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Aliases for CCDC23 Gene

Aliases for CCDC23 Gene

  • Coiled-Coil Domain Containing 23 2 3

External Ids for CCDC23 Gene

Previous GeneCards Identifiers for CCDC23 Gene

  • GC01M042942
  • GC01M043045
  • GC01M043272
  • GC01M041392

Summaries for CCDC23 Gene

GeneCards Summary for CCDC23 Gene

CCDC23 (Coiled-Coil Domain Containing 23) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC23 Gene

Genomics for CCDC23 Gene

Regulatory Elements for CCDC23 Gene

Transcription factor binding sites by QIAGEN in the CCDC23 gene promoter:

Genomic Location for CCDC23 Gene

Start:
42,807,052 bp from pter
End:
42,817,388 bp from pter
Size:
10,337 bases
Orientation:
Minus strand

Genomic View for CCDC23 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC23 Gene

Proteins for CCDC23 Gene

  • Protein details for CCDC23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N300-CCD23_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 23
    Protein Accession:
    Q8N300
    Secondary Accessions:
    • A8K5P1
    • D3DPW7

    Protein attributes for CCDC23 Gene

    Size:
    66 amino acids
    Molecular mass:
    7808 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC23 Gene

Proteomics data for CCDC23 Gene at MOPED

Post-translational modifications for CCDC23 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC23 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC23 Gene

Domains for CCDC23 Gene

Protein Domains for CCDC23 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC23 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N300

UniProtKB/Swiss-Prot:

CCD23_HUMAN :
  • Q8N300
Family:
  • Belongs to the CCDC23 family.
genes like me logo Genes that share domains with CCDC23: view

No data available for Gene Families for CCDC23 Gene

Function for CCDC23 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC23 Gene

Localization for CCDC23 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC23 Gene COMPARTMENTS Subcellular localization image for CCDC23 gene
Compartment Confidence
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for CCDC23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045177 apical part of cell IDA 20736312
genes like me logo Genes that share ontologies with CCDC23: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC23 Gene

Pathways for CCDC23 Gene

SuperPathways for CCDC23 Gene

No Data Available

Interacting Proteins for CCDC23 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000361599%0d%0a9606.ENSP00000167106%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000361599 Q8N300-CCD23_HUMAN for CCDC23 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for CCDC23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009306 protein secretion IDA 20736312
GO:0010596 negative regulation of endothelial cell migration IGI 20736312
GO:0031397 negative regulation of protein ubiquitination IDA 20736312
genes like me logo Genes that share ontologies with CCDC23: view

No data available for Pathways by source for CCDC23 Gene

Transcripts for CCDC23 Gene

mRNA/cDNA for CCDC23 Gene

(114) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC23 Gene

Coiled-coil domain containing 23:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC23 Gene

No ASD Table

Relevant External Links for CCDC23 Gene

GeneLoc Exon Structure for
CCDC23
ECgene alternative splicing isoforms for
CCDC23

Expression for CCDC23 Gene

mRNA expression in normal human tissues for CCDC23 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC23 Gene

SOURCE GeneReport for Unigene cluster for CCDC23 Gene Hs.113919

genes like me logo Genes that share expressions with CCDC23: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC23 Gene

Orthologs for CCDC23 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC23 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC23 35
  • 100 (n)
  • 100 (a)
CCDC23 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC23 35
  • 94.44 (n)
  • 95.45 (a)
CCDC23 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC23 35
  • 94.44 (n)
  • 95.45 (a)
CCDC23 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc23 35
  • 89.39 (n)
  • 93.94 (a)
Ccdc23 16
Ccdc23 36
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC23 36
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc23 35
  • 90.4 (n)
  • 93.94 (a)
lizard
(Anolis carolinensis)
Reptilia CCDC23 36
  • 70 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CCDC23 36
  • 68 (a)
OneToOne
Species with no ortholog for CCDC23:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC23 Gene

ENSEMBL:
Gene Tree for CCDC23 (if available)
TreeFam:
Gene Tree for CCDC23 (if available)

Paralogs for CCDC23 Gene

No data available for Paralogs for CCDC23 Gene

Variants for CCDC23 Gene

Sequence variations from dbSNP and Humsavar for CCDC23 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs7563 -- 42,807,169(+) ttttt(A/T)aaaaa utr-variant-3-prime
rs8322 -- 42,807,145(+) GTTTT(G/T)TGTGT utr-variant-3-prime
rs191229 -- 42,806,873(+) AAGGT(C/T)TGCAA downstream-variant-500B
rs225753 -- 42,806,985(+) CTTTT(C/T)TTACC downstream-variant-500B
rs225754 -- 42,807,017(+) ATTTT(C/T)TACGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for CCDC23 Gene

Variant ID Type Subtype PubMed ID
esv2668067 CNV Deletion 23128226

Relevant External Links for CCDC23 Gene

HapMap Linkage Disequilibrium report
CCDC23

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC23 Gene

Disorders for CCDC23 Gene

No disorders were found for CCDC23 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC23 Gene

Publications for CCDC23 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Isolation of a small vasohibin-binding protein (SVBP) and its role in vasohibin secretion. (PMID: 20736312) Suzuki Y. … Sato Y. (J. Cell. Sci. 2010) 3
  4. Vasohibin 2 is transcriptionally activated and promotes angiogenesis in hepatocellular carcinoma. (PMID: 22614011) Xue X. … Kondo Y. (Oncogene 2013) 3
  5. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3

Products for CCDC23 Gene

Sources for CCDC23 Gene

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