Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CCDC42 Gene

Aliases for CCDC42 Gene

  • Coiled-Coil Domain Containing 42 2 3
  • CCDC42A 3 4
  • Coiled-Coil Domain-Containing Protein 42A 3

External Ids for CCDC42 Gene

Previous GeneCards Identifiers for CCDC42 Gene

  • GC17M008575

Summaries for CCDC42 Gene

GeneCards Summary for CCDC42 Gene

CCDC42 (Coiled-Coil Domain Containing 42) is a Protein Coding gene. An important paralog of this gene is CCDC42B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC42 Gene

Genomics for CCDC42 Gene

Regulatory Elements for CCDC42 Gene

Genomic Location for CCDC42 Gene

Start:
8,729,928 bp from pter
End:
8,746,002 bp from pter
Size:
16,075 bases
Orientation:
Minus strand

Genomic View for CCDC42 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC42 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC42 Gene

Proteins for CCDC42 Gene

  • Protein details for CCDC42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96M95-CCD42_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 42A
    Protein Accession:
    Q96M95
    Secondary Accessions:
    • Q8N6Q0

    Protein attributes for CCDC42 Gene

    Size:
    316 amino acids
    Molecular mass:
    38019 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC42 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC42 Gene

Proteomics data for CCDC42 Gene at MOPED

Post-translational modifications for CCDC42 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC42 Gene

No data available for DME Specific Peptides for CCDC42 Gene

Domains for CCDC42 Gene

Protein Domains for CCDC42 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC42 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96M95

UniProtKB/Swiss-Prot:

CCD42_HUMAN :
  • Q96M95
Family:
  • Belongs to the CCDC42 family.
genes like me logo Genes that share domains with CCDC42: view

No data available for Gene Families for CCDC42 Gene

Function for CCDC42 Gene

Gene Ontology (GO) - Molecular Function for CCDC42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC42: view

Phenotypes for CCDC42 Gene

GenomeRNAi human phenotypes for CCDC42:
genes like me logo Genes that share phenotypes with CCDC42: view

Animal Model Products

CRISPR Products

miRNA for CCDC42 Gene

miRTarBase miRNAs that target CCDC42

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC42

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC42 Gene

Localization for CCDC42 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC42 Gene COMPARTMENTS Subcellular localization image for CCDC42 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC42 Gene

Pathways for CCDC42 Gene

SuperPathways for CCDC42 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC42 Gene

None

No data available for Pathways by source for CCDC42 Gene

Transcripts for CCDC42 Gene

mRNA/cDNA for CCDC42 Gene

Unigene Clusters for CCDC42 Gene

Coiled-coil domain containing 42:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC42

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC42 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
SP1:
SP2: -
SP3: -

Relevant External Links for CCDC42 Gene

GeneLoc Exon Structure for
CCDC42
ECgene alternative splicing isoforms for
CCDC42

Expression for CCDC42 Gene

mRNA expression in normal human tissues for CCDC42 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC42 Gene

This gene is overexpressed in Testis (50.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC42 Gene

SOURCE GeneReport for Unigene cluster for CCDC42 Gene Hs.121438

genes like me logo Genes that share expressions with CCDC42: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC42 Gene

Orthologs for CCDC42 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC42 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC42 35
  • 99.58 (n)
  • 99.37 (a)
CCDC42 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC42 35
  • 88.08 (n)
  • 86.39 (a)
CCDC42 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC42 35
  • 86.6 (n)
  • 85.76 (a)
CCDC42 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc42 35
  • 84.92 (n)
  • 86.39 (a)
Ccdc42 16
Ccdc42 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC42 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc42 35
  • 84.07 (n)
  • 85.44 (a)
chicken
(Gallus gallus)
Aves CCDC42 35
  • 62.87 (n)
  • 49.51 (a)
CCDC42 36
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC42 36
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100145050 35
  • 52.93 (n)
  • 41.22 (a)
zebrafish
(Danio rerio)
Actinopterygii ccdc42b 36
  • 30 (a)
OneToMany
LOC100001777 35
  • 50.59 (n)
  • 33.17 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4208 36
  • 46 (a)
OneToMany
Species with no ortholog for CCDC42:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC42 Gene

ENSEMBL:
Gene Tree for CCDC42 (if available)
TreeFam:
Gene Tree for CCDC42 (if available)

Paralogs for CCDC42 Gene

Paralogs for CCDC42 Gene

Selected SIMAP similar genes for CCDC42 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC42: view

Variants for CCDC42 Gene

Sequence variations from dbSNP and Humsavar for CCDC42 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs169070 -- 8,731,183(-) cattA(A/G)AACTG intron-variant
rs187830 -- 8,740,645(-) CCCCT(C/T)TGCCC intron-variant
rs192355 -- 8,731,085(-) CCCCA(A/C/G)ACCTG intron-variant
rs197077 -- 8,729,861(+) TTTGA(A/G)AGTGA downstream-variant-500B
rs373731 -- 8,731,169(-) TCTTA(A/G)AGGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC42 Gene

Variant ID Type Subtype PubMed ID
nsv518675 CNV Gain 19592680
nsv907667 CNV Gain 21882294
nsv907668 CNV Loss 21882294

Relevant External Links for CCDC42 Gene

HapMap Linkage Disequilibrium report
CCDC42

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC42 Gene

Disorders for CCDC42 Gene

Relevant External Links for CCDC42

Genetic Association Database (GAD)
CCDC42
genes like me logo Genes that share disorders with CCDC42: view

No data available for UniProtKB/Swiss-Prot for CCDC42 Gene

Publications for CCDC42 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Human ORFeome version 1.1: a platform for reverse proteomics. (PMID: 15489335) Rual J.F. … Vidal M. (Genome Res. 2004) 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for CCDC42 Gene

Sources for CCDC42 Gene

Back to Top

Content