|
|
coiled-coil domain containing 26
| |
Aliases
for CCDC26 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): lncRNA
Quality score for this RNA gene is 3
| Aliases |
|---|
| Coiled-Coil Domain Containing 261 2 | | RAM1 2 3 5 | | MGC274341 | | Retinoic Acid Modulator3 | | CCD265 |
| External Ids: | HGNC: 284161 | Entrez Gene: 1371962 | Ensembl: ENSG000002291407 | OMIM: 6130405 | UniProtKB: Q8TAB73 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n385464 n370216 | |
Export aliases for CCDC26 gene to outside databasesPrevious GC identifer: GC08U901094
Summaries
for CCDC26 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC26 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.9 NT_008046.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for CCDC26
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC26
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC26 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24.21 Ensembl cytogenetic band: 8q24.21 HGNC cytogenetic band: 8q24.21CCDC26 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M130434: view genomic region
(about GC identifiers)
Start:
|
130,363,937 bp from pter |
End:
|
130,692,485 bp from pter |
Size:
|
328,549 bases |
Orientation:
|
minus strand |
ORGUL member locations:
Legend (see complete legend)
130363937 130528211 130692485 chr8
|
Proteins
for CCDC26 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCD26_HUMAN, Q8TAB7 (See
protein sequence)Recommended Name: Putative coiled-coil domain-containing protein 26 Size: 109 amino acids; 13192 Da
Caution: Product of a dubious gene predictionExplore the universe of human proteins at neXtProt for CCDC26: NX_Q8TAB7
CCDC26 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_659487.1
Human Recombinant Protein Products:
CCDC26 Antibody Products:
Assay Products for CCDC26: |
Protein
Domains /
Families
for CCDC26 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8TAB7 |
Function
for CCDC26 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for CCDC26 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC26
|
Drugs & Compounds
for CCDC26 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC26
Search CenterWatch for drugs/clinical trials and news about CCDC26 
|
Transcripts
for CCDC26 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC26 gene: NM_145050.3 Unigene Cluster for CCDC26: Coiled-coil domain containing 26 Hs.679457 [show with all ESTs]Unigene Representative Sequence: BC0701523 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523151(lincRNA) ENST00000446592(lincRNA) ENST00000520048(lincRNA)
Additional cDNA sequence: BC026098.1 BC070152.1 3 DOTS entries: DT.97814375 DT.91924283 DT.95359906 23 AceView cDNA sequences: AA628201 BX101553 AI032482 BC070152 BC026098 BX097638 BG505008 NM_145050 BG494756 BG532915 AA009754 BU186641 CA391588 BG393664 AV730804 BG393734 BF184063 BG531028 T83203 BF976785 BG528201 BG527998 BF104016
GeneLoc Exon Structure
|
Expression
for CCDC26 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for CCDC26:none
CCDC26 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATATCAATAT
About this image
Genevestigator expression for CCDC26
SOURCE GeneReport for Unigene cluster: Hs.679457
UniProtKB/Swiss-Prot: CCD26_HUMAN, Q8TAB7Tissue specificity: Based on cell line studies, may be restricted to the myelocyte-monocyte lineage
SABiosciences Custom PCR Arrays for CCDC26
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC26
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CCDC26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC26 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC26 |
Orthologs
for CCDC26 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for CCDC26 (if available)
TreeFam Gene Tree for CCDC26 (if available) |
Paralogs
for CCDC26 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CCDC26 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CCDC26 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCDC26 for disorders About GeneDecksing
OMIM gene information: 613040
OMIM disorders: --
2  diseases for CCDC26: About MalaCardscleft lip cleft palate
1 disease from the University of Copenhagen DISEASES database for CCDC26:Malignant glioma Human Genome Epidemiology (HuGE) Navigator: CCDC26 (5 documents)
Export disorders for CCDC26 gene to outside databases
|
Publications
for CCDC26 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC26 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with CCDC26) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM. (PubMed id 16449964)1, 2, 3, 9 Yin W....Gronemeyer H. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Differential distribution of CCDC26 glioma-risk allele s in myeloid malignancies with mutant IDH1 compared with their IDH2R140-mutated or IDH-unmutated counterparts. (PubMed id 22116548)1 Lasho T.L....Jenkins R.B. (2012)
- Polymorphisms of TREH, IL4R and CCDC26 genes associate d with risk of glioma. (PubMed id 22369735)1 Li S....Zhang Y. (2012)
- Chromosome 7p11.2 (EGFR) variation influences glioma risk. (PubMed id 21531791)1 Sanson M....Simon M. (2011)
- Joint associations between genetic variants and repro ductive factors in glioma risk among women. (PubMed id 21920947)1 Wang S.S....Rajaraman P. (2011)
- Interaction between 5 genetic variants and allergy in glioma risk. (PubMed id 20462933)1 Schoemaker M.J....Swerdlow A.J. (2010)
- Genetic risk profiles identify different molecular et iologies for glioma. (PubMed id 20847058)1 Simon M....Sanson M. (2010)
- Genome-wide association study identifies five suscept ibility loci for glioma. (PubMed id 19578367)1 Shete S....Houlston R.S. (2009)
- Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. (PubMed id 19270707)1 Birnbaum S....Mangold E. (2009)
|
External Searches for CCDC26 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC26 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC26 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC26 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC26 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC26 gene:
Search GeneIP for patents involving CCDC26
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC26 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 |
| | | | |
 |
 |
|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC26 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC26 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC26 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC26 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC26 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCDC26 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CCDC26 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for CCDC26 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CCDC26 |
|
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|
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