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Aliases for CCDC37 Gene

Aliases for CCDC37 Gene

  • Coiled-Coil Domain Containing 37 2 3
  • Coiled-Coil Domain-Containing Protein 37 3
  • MIA1 3

External Ids for CCDC37 Gene

Previous GeneCards Identifiers for CCDC37 Gene

  • GC03P127597
  • GC03P126113
  • GC03P123494

Summaries for CCDC37 Gene

GeneCards Summary for CCDC37 Gene

CCDC37 (Coiled-Coil Domain Containing 37) is a Protein Coding gene. Diseases associated with CCDC37 include facial paralysis. An important paralog of this gene is CCDC38.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC37 Gene

Genomics for CCDC37 Gene

Regulatory Elements for CCDC37 Gene

Genomic Location for CCDC37 Gene

126,394,908 bp from pter
126,436,556 bp from pter
41,649 bases
Plus strand

Genomic View for CCDC37 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC37 Gene

Proteins for CCDC37 Gene

  • Protein details for CCDC37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 37
    Protein Accession:
    Secondary Accessions:
    • D3DNA8
    • Q494V1
    • Q494V4
    • Q8N838

    Protein attributes for CCDC37 Gene

    611 amino acids
    Molecular mass:
    71117 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC37 Gene


neXtProt entry for CCDC37 Gene

Proteomics data for CCDC37 Gene at MOPED

Post-translational modifications for CCDC37 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC37 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for CCDC37 Gene

Domains for CCDC37 Gene

Protein Domains for CCDC37 Gene


Suggested Antigen Peptide Sequences for CCDC37 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC37: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC37 Gene

Function for CCDC37 Gene

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC37

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC37 Gene

Localization for CCDC37 Gene

Subcellular locations from

Jensen Localization Image for CCDC37 Gene COMPARTMENTS Subcellular localization image for CCDC37 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for CCDC37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region --
genes like me logo Genes that share ontologies with CCDC37: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC37 Gene

Pathways for CCDC37 Gene

SuperPathways for CCDC37 Gene

No Data Available

Interacting Proteins for CCDC37 Gene

Selected Interacting proteins: Q494V2-CCD37_HUMAN for CCDC37 Gene via MINT I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CCDC37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009405 pathogenesis --
genes like me logo Genes that share ontologies with CCDC37: view

No data available for Pathways by source for CCDC37 Gene

Transcripts for CCDC37 Gene

Unigene Clusters for CCDC37 Gene

Coiled-coil domain containing 37:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC37

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC37 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9
SP1: - - -

Relevant External Links for CCDC37 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC37 Gene

mRNA expression in normal human tissues for CCDC37 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC37 Gene

This gene is overexpressed in Testis (15.2), Fallopian Tube (9.1), Cervix - Endocervix (5.6), and Brain - Caudate (basal ganglia) (4.1).

SOURCE GeneReport for Unigene cluster for CCDC37 Gene Hs.591305

genes like me logo Genes that share expressions with CCDC37: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for CCDC37 Gene

Orthologs for CCDC37 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC37 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC37 35
  • 74.9 (n)
  • 67.73 (a)
CCDC37 36
  • 64 (a)
(Canis familiaris)
Mammalia CCDC37 35
  • 77.76 (n)
  • 71.38 (a)
CCDC37 36
  • 70 (a)
(Mus musculus)
Mammalia Ccdc37 35
  • 74.22 (n)
  • 66.9 (a)
Ccdc37 16
Ccdc37 36
  • 62 (a)
(Pan troglodytes)
Mammalia CCDC37 35
  • 99.24 (n)
  • 98.69 (a)
CCDC37 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc37 35
  • 75.22 (n)
  • 69.42 (a)
(Monodelphis domestica)
Mammalia CCDC37 36
  • 46 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC37 36
  • 29 (a)
(Gallus gallus)
Aves CCDC37 35
  • 55.31 (n)
  • 47.49 (a)
CCDC37 36
  • 45 (a)
(Anolis carolinensis)
Reptilia CCDC37 36
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc37 35
  • 54.8 (n)
  • 47.34 (a)
(Danio rerio)
Actinopterygii LOC100537661 35
  • 53.61 (n)
  • 43.1 (a)
ccdc37 36
  • 40 (a)
CCDC37 (2 of 2) 36
  • 39 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
Species with no ortholog for CCDC37:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC37 Gene

Gene Tree for CCDC37 (if available)
Gene Tree for CCDC37 (if available)

Paralogs for CCDC37 Gene

Paralogs for CCDC37 Gene

Selected SIMAP similar genes for CCDC37 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC37: view

Variants for CCDC37 Gene

Sequence variations from dbSNP and Humsavar for CCDC37 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs883052 -- 126,397,567(-) ACAGG(G/T)TCATA intron-variant
rs938388 -- 126,427,558(-) caaat(A/G)agttg intron-variant
rs951179 -- 126,431,105(+) AGATT(A/C)TCCAT intron-variant
rs1055451 -- 126,436,482(+) GGTCT(C/T)GAGTG utr-variant-3-prime
rs1065256 -- 126,411,987(-) TGTCA(A/C)ACCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC37 Gene

Variant ID Type Subtype PubMed ID
nsv877432 CNV Loss 21882294
dgv5245n71 CNV Loss 21882294
nsv877436 CNV Loss 21882294
nsv877438 CNV Loss 21882294
nsv829717 CNV Loss 17160897
nsv877439 CNV Loss 21882294

Relevant External Links for CCDC37 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC37 Gene

Disorders for CCDC37 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for CCDC37 Gene in MalaCards »

(1) Diseases for CCDC37 Gene including...

(2) University of Copenhagen DISEASES for CCDC37 Gene

Relevant External Links for CCDC37

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with CCDC37: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for CCDC37 Gene

Publications for CCDC37 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility. (PMID: 23569216) Yamamoto R. … Sale W.S. (J. Cell Biol. 2013) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Genome-wide analysis of DNA methylation and the gene expression change in lung cancer. (PMID: 22011669) Kwon Y.J. … Park J.H. (J Thorac Oncol 2012) 3

Products for CCDC37 Gene

Sources for CCDC37 Gene

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