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Aliases for CCDC36 Gene

Aliases for CCDC36 Gene

  • Coiled-Coil Domain Containing 36 2 3 5
  • Cancer/Testis Antigen 74 2 3 4
  • CT74 3 4

External Ids for CCDC36 Gene

Previous GeneCards Identifiers for CCDC36 Gene

  • GC03P049212
  • GC03P049084

Summaries for CCDC36 Gene

GeneCards Summary for CCDC36 Gene

CCDC36 (Coiled-Coil Domain Containing 36) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC36 Gene

Genomics for CCDC36 Gene

Regulatory Elements for CCDC36 Gene

Enhancers for CCDC36 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC36 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC36 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC36 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC36 Gene

49,198,428 bp from pter
49,258,157 bp from pter
59,730 bases
Plus strand

Genomic View for CCDC36 Gene

Genes around CCDC36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC36 Gene

Proteins for CCDC36 Gene

  • Protein details for CCDC36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 36
    Protein Accession:
    Secondary Accessions:
    • C9JJL0
    • Q05DG9
    • Q96LP7

    Protein attributes for CCDC36 Gene

    594 amino acids
    Molecular mass:
    66343 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH36202.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC36 Gene


neXtProt entry for CCDC36 Gene

Proteomics data for CCDC36 Gene at MOPED

Post-translational modifications for CCDC36 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC36 Gene

No data available for DME Specific Peptides for CCDC36 Gene

Domains & Families for CCDC36 Gene

Protein Domains for CCDC36 Gene


Suggested Antigen Peptide Sequences for CCDC36 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC36: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC36 Gene

Function for CCDC36 Gene

genes like me logo Genes that share phenotypes with CCDC36: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC36 Gene

Localization for CCDC36 Gene

Subcellular locations from

Jensen Localization Image for CCDC36 Gene COMPARTMENTS Subcellular localization image for CCDC36 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC36 Gene

Pathways & Interactions for CCDC36 Gene

SuperPathways for CCDC36 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0098792 xenophagy IMP 22020285
genes like me logo Genes that share ontologies with CCDC36: view

No data available for Pathways by source and SIGNOR curated interactions for CCDC36 Gene

Drugs & Compounds for CCDC36 Gene

No Compound Related Data Available

Transcripts for CCDC36 Gene

mRNA/cDNA for CCDC36 Gene

Unigene Clusters for CCDC36 Gene

Coiled-coil domain containing 36:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC36 Gene

No ASD Table

Relevant External Links for CCDC36 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC36 Gene

mRNA expression in normal human tissues for CCDC36 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC36 Gene

This gene is overexpressed in Testis (x23.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCDC36 Gene

SOURCE GeneReport for Unigene cluster for CCDC36 Gene Hs.631931

genes like me logo Genes that share expression patterns with CCDC36: view

Primer Products

No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC36 Gene

Orthologs for CCDC36 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC36 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC36 35
  • 78.93 (n)
  • 68.31 (a)
CCDC36 36
  • 69 (a)
(Canis familiaris)
Mammalia CCDC36 35
  • 83.39 (n)
  • 73.89 (a)
CCDC36 36
  • 73 (a)
(Mus musculus)
Mammalia Ccdc36 35
  • 74.11 (n)
  • 57.82 (a)
Ccdc36 16
Ccdc36 36
  • 57 (a)
(Pan troglodytes)
Mammalia CCDC36 35
  • 99.21 (n)
  • 98.65 (a)
CCDC36 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Ccdc36 35
  • 73.77 (n)
  • 59.33 (a)
(Monodelphis domestica)
Mammalia CCDC36 36
  • 41 (a)
(Gallus gallus)
Aves CCDC36 36
  • 47 (a)
(Anolis carolinensis)
Reptilia CCDC36 36
  • 53 (a)
(Danio rerio)
Actinopterygii CCDC36 36
  • 29 (a)
Species with no ortholog for CCDC36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC36 Gene

Gene Tree for CCDC36 (if available)
Gene Tree for CCDC36 (if available)

Paralogs for CCDC36 Gene

No data available for Paralogs for CCDC36 Gene

Variants for CCDC36 Gene

Sequence variations from dbSNP and Humsavar for CCDC36 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs13068038 - 49,256,817(+) AAAGA(A/C)AAGAA reference, missense
rs2334958 -- 49,214,931(-) tgggc(A/G)tggtg intron-variant
rs4384984 -- 49,252,445(-) GGAGA(A/C/T)CCTAT intron-variant
rs1436159 -- 49,237,802(-) CCTCA(A/G)AATCC intron-variant
rs10212301 -- 49,248,160(+) gctca(C/T)gcctg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC36 Gene

Variant ID Type Subtype PubMed ID
nsv876764 CNV Loss 21882294
nsv834686 CNV Loss 17160897
esv2675398 CNV Deletion 23128226

Variation tolerance for CCDC36 Gene

Residual Variation Intolerance Score: 39.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.07; 60.85% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CCDC36 Gene

Disorders for CCDC36 Gene

Relevant External Links for CCDC36

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC36 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC36 Gene

Publications for CCDC36 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 67
  2. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  3. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  4. Image-based genome-wide siRNA screen identifies selective autophagy factors. (PMID: 22020285) Orvedahl A. … Levine B. (Nature 2011) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CCDC36 Gene

Sources for CCDC36 Gene