDC42B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFT4-CC42B_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 42B
    Protein Accession:
    A6NFT4
    Secondary Accessions:

    Protein attributes for CCDC42B Gene

    Size:
    308 amino acids
    Molecular mass:
    35914 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC42B Gene

Proteomics data for CCDC42B Gene at MOPED

Post-translational modifications for CCDC42B Gene

No Post-translational modifications

Other Protein References for CCDC42B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC42B Gene

Domains for CCDC42B Gene

Protein Domains for CCDC42B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC42B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NFT4

UniProtKB/Swiss-Prot:

CC42B_HUMAN
Family:
  • Belongs to the CCDC42 family.:
    • A6NFT4
genes like me logo Genes that share domains with CCDC42B: view

No data available for Gene Families for CCDC42B Gene

Function for CCDC42B Gene

miRNA for CCDC42B Gene

miRTarBase miRNAs that target CCDC42B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC42B Gene

Localization for CCDC42B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC42B Gene COMPARTMENTS Subcellular localization image for CCDC42B gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC42B Gene

Pathways for CCDC42B Gene

SuperPathways for CCDC42B Gene

No Data Available

Interacting Proteins for CCDC42B Gene

Gene Ontology (GO) - Biological Process for CCDC42B Gene

None

No data available for Pathways by source for CCDC42B Gene

Transcripts for CCDC42B Gene

mRNA/cDNA for CCDC42B Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(26) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC42B Gene

Coiled-coil domain containing 42B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC42B Gene

No ASD Table

Relevant External Links for CCDC42B Gene

GeneLoc Exon Structure for
CCDC42B
ECgene alternative splicing isoforms for
CCDC42B

Expression for CCDC42B Gene

mRNA expression in normal human tissues for CCDC42B Gene

mRNA differential expression in normal tissues according to GTEx for CCDC42B Gene

This gene is overexpressed in Fallopian Tube (14.6), Cervix - Endocervix (6.6), Brain - Caudate (basal ganglia) (5.8), Brain - Hypothalamus (5.2), and Lung (4.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC42B Gene

SOURCE GeneReport for Unigene cluster for CCDC42B Gene Hs.486856

genes like me logo Genes that share expressions with CCDC42B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC42B Gene

Orthologs for CCDC42B Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC42B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC42B 35
  • 99.57 (n)
  • 99.35 (a)
CCDC42B 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC42B 35
  • 83.12 (n)
  • 80.19 (a)
CCDC42B 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC42B 35
  • 82.44 (n)
  • 75.5 (a)
CCDC42B 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc42b 35
  • 67.97 (n)
  • 53.92 (a)
Ccdc42b 16
Ccdc42b 36
  • 54 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC42B 36
  • 38 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc42b 35
  • 68.87 (n)
  • 52.81 (a)
chicken
(Gallus gallus)
Aves CCDC42B 35
  • 55.21 (n)
  • 41.7 (a)
CCDC42B 36
  • 38 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC42B 36
  • 39 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ccdc42b 36
  • 27 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4208 36
  • 39 (a)
OneToMany
Species with no ortholog for CCDC42B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC42B Gene

ENSEMBL:
Gene Tree for CCDC42B (if available)
TreeFam:
Gene Tree for CCDC42B (if available)

Paralogs for CCDC42B Gene

Paralogs for CCDC42B Gene

Selected SIMAP similar genes for CCDC42B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC42B: view

Variants for CCDC42B Gene

Sequence variations from dbSNP and Humsavar for CCDC42B Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs4356292 -- 113,153,337(+) CGCGG(C/G)TGCAG reference, missense
rs7136744 -- 113,151,096(+) GGAAC(A/G)GGGAT intron-variant
rs7307978 -- 113,154,134(+) attag(C/T)cgggc intron-variant
rs7959803 -- 113,150,326(+) TTTCT(C/T)CTGGA intron-variant
rs11066500 -- 113,149,765(+) GCAGG(C/T)TTCCA upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for CCDC42B Gene

Variant ID Type Subtype PubMed ID
nsv519540 CNV Gain+Loss 19592680
nsv899527 CNV Loss 21882294
nsv899528 CNV Loss 21882294
nsv899530 CNV Gain 21882294

Relevant External Links for CCDC42B Gene

HapMap Linkage Disequilibrium report
CCDC42B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC42B Gene

Disorders for CCDC42B Gene

No disorders were found for CCDC42B Gene.

No data available for UniProtKB/Swiss-Prot for CCDC42B Gene

Publications for CCDC42B Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4
  2. The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility. (PMID: 23569216) Yamamoto R. … Sale W.S. (J. Cell Biol. 2013) 2 3

Products for CCDC42B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate CCDC42B
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC42B
  • Block miRNA regulation of CCDC42B using miScript Target Protectors

Sources for CCDC42B Gene

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