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CCDC28B Gene

protein-coding   GIFtS: 49
GCID: GC01P032666

Coiled-Coil Domain Containing 28B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Coiled-Coil Domain Containing 28B1 2
Coiled-Coil Domain-Containing Protein 28B2
MGC12035

External Ids:    HGNC: 281631   Entrez Gene: 791402   Ensembl: ENSG000001600507   OMIM: 6101625   UniProtKB: Q9BUN53   

Export aliases for CCDC28B gene to outside databases

Previous GC identifers: GC01P032336 GC01P032438 GC01P030782


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CCDC28B Gene:
The product of this gene localizes to centrosomes and basal bodies. It interacts and colocalizes with several
proteins associated with Bardet-Biedl syndrome (BBS). (provided by RefSeq, Jul 2008)

GeneCards Summary for CCDC28B Gene:
CCDC28B (coiled-coil domain containing 28B) is a protein-coding gene. Diseases associated with CCDC28B include bardet-biedl syndrome, modifier of, and congenital nystagmus. An important paralog of this gene is CCDC28A.

UniProtKB/Swiss-Prot: CC28B_HUMAN, Q9BUN5
Function: Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but
independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1
phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex

Gene Wiki entry for CCDC28B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC28B gene promoter:
         NF-1   HSF1 (long)   E47   Pax-3   POU2F1   POU2F1a   STAT3   Hand1   HSF1short   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC28B promoter sequence
   Search Chromatin IP Primers for CCDC28B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC28B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.11-p34.2   Ensembl cytogenetic band:  1p35.1   HGNC cytogenetic band: 1p36.11-p34.2

CCDC28B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC28B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P032666:  view genomic region     (about GC identifiers)

Start:
32,665,987 bp from pter      End:
32,670,991 bp from pter
Size:
5,005 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CC28B_HUMAN, Q9BUN5 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 28B  
Size: 200 amino acids; 22037 Da
Subunit: Interacts with BBS1, BBS2, BBS4, BBS5, BBS6, BBS7 and TTC8/BBS8. Interacts with MAPKAP1/SIN1 isoform 1
and RICTOR
Sequence caution: Sequence=CAI22057.1; Type=Erroneous gene model prediction;
Secondary accessions: A8K789 Q8TBV8
Alternative splicing: 2 isoforms:  Q9BUN5-1   Q9BUN5-3   

Explore the universe of human proteins at neXtProt for CCDC28B: NX_Q9BUN5

Explore proteomics data for CCDC28B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys112
  • Modification sites at PhosphoSitePlus

  • See CCDC28B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_077272.2  
    ENSEMBL proteins: 
     ENSP00000362704   ENSP00000435036   ENSP00000413017   ENSP00000431257  

    CCDC28B Human Recombinant Protein Products:

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    Novus Biologicals CCDC28B Protein
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    Cloud-Clone Corp. Proteins for CCDC28B

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    CCDC28B Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR025271 DUF4061

    Graphical View of Domain Structure for InterPro Entry Q9BUN5

    ProtoNet protein and cluster: Q9BUN5


    CCDC28B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CC28B_HUMAN, Q9BUN5
    Function: Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but
    independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1
    phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16327777
         
    CCDC28B for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC28B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC28B
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    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CCDC28B (see all 10):
    hsa-miR-224 hsa-miR-27a hsa-miR-29a hsa-miR-29c hsa-miR-128 hsa-miR-3681* hsa-miR-29b-1* hsa-miR-637
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CCDC28B

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: CCDC28B (NM_024296)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC28B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC28B

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC28B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CC28B_HUMAN, Q9BUN5: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=It localizes near
    centrosomes and basal bodies
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA16327777

    CCDC28B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC28B
    Interactions:

        Search GeneGlobe Interaction Network for CCDC28B

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042384cilium assembly IMP--

    CCDC28B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC28B (CC28B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CCDC28B gene: 
    NM_024296.3  

    Unigene Cluster for CCDC28B:

    Coiled-coil domain containing 28B
    Hs.534482  [show with all ESTs]
    Unigene Representative Sequence: AK126027
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373602(uc001bul.1) ENST00000469003 ENST00000421922(uc021okt.1)
    ENST00000461819 ENST00000483009
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CCDC28B (see all 10):
    hsa-miR-224 hsa-miR-27a hsa-miR-29a hsa-miR-29c hsa-miR-128 hsa-miR-3681* hsa-miR-29b-1* hsa-miR-637
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CCDC28B
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC28B
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC28B (NM_024296)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC28B
    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat CCDC28B
      QuantiFast Probe-based Assays in human, mouse, rat CCDC28B

    Additional mRNA sequence: 

    AK092702.1 AK126027.1 AK225113.1 AK291904.1 BC022848.2 

    5 DOTS entries:

    DT.215092  DT.100748653  DT.86840926  DT.91919747  DT.99935076 

    Selected AceView cDNA sequences (see all 332):

    BU506849 BQ478129 AI932678 BQ054155 BM471221 AA281337 BC065263 AI816239 
    AI146364 BU538767 AA376284 BE857092 BU735558 AA687434 BC046565 BU726101 
    BF939517 BQ063045 BQ057342 AI394288 AI382561 BC029686 AL121132 AA724204 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCDC28B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGGCTCAGC
    CCDC28B Expression
    About this image

    CCDC28B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC28B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.534482
        Custom PCR Arrays for CCDC28B
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    QuantiFast Probe-based Assays in human, mouse, rat CCDC28B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC28B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CCDC28B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc28b1 , 5 coiled coil domain containing 28B1, 5 88.83(n)1
    96.5(a)1
      4 (63.26 cM)5
    662641  NM_025455.21  NP_079731.21 
     1296192745 
    chicken
    (Gallus gallus)
    Aves CCDC28B1 coiled-coil domain containing 28B 71.91(n)
    69.1(a)
      419647  XM_004947824.1  XP_004947881.1 
    lizard
    (Anolis carolinensis)
    Reptilia CCDC28B6
    coiled-coil domain containing 28B
    70(a)
    1 ↔ 1
    GL343706.1(134179-143788)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.97392 Xenopus laevis transcribed sequence with weak similarity more 80.19(n)    CA973705.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ccdc28b1 coiled-coil domain containing 28B 62.96(n)
    64.44(a)
      559814  NM_001145573.1  NP_001139045.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG108746
    --
    18(a)
    1 → many
    2L(2189913-2192371)


    ENSEMBL Gene Tree for CCDC28B (if available)
    TreeFam Gene Tree for CCDC28B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CCDC28B gene
    CCDC28A2  
    1 SIMAP similar gene for CCDC28B using alignment to 3 protein entries:     CC28B_HUMAN (see all proteins):
    CCDC28A

    CCDC28B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCDC28B (see all 158)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1850596961,2
    --32743705(+) GGGGGC/TGAGGC 1 -- us2k10--------
    rs1909331321,2
    --32743727(+) TCTGGA/GTACCA 1 -- us2k10--------
    rs1387679331,2
    --32743790(+) TTCAAC/TAGGAA 1 -- us2k10--------
    rs1830825841,2
    --32743840(+) AGGCAC/TAGGCC 1 -- us2k10--------
    rs793870041,2
    C,F--32743886(+) CACTGC/GTATTT 1 -- us2k11Minor allele frequency- G:0.07EA 120
    rs1418888151,2
    --32743957(+) CTCTAA/GTTGTA 1 -- us2k10--------
    rs1874615091,2
    --32743997(+) TTCAGA/TTTTTA 1 -- us2k10--------
    rs1903761601,2
    --32744175(+) CCAGGA/CCTCCA 1 -- us2k10--------
    rs168349261,2
    C,F,H--32744202(+) CAATGA/GCTGTG 1 -- us2k125Minor allele frequency- G:0.18NA NS EA WA CSA 2467
    rs1444262781,2
    C--32744305(+) GGTGT-/GGGGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCDC28B (32665987 - 32670991 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CCDC28B: --
    Human Gene Mutation Database (HGMD): CCDC28B
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC28B
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC28B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610162   
    OMIM disorders: 209900  
    UniProtKB/Swiss-Prot: CC28B_HUMAN, Q9BUN5
  • Bardet-Biedl syndrome (BBS) [MIM:209900]: A syndrome characterized by usually severe pigmentary
    retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation.
    Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome
    inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus)
    may be required for clinical manifestation of some forms of the disease. Note=The gene represented in this entry
    acts as a disease modifier

  • 11 diseases for CCDC28B:    
    About MalaCards
    bardet-biedl syndrome, modifier of    congenital nystagmus    asphyxiating thoracic dystrophy    senior-loken syndrome
    bardet-biedl syndrome    retinal disease    joubert syndrome    retinal degeneration
    retinitis    multiple myeloma    myeloma

    2 diseases from the University of Copenhagen DISEASES database for CCDC28B:
    Bardet-Biedl syndrome     Congenital nystagmus

    CCDC28B for disorders           About GeneDecksing

    Genetic Association Database (GAD): CCDC28B
    Human Genome Epidemiology (HuGE) Navigator: CCDC28B (1 document)

    Export disorders for CCDC28B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCDC28B gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with CCDC28B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dissection of epistasis in oligogenic Bardet-Biedl syndrome. (PubMed id 16327777)1, 2, 3 Badano J.L.... Katsanis N. (Nature 2006)
    2. Characterization of CCDC28B reveals its role in ciliogenesis and provides insight to understand its modifier effect on Bardet-Biedl syndrome. (PubMed id 23015189)1, 2 Cardenas-Rodriguez M.... Badano J.L. (Hum. Genet. 2013)
    3. BBS7 and TTC8 (BBS8) mutations play a minor role in the mutational load of Bardet-Biedl syndrome in a multiethnic population. (PubMed id 19402160)1, 4 Bin J....HAcon E. (Hum. Mutat. 2009)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. The Bardet-Biedl syndrome-related protein CCDC28B modulates mTORC2 function and interacts with SIN1 to control cilia length independently of the mTOR complex. (PubMed id 23727834)2 Cardenas-Rodriguez M....Badano J.L. (Hum. Mol. Genet. 2013)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79140 HGNC: 28163 AceView: MGC1203andDKFZp451J0118 Ensembl:ENSG00000160050 euGenes: HUgn79140
    ECgene: CCDC28B H-InvDB: CCDC28B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CCDC28B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCDC28B gene:
    Search GeneIP for patents involving CCDC28B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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