CCDC41 Gene
protein-coding GIFtS : 40
GCID: GC12 M094702
coiled-coil domain containing 41
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Aliasesfor CCDC41 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Coiled-Coil Domain Containing 41 1 2 NY-REN-581 2 Renal Carcinoma Antigen NY-REN-582 3 Coiled-Coil Domain-Containing Protein 412 NY-REN-58 Antigen2
Export aliases for CCDC41 gene to outside databases Previous GC identifers: GC12M093205 GC12M091769
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Summariesfor CCDC41 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor CCDC41 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000012.11 NC_018923.1 NT_029419.12 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CCDC41 gene promoter: STAT1 STAT4 STAT1beta RelA CUTL1 NF-kappaB STAT1alpha STAT2 STAT3 NF-kappaB1 Other transcription factors Search SABiosciences Chromatin IP Primers for CCDC41 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat CCDC41
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 12q22 Ensembl cytogenetic band: 12q22 HGNC cytogenetic band: 12q22 CCDC41 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 12 GeneLoc Exon Structure
GeneLoc location for GC12M094702: view genomic region
(about GC identifiers )
Start:
94,700,225 bp from pter
End:
94,853,764 bp from pter
Size:
153,540 bases
Orientation:
minus strand
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Proteinsfor CCDC41 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: CCD41_HUMAN, Q9Y592 (See
protein sequence )Recommended Name: Coiled-coil domain-containing protein 41 Size : 693 amino acids; 82059 Da
Sequence caution : Sequence=AAD42881.1; Type=Frameshift; Positions=105, 590, 601;
Secondary accessions : A4FVB1 Q08AP1Alternative splicing : 2 isoforms : Q9Y592-1 Q9Y592-2 Explore the universe of human proteins at neXtProt for CCDC41: NX_Q9Y592 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9Y592 CCDC41 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (2 alternative transcripts):
NP_001035858.1 NP_057206.2 ENSEMBL proteins: ENSP00000447094 ENSP00000344655 ENSP00000380911 ENSP00000447783 ENSP00000448913 ENSP00000447449 ENSP00000380909 Human Recombinant Protein Products: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005575 cellular_component
ND --
CCDC41 for ontologies About GeneDecksing CCDC41 Antibody Products: Assay Products for CCDC41:
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Protein
Domains / Familiesfor CCDC41 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q9Y592
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Functionfor CCDC41 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC41 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC41 (see all 3 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): CCDC41 (NM_001042399 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC41 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CCDC41
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC41
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0003674 molecular_function
ND --
CCDC41 for ontologies About GeneDecksing
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Pathways & Interactionsfor CCDC41 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC41 1 Interacting protein for CCDC41 (Q9Y592 2 ) via UniProtKB, MINT, STRING, and/or I2D About this table Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0008150 biological_process
ND --
CCDC41 for ontologies About GeneDecksing
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Drugs & Compoundsfor CCDC41 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for CCDC41 Search CenterWatch for drugs/clinical trials and news about CCDC41 / CCD41
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Transcriptsfor CCDC41 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for CCDC41 gene (2 alternative transcripts): NM_001042399.1 NM_016122.2 Unigene Cluster for CCDC41:
Coiled-coil domain containing 41 Hs.279209 [show with all ESTs ] Unigene Representative Sequence: NM_016122 14 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000552632 ENST00000339839 (uc001tde.3 ) ENST00000397809 (uc001tdd.3 uc009zsw.1 )ENST00000546783 ENST00000547232 ENST00000546587 ENST00000547575 (uc001tdf.3 )ENST00000549352 ENST00000551250 ENST00000550328 ENST00000551078 ENST00000551596 ENST00000546527 ENST00000397807 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC41 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC41 (see all 3 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): CCDC41 (NM_001042399 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC41 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CCDC41
Additional cDNA sequence: AF155115.1 AK056316.1 BC011009.1 BC053614.1 BC063398.1 BC107746.1 BC125086.1 BC125087.1
9 DOTS entries : DT.95159018 DT.211508
DT.121195293 DT.95159016 DT.40129605 DT.100023136 DT.40130107 DT.92421898 DT.121195250 24/99 AceView cDNA sequences (see all 99 ):
AA770312 AA286755 AI927290 BC063398 BU176453 CA424794 AW438818 AA873647 CB160132 BX283278 BU616924 BE350623 F07672 AA732557 AW079265 BU608784 AA568651 BI821840 BC053614 AA865009 Z40717 AA515608 BI771416 BM083812 GeneLoc Exon Structure 5/10 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC41 (see all 10 ) About this scheme ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ SP1 :       -           -   -     -   -   -                   -     -     SP2 :     -   -           -   -     -   -   -                   -     -     SP3 :                       -   -   -                           SP4 :                                                     SP5 :                                                    
ExUns: 16a · 16b ^ 17a · 17b ^ 18 ^ 19 SP1 :   -   -         SP2 :             SP3 :             SP4 :             SP5 :            
ECgene alternative splicing isoforms for CCDC41
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Expression for CCDC41 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section CCDC41 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GTTGTCAGCA
About this image CCDC41 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See CCDC41 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CCDC41 SOURCE GeneReport for Unigene cluster: Hs.279209 SABiosciences Custom PCR Arrays for CCDC41 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for CCDC41Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat CCDC41 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat CCDC41 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat CCDC41 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC41
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Orthologsfor CCDC41 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for CCDC41 gene from 5/15 species (see all 15 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
mouse (Mus musculus)
Mammalia
Ccdc411 , 5
coiled-coil domain containing 411, 5
85.16(n) 1 84.1(a) 1
 
10 (49.05 cM) 5 77048 1 NM_029852.2 1 NP_084128.2 1 94688790 5
chicken (Gallus gallus)
Aves
CCDC411
coiled-coil domain containing 41
71.07(n) 67.67(a)
 
417904 XM_416146.3 XP_416146.2
lizard (Anolis carolinensis)
Reptilia
CCDC416
--
69(a)
1 ↔ 1
5(31177850-31205247)
African clawed frog (Xenopus laevis)
Amphibia
Xl.325982
Xenopus laevis transcribed sequence with weak similarity more
77.29(n)
 
BJ621028.1
zebrafish (Danio rerio)
Actinopterygii
LOC1000074721
coiled-coil domain-containing protein 41-like
59.26(n) 57.53(a)
 
100007472 XM_001345885.4 XP_001345921.4
ENSEMBL Gene Tree for CCDC41 (if available)TreeFam Gene Tree for CCDC41 (if available)
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Paralogsfor CCDC41 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for CCDC41 gene
CCDC41 for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for CCDC41 PGOHUM00000233641
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Genomic Variantsfor CCDC41 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 12 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for CCDC41 (94700225 - 94853764 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for CCDC41: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing CCDC41
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Disorders
/ Diseasesfor CCDC41 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
CCDC41 for disorders About GeneDecksing 3 diseases for CCDC41 : About MalaCards renal carcinoma carcinoma renal cell carcinoma Export disorders for CCDC41 gene to outside databases
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Publicationsfor CCDC41 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for CCDC41 gene integrated from 9 sources : (articles sorted by number of sources associating them with CCDC41) Utopia : connect your pdf to the dynamic world of online information
Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479) 1 , 2 , 3 Scanlan M.J....Old L.J. (1999) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) The finished DNA sequence of human chromosome 12. (PubMed id 16541075) 2 Scherer S.E.... Gibbs R.A. (2006) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548) 1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for CCDC41 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing CCDC41 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing CCDC41 gene
(According to HUGE )
About This Section --
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Specialized Databases showing CCDC41 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for CCDC41 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for CCDC41 gene: Search GeneIP for patents involving CCDC41 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor CCDC41 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for CCDC41 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for CCDC41 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for CCDC41 OriGene Protein Over-expression Lysate for CCDC41 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for CCDC41 OriGene 3'-UTR Clone for CCDC41 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC41 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC41 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for CCDC41 OriGene Custom Protein Services for CCDC41 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC41 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing CCDC41 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat CCDC41 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat CCDC41 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat CCDC41 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat CCDC41
Search Tocris compounds for CCDC41
CCDC41 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC41
Search ThermoFisher Antibodies for CCDC41
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CCDC41
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Aliases for CCDC41
Databases for CCDC41
Disorders / Diseases for CCDC41
Domains / Families for CCDC41
Drugs / Compounds for CCDC41
Expression for CCDC41
Function for CCDC41
Genomic Views for CCDC41
Intellectual Property for CCDC41
Orthologs for CCDC41
Paralogs for CCDC41
Pathways / Interactions for CCDC41
Products for CCDC41
Proteins for CCDC41
Publications for CCDC41
Search Box for CCDC41
Summaries for CCDC41
Transcripts for CCDC41
Variants for CCDC41
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