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Aliases for CCDC33 Gene

Aliases for CCDC33 Gene

  • Coiled-Coil Domain Containing 33 2 3 5
  • Cancer/Testis Antigen 61 2 3 4
  • CT61 3 4

External Ids for CCDC33 Gene

Previous GeneCards Identifiers for CCDC33 Gene

  • GC15P072347
  • GC15P072316
  • GC15P074509
  • GC15P051324

Summaries for CCDC33 Gene

GeneCards Summary for CCDC33 Gene

CCDC33 (Coiled-Coil Domain Containing 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC33 Gene

Genomics for CCDC33 Gene

Regulatory Elements for CCDC33 Gene

Enhancers for CCDC33 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC33 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC33 Gene

74,217,197 bp from pter
74,336,472 bp from pter
119,276 bases
Plus strand

Genomic View for CCDC33 Gene

Genes around CCDC33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC33 Gene

Proteins for CCDC33 Gene

  • Protein details for CCDC33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 33
    Protein Accession:
    Secondary Accessions:
    • A8K3U4
    • A8MPQ6
    • A8MV61
    • A8MVU9
    • B3KQ49
    • Q8TAX6
    • Q9H5Q6

    Protein attributes for CCDC33 Gene

    958 amino acids
    Molecular mass:
    107216 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC33 Gene


neXtProt entry for CCDC33 Gene

Proteomics data for CCDC33 Gene at MOPED

Post-translational modifications for CCDC33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC33 Gene

No data available for DME Specific Peptides for CCDC33 Gene

Domains & Families for CCDC33 Gene

Gene Families for CCDC33 Gene

Protein Domains for CCDC33 Gene


Suggested Antigen Peptide Sequences for CCDC33 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C2 domain.
  • Contains 1 C2 domain.
genes like me logo Genes that share domains with CCDC33: view

Function for CCDC33 Gene

genes like me logo Genes that share phenotypes with CCDC33: view

Animal Models for CCDC33 Gene

MGI Knock Outs for CCDC33:

Animal Model Products

miRNA for CCDC33 Gene

miRTarBase miRNAs that target CCDC33

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCDC33 Gene

Localization for CCDC33 Gene

Subcellular locations from

Jensen Localization Image for CCDC33 Gene COMPARTMENTS Subcellular localization image for CCDC33 gene
Compartment Confidence
cytosol 2
nucleus 2
golgi apparatus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC33 Gene

Pathways & Interactions for CCDC33 Gene

SuperPathways for CCDC33 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC33 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC33 Gene

Drugs & Compounds for CCDC33 Gene

No Compound Related Data Available

Transcripts for CCDC33 Gene

mRNA/cDNA for CCDC33 Gene

(11) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC33 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b ^ 19
SP1: - - - - -
SP3: -
SP4: -

Relevant External Links for CCDC33 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC33 Gene

mRNA expression in normal human tissues for CCDC33 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC33 Gene

This gene is overexpressed in Testis (x25.8), Fallopian Tube (x6.7), and Cervix - Endocervix (x4.2).

Protein differential expression in normal tissues from HIPED for CCDC33 Gene

This gene is overexpressed in Lymph node (18.1), Spleen (7.9), and Colon (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCDC33 Gene

SOURCE GeneReport for Unigene cluster for CCDC33 Gene Hs.383206

genes like me logo Genes that share expression patterns with CCDC33: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC33 Gene

Orthologs for CCDC33 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC33 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC33 35
  • 84.22 (n)
  • 77.55 (a)
CCDC33 36
  • 65 (a)
(Canis familiaris)
Mammalia CCDC33 35
  • 84.07 (n)
  • 77.91 (a)
CCDC33 36
  • 61 (a)
(Mus musculus)
Mammalia Ccdc33 35
  • 78.55 (n)
  • 72.96 (a)
Ccdc33 16
Ccdc33 36
  • 49 (a)
(Pan troglodytes)
Mammalia LOC100608474 35
  • 95.34 (n)
  • 93.52 (a)
CCDC33 36
  • 64 (a)
(Rattus norvegicus)
Mammalia Ccdc33 35
  • 78.96 (n)
  • 73.74 (a)
(Monodelphis domestica)
Mammalia CCDC33 36
  • 40 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC33 36
  • 45 (a)
(Gallus gallus)
Aves CCDC33 36
  • 23 (a)
(Danio rerio)
Actinopterygii ccdc33 36
  • 33 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 33 (a)
Species with no ortholog for CCDC33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC33 Gene

Gene Tree for CCDC33 (if available)
Gene Tree for CCDC33 (if available)

Paralogs for CCDC33 Gene

No data available for Paralogs for CCDC33 Gene

Variants for CCDC33 Gene

Sequence variations from dbSNP and Humsavar for CCDC33 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1564782 - 74,330,337(+) AGCCA(A/G)TGAGG reference, missense
rs2277603 - 74,330,192(+) AGGAG(A/G/T)TGAAC reference, missense
rs2277604 - 74,330,208(+) CCGGC(A/G/T)GGCCA reference, missense
VAR_045604 -
rs94899 -- 74,266,268(-) TTATG(C/T)CAGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC33 Gene

Variant ID Type Subtype PubMed ID
nsv833053 CNV Loss 17160897
nsv833054 CNV Loss 17160897
dgv2404n71 CNV Loss 21882294
nsv510938 CNV Complex 20534489
nsv471253 CNV Loss 18288195
dgv2405n71 CNV Loss 21882294
esv2666153 CNV Deletion 23128226
nsv1608 CNV Insertion 18451855
esv2674756 CNV Deletion 23128226
esv275019 CNV Loss 21479260
nsv1609 CNV Insertion 18451855

Variation tolerance for CCDC33 Gene

Residual Variation Intolerance Score: 81.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 13.38; 95.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC33 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC33 Gene

Disorders for CCDC33 Gene

Relevant External Links for CCDC33

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC33 Gene

Publications for CCDC33 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Phospho-tyrosine dependent protein-protein interaction network. (PMID: 25814554) Grossmann A. … Stelzl U. (Mol. Syst. Biol. 2015) 3
  4. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R. … Iakoucheva L.M. (Nat. Commun. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for CCDC33 Gene

Sources for CCDC33 Gene