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Aliases for CCDC36 Gene

Aliases for CCDC36 Gene

  • Coiled-Coil Domain Containing 36 2 3
  • Cancer/Testis Antigen 74 2 3 4
  • CT74 3 4
  • Coiled-Coil Domain-Containing Protein 36 3

External Ids for CCDC36 Gene

Summaries for CCDC36 Gene

GeneCards Summary for CCDC36 Gene

CCDC36 (Coiled-Coil Domain Containing 36) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC36 Gene

Genomics for CCDC36 Gene

Genomic Location for CCDC36 Gene

Start:
49,198,428 bp from pter
End:
49,258,201 bp from pter
Size:
59,774 bases
Orientation:
Plus strand

Genomic View for CCDC36 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC36 Gene

Regulatory Elements for CCDC36 Gene

Proteins for CCDC36 Gene

  • Protein details for CCDC36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IYA8-CCD36_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 36
    Protein Accession:
    Q8IYA8
    Secondary Accessions:
    • C9JJL0
    • Q05DG9
    • Q96LP7

    Protein attributes for CCDC36 Gene

    Size:
    594 amino acids
    Molecular mass:
    66343 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH36202.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC36 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC36 Gene

Proteomics data for CCDC36 Gene at MOPED

Post-translational modifications for CCDC36 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC36 Gene

No data available for DME Specific Peptides for CCDC36 Gene

Domains for CCDC36 Gene

Protein Domains for CCDC36 Gene

ProtoNet:
genes like me logo Genes that share domains with CCDC36: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC36 Gene

Function for CCDC36 Gene

Gene Ontology (GO) - Molecular Function for CCDC36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21516116
genes like me logo Genes that share ontologies with CCDC36: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC36 Gene

Localization for CCDC36 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC36 Gene COMPARTMENTS Subcellular localization image for CCDC36 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for CCDC36 Gene

Pathways for CCDC36 Gene

SuperPathways for CCDC36 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002230 positive regulation of defense response to virus by host IMP 22020285
genes like me logo Genes that share ontologies with CCDC36: view

No data available for Pathways by source for CCDC36 Gene

Transcripts for CCDC36 Gene

mRNA/cDNA for CCDC36 Gene

Unigene Clusters for CCDC36 Gene

Coiled-coil domain containing 36:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC36 Gene

No ASD Table

Relevant External Links for CCDC36 Gene

GeneLoc Exon Structure for
CCDC36
ECgene alternative splicing isoforms for
CCDC36

Expression for CCDC36 Gene

mRNA expression in normal human tissues for CCDC36 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC36 Gene

This gene is overexpressed in Testis (23.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC36 Gene

SOURCE GeneReport for Unigene cluster for CCDC36 Gene Hs.631931

genes like me logo Genes that share expressions with CCDC36: view

Orthologs for CCDC36 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC36 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC36 36
  • 99.21 (n)
  • 98.65 (a)
CCDC36 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC36 36
  • 78.93 (n)
  • 68.31 (a)
CCDC36 37
  • 69 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC36 36
  • 83.39 (n)
  • 73.89 (a)
CCDC36 37
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc36 36
  • 74.11 (n)
  • 57.82 (a)
Ccdc36 16
Ccdc36 37
  • 57 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC36 37
  • 41 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc36 36
  • 73.77 (n)
  • 59.33 (a)
chicken
(Gallus gallus)
Aves CCDC36 37
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC36 37
  • 53 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CCDC36 37
  • 29 (a)
OneToOne
Species with no ortholog for CCDC36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC36 Gene

ENSEMBL:
Gene Tree for CCDC36 (if available)
TreeFam:
Gene Tree for CCDC36 (if available)

Paralogs for CCDC36 Gene

No data available for Paralogs for CCDC36 Gene

Variants for CCDC36 Gene

Sequence variations from dbSNP and Humsavar for CCDC36 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1436159 -- 49,237,802(-) CCTCA(A/G)AATCC intron-variant
rs2082923 -- 49,217,739(-) caccc(A/G)caaat intron-variant
rs2099526 -- 49,232,325(-) tcaat(A/C)atgct intron-variant
rs2117938 -- 49,226,417(-) tcgcg(C/T)ggtta intron-variant
rs2334958 -- 49,214,931(-) tgggc(A/G)tggtg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC36 Gene

Variant ID Type Subtype PubMed ID
nsv876764 CNV Loss 21882294
nsv834686 CNV Loss 17160897
esv2675398 CNV Deletion 23128226

Relevant External Links for CCDC36 Gene

HapMap Linkage Disequilibrium report
CCDC36

Disorders for CCDC36 Gene

No disorders were found for CCDC36 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC36 Gene

Publications for CCDC36 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  3. Image-based genome-wide siRNA screen identifies selective autophagy factors. (PMID: 22020285) Orvedahl A. … Levine B. (Nature 2011) 3
  4. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for CCDC36 Gene

Sources for CCDC36 Gene

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