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Aliases for CCDC30 Gene

Aliases for CCDC30 Gene

  • Coiled-Coil Domain Containing 30 2 3 5
  • Prefoldin Subunit 6-Like Protein 3 4
  • PFDN6L 3 4
  • Prefoldin 6-Like 2
  • PFD6L 3

External Ids for CCDC30 Gene

Previous GeneCards Identifiers for CCDC30 Gene

  • GC01P042778
  • GC01P042929
  • GC01P041120

Summaries for CCDC30 Gene

GeneCards Summary for CCDC30 Gene

CCDC30 (Coiled-Coil Domain Containing 30) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC30 Gene

Genomics for CCDC30 Gene

Regulatory Elements for CCDC30 Gene

Enhancers for CCDC30 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC30 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC30 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC30 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC30 Gene

42,463,318 bp from pter
42,654,664 bp from pter
191,347 bases
Plus strand

Genomic View for CCDC30 Gene

Genes around CCDC30 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC30 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC30 Gene

Proteins for CCDC30 Gene

  • Protein details for CCDC30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 30
    Protein Accession:
    Secondary Accessions:
    • Q14F06
    • Q5VVM5

    Protein attributes for CCDC30 Gene

    783 amino acids
    Molecular mass:
    91333 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC30 Gene


neXtProt entry for CCDC30 Gene

Proteomics data for CCDC30 Gene at MOPED

Post-translational modifications for CCDC30 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC30 Gene

No data available for DME Specific Peptides for CCDC30 Gene

Domains & Families for CCDC30 Gene

Protein Domains for CCDC30 Gene


Suggested Antigen Peptide Sequences for CCDC30 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the prefoldin subunit beta family.
  • Belongs to the prefoldin subunit beta family.
genes like me logo Genes that share domains with CCDC30: view

No data available for Gene Families for CCDC30 Gene

Function for CCDC30 Gene

Phenotypes for CCDC30 Gene

genes like me logo Genes that share phenotypes with CCDC30: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC30 Gene

Localization for CCDC30 Gene

Subcellular locations from

Jensen Localization Image for CCDC30 Gene COMPARTMENTS Subcellular localization image for CCDC30 gene
Compartment Confidence
extracellular 5
nucleus 3
cytosol 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC30 Gene

Pathways & Interactions for CCDC30 Gene

SuperPathways for CCDC30 Gene

No Data Available

Interacting Proteins for CCDC30 Gene

Gene Ontology (GO) - Biological Process for CCDC30 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC30 Gene

Drugs & Compounds for CCDC30 Gene

No Compound Related Data Available

Transcripts for CCDC30 Gene

mRNA/cDNA for CCDC30 Gene

(7) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(14) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC30 Gene

Coiled-coil domain containing 30:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC30 Gene

No ASD Table

Relevant External Links for CCDC30 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC30 Gene

mRNA expression in normal human tissues for CCDC30 Gene

Protein differential expression in normal tissues from HIPED for CCDC30 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (56.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC30 Gene

SOURCE GeneReport for Unigene cluster for CCDC30 Gene Hs.729640

mRNA Expression by UniProt/SwissProt for CCDC30 Gene

Tissue specificity: Expressed in brain, kidney, pancreas, placenta, liver, thymus and prostate.
genes like me logo Genes that share expression patterns with CCDC30: view

Protein tissue co-expression partners for CCDC30 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for CCDC30 Gene

Orthologs for CCDC30 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC30 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC30 35
  • 82.33 (n)
  • 69.28 (a)
CCDC30 36
  • 69 (a)
(Pan troglodytes)
Mammalia CCDC30 35
  • 99.49 (n)
  • 98.98 (a)
CCDC30 36
  • 99 (a)
(Canis familiaris)
Mammalia CCDC30 36
  • 69 (a)
(Monodelphis domestica)
Mammalia CCDC30 36
  • 52 (a)
(Mus musculus)
Mammalia Ccdc30 36
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC30 36
  • 28 (a)
(Gallus gallus)
Aves CCDC30 35
  • 56.42 (n)
  • 39.97 (a)
CCDC30 36
  • 30 (a)
(Danio rerio)
Actinopterygii CCDC30 36
  • 16 (a)
Species with no ortholog for CCDC30:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC30 Gene

Gene Tree for CCDC30 (if available)
Gene Tree for CCDC30 (if available)

Paralogs for CCDC30 Gene

(1) SIMAP similar genes for CCDC30 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with CCDC30: view

No data available for Paralogs for CCDC30 Gene

Variants for CCDC30 Gene

Sequence variations from dbSNP and Humsavar for CCDC30 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs16829829 - 42,653,990(+) AGACA(A/C)ATGGT reference, missense
rs988783 -- 42,652,510(-) TTTTT(A/C)AAATT intron-variant
rs1016544 -- 42,580,086(+) TTCCC(C/T)TTCTT intron-variant
rs1016545 -- 42,581,045(-) CTGGG(A/C)AACAT intron-variant
rs928651 -- 42,504,537(-) ATGGC(A/G)GATag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC30 Gene

Variant ID Type Subtype PubMed ID
nsv870704 CNV Gain 21882294
esv2480910 CNV Insertion 19546169
esv1025473 CNV Insertion 17803354
esv2747541 CNV Deletion 23290073
nsv829682 CNV Loss 17160897
nsv822453 CNV Loss 20364138
esv2520511 CNV Deletion 19546169

Variation tolerance for CCDC30 Gene

Residual Variation Intolerance Score: 51.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.67; 57.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC30 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC30 Gene

Disorders for CCDC30 Gene

Relevant External Links for CCDC30

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC30 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC30 Gene

Publications for CCDC30 Gene

  1. Cloning and characterization of a novel human prefoldin and SPEC domain protein gene (PFD6L) from the fetal brain. (PMID: 16710767) Zhang J. … Mao Y. (Biochem. Genet. 2006) 2 3 4 67
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3

Products for CCDC30 Gene

Sources for CCDC30 Gene