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CCDC22 Gene

protein-coding   GIFtS: 53
GCID: GC0XP049092

Coiled-Coil Domain Containing 22

(Previous name: chromosome X open reading frame 37)
(Previous symbol: CXorf37)
  See CCDC22-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Coiled-Coil Domain Containing 221 2
CXorf371 2 3
Chromosome X Open Reading Frame 371
Coiled-Coil Domain-Containing Protein 222

External Ids:    HGNC: 289091   Entrez Gene: 289522   Ensembl: ENSG000001019977   OMIM: 3008595   UniProtKB: O608263   

Export aliases for CCDC22 gene to outside databases

Previous GC identifers: GC0XP048849 GC0XP048978 GC0XP046750


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CCDC22 Gene:
This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of
NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper
metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which
are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been
identified as a novel candidate gene for syndromic X-linked intellectual disability. (provided by RefSeq, Aug
2013)

GeneCards Summary for CCDC22 Gene:
CCDC22 (coiled-coil domain containing 22) is a protein-coding gene. Diseases associated with CCDC22 include intellectual disability.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_079573.5  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC22 gene promoter:
         E2F-4   E2F-3a   E2F-5   Sp1   AP-1   Nkx2-5   E2F-2   E2F   E2F-1   HOXA5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC22 promoter sequence
   Search Chromatin IP Primers for CCDC22

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.23

CCDC22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC22 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP049092:  view genomic region     (about GC identifiers)

Start:
49,091,927 bp from pter      End:
49,106,987 bp from pter
Size:
15,061 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CCD22_HUMAN, O60826 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 22  
Size: 627 amino acids; 70756 Da
Subunit: Interacts with CPNE1 and CPNE4 (By similarity)
Secondary accessions: A8K7G1

Explore the universe of human proteins at neXtProt for CCDC22: NX_O60826

Explore proteomics data for CCDC22 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys162
  • Modification sites at PhosphoSitePlus

  • See CCDC22 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_054727.1  
    ENSEMBL proteins: 
     ENSP00000365401  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008530 DUF812

    Graphical View of Domain Structure for InterPro Entry O60826

    ProtoNet protein and cluster: O60826

    UniProtKB/Swiss-Prot: CCD22_HUMAN, O60826
    Similarity: Belongs to the CCDC22 family


    Find genes that share domains with CCDC22           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CCDC22           About GenesLikeMe


    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target CCDC22:
    hsa-mir-1 (MIRT023813), hsa-mir-92b-3p (MIRT040693), hsa-mir-93-3p (MIRT038882)

    Block miRNA regulation of human, mouse, rat CCDC22 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CCDC22:
    hsa-miR-548g hsa-miR-450b-3p
    SwitchGear 3'UTR luciferase reporter plasmidCCDC22 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CCDC22

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    GenScript: all cDNA clones in your preferred vector: CCDC22 (NM_014008)
    Sino Biological Human cDNA Clone for CCDC22
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC22

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC22


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    Find genes that share ontologies with CCDC22           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC22
    Interactions:

        Search GeneGlobe Interaction Network for CCDC22

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for CCDC22 (O608263 ENSP000003654014) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BLOC1S6Q9UL453, ENSP000002205314I2D: score=1 STRING: ENSP00000220531
    CPNE1Q998293, ENSP000003172574I2D: score=2 STRING: ENSP00000317257
    CCDC53Q9Y3C03I2D: score=5 
    EXOC1Q9NV703I2D: score=5 
    MTMR9Q96QG73I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with CCDC22           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC22 (CCD22)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CCDC22 gene: 
    NM_014008.4  

    Unigene Cluster for CCDC22:

    Coiled-coil domain containing 22
    Hs.26333  [show with all ESTs]
    Unigene Representative Sequence: NM_014008
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376227(uc011mna.2 uc004dnd.2) ENST00000496651 ENST00000490300

    miRNA
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    Block miRNA regulation of human, mouse, rat CCDC22 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CCDC22:
    hsa-miR-548g hsa-miR-450b-3p
    SwitchGear 3'UTR luciferase reporter plasmidCCDC22 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CCDC22
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC22
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    OriGene clones in human, mouse for CCDC22 (see all 7)
    OriGene ORF clones in mouse, rat for CCDC22
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC22 (NM_014008)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC22
    Primer
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    OriGene qPCR primer pairs and template standards for CCDC22
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC22
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC22
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC22
      QuantiFast Probe-based Assays in human, mouse, rat CCDC22

    Additional mRNA sequence: 

    AJ005890.1 AK291976.1 AK298264.1 AK316375.1 BC000972.2 BC011675.2 

    4 DOTS entries:

    DT.210533  DT.100736036  DT.95100152  DT.97785205 

    Selected AceView cDNA sequences (see all 125):

    CR610841 BQ057037 CK906295 BX283096 BM930782 BU857824 NM_014008 BU857192 
    BE503433 BM126841 CR611380 BM994660 AJ005890 BF062965 BQ188624 BG912845 
    BE045372 BC000972 BQ689457 BQ276363 BQ109453 BX333378 BC011675 AI439692 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CCDC22 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
    SP1:                          -                       -                                                                                             
    SP2:                          -                       -                                                                                             
    SP3:                                                                                                                                                
    SP4:                                                  -                                                                                             
    SP5:                          -           -           -                                                                                             


    ECgene alternative splicing isoforms for CCDC22

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCDC22 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGGGAGCTC
    CCDC22 Expression
    About this image

    CCDC22 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC22 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.26333

    UniProtKB/Swiss-Prot: CCD22_HUMAN, O60826
    Tissue specificity: Widely expressed in adult tissues and in fetal liver and brain, with highest levels in
    prostate and lowest in skeletal muscle

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CCDC22 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc221 , 5 coiled-coil domain containing 221, 5 85.7(n)1
    88.04(a)1
      X (3.42 cM)5
    546381  NM_138603.31  NP_613069.31 
     75938095 
    lizard
    (Anolis carolinensis)
    Reptilia CCDC226
    coiled-coil domain containing 22
    58(a)
    1 ↔ 1
    2(89071055-89108825)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC687572 hypothetical protein MGC68757 74.2(n)    BC060491.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.149172 Transcribed sequence with moderate similarity to protein more 75.4(n)    AL921474.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG99516
    --
    30(a)
    1 ↔ 1
    3L(16856264-16858089)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G558301 AT1G55830 44.89(n)
    34.68(a)
      842033  NM_001198315.1  NP_001185244.1 


    ENSEMBL Gene Tree for CCDC22 (if available)
    TreeFam Gene Tree for CCDC22 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCDC22 (see all 262)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs353621171,2
    C--46747415(-) AAAAA-/ATTGAC 1 -- us2k10--------
    rs1127567041,2
    C--46748352(+) CGCTCG/ACAGAA 1 -- ut511Minor allele frequency- A:0.00CSA 1
    rs2005883301,2
    C--46748568(+) CACCCA/CCGAAG 1 -- int10--------
    rs718965901,2
    C--46748710(+) ACACA-/CACACG
            
    CACAC
    1 -- int10--------
    rs59532791,2
    C,A--46748715(+) CACACG/ACACAC 1 -- int12Minor allele frequency- A:0.33NA CSA 3
    rs70593811,2
    C--46748725(+) cacacG/Acacgc 1 -- int11Minor allele frequency- A:0.00CSA 1
    rs1125682671,2
    C--46748727(+) CACACA/C/GCGCAC 1 -- int10--------
    rs1459613061,2
    C--46748781(+) ATCCTA/TTAACC 1 -- int10--------
    rs573886891,2
    C--46749068(+) TTTTT-/TCCTTT 1 -- int10--------
    rs576754331,2
    C,F--46749132(+) GTGGGA/GTGATC 1 -- int11Minor allele frequency- G:0.00WA 2

    HapMap Linkage Disequilibrium report for CCDC22 (49091927 - 49106987 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CCDC22:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6895CNV Insertion18451855
    nsv528292CNV Gain19592680
    nsv471602CNV Gain15918152
    esv32909CNV Gain+Loss17666407
    nsv469734CNV Complex16826518

    Human Gene Mutation Database (HGMD): CCDC22
    Locus Specific Mutation Databases (LSDB): CCDC22

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC22
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC22

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300859    OMIM disorders: --

    UniProtKB/Swiss-Prot: CCD22_HUMAN, O60826
  • Note=May be involved in X-linked syndromic mental retardation (PubMed:21826058). CCDC22 expression has
    been found to be down-regulated in a family with a phenotype consistent with X-linked syndromic mental
    retardation, and carrying variant Ala-17. In addition to intellectual disability, affected individuals have
    cardiac and skeletal abnormalities

  • 1 disease for CCDC22:    
    About MalaCards
    intellectual disability


    Find genes that share disorders with CCDC22           About GenesLikeMe

    Genetic Association Database (GAD): CCDC22
    Human Genome Epidemiology (HuGE) Navigator: CCDC22 (3 documents)

    Export disorders for CCDC22 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCDC22 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with CCDC22)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CCDC22: a novel candidate gene for syndromic X-linked intellectual disability. School of Medicine, University of California, Los Angeles, CA, USA. (PubMed id 21826058)1, 2 Voineagu I....Geschwind D. (Mol. Psychiatry 2012)
    2. Genetic variants harbored in the forkhead box protein 3 locus increase hay fever risk. (PubMed id 20398921)1, 4 Suttner K....Kabesch M. (J. Allergy Clin. Immunol. 2010)
    3. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)1, 4 Chapuis J....Lambert J.C. (Mol. Psychiatry 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. CCDC22 deficiency in humans blunts activation of proinflammatory NF-I_B signaling. (PubMed id 23563313)1 Starokadomskyy P....Burstein E. (J. Clin. Invest. 2013)
    7. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. Recruitment of the endosomal WASH complex is mediated by the extended 'tail' of Fam21 binding to the retromer protein Vps35. (PubMed id 22070227)1 Harbour M.E....Seaman M.N. (Biochem. J. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 28952 HGNC: 28909 AceView: CXorf37 Ensembl:ENSG00000101997 euGenes: HUgn28952
    ECgene: CCDC22 H-InvDB: CCDC22

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CCDC22 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCDC22 gene:
    Search GeneIP for patents involving CCDC22

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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