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Aliases for CCDC190 Gene

Aliases for CCDC190 Gene

  • Coiled-Coil Domain Containing 190 2 3 5
  • C1orf110 3 4
  • Coiled-Coil Domain-Containing Protein 190 3
  • Chromosome 1 Open Reading Frame 110 2

External Ids for CCDC190 Gene

Previous HGNC Symbols for CCDC190 Gene

  • C1orf110

Summaries for CCDC190 Gene

GeneCards Summary for CCDC190 Gene

CCDC190 (Coiled-Coil Domain Containing 190) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC190 Gene

Genomics for CCDC190 Gene

Regulatory Elements for CCDC190 Gene

Enhancers for CCDC190 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G162854 1.4 FANTOM5 ENCODE dbSUPER 15.2 +12.4 12417 4.3 ELF3 ATF1 KLF17 FEZF1 RAD21 GATA2 SCRT2 ZNF143 FOS ZNF654 CCDC190 RGS4 ENSG00000230739
GH01G162860 0.5 dbSUPER 23.8 +7.2 7209 2.0 CTCF IRF1 ZNF644 CCDC190 LOC101928404 ENSG00000230739
GH01G162904 1.4 Ensembl ENCODE dbSUPER 7.4 -36.6 -36597 2.4 ELF3 FOXA2 INSM2 KLF17 FEZF1 ZNF2 YY1 RARA TCF12 GATA4 CCDC190 ENSG00000227667
GH01G162877 0.7 dbSUPER 12.8 -9.4 -9382 1.7 CTCF ZNF654 TRIM22 REST ZNF2 RAD21 GATA3 JUND SMC3 ZNF143 CCDC190 ENSG00000227667
GH01G162872 1.3 Ensembl ENCODE dbSUPER 5.2 -5.1 -5124 2.2 ELF3 FOXA2 RARA YY1 GATA2 FOS MIXL1 HMG20B REST CEBPA LOC101928404 RGS4 CCDC190 ENSG00000227667
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC190 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC190 Gene

Chromosome:
1
Start:
162,824,458 bp from pter
End:
162,868,900 bp from pter
Size:
44,443 bases
Orientation:
Minus strand

Genomic View for CCDC190 Gene

Genes around CCDC190 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC190 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC190 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC190 Gene

Proteins for CCDC190 Gene

  • Protein details for CCDC190 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86UF4-CC190_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 190
    Protein Accession:
    Q86UF4
    Secondary Accessions:
    • Q5JSG1
    • Q6ZW57

    Protein attributes for CCDC190 Gene

    Size:
    302 amino acids
    Molecular mass:
    34103 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BC040018; Type=Frameshift; Positions=200; Evidence={ECO:0000305}; Sequence=CAI13459.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC190 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC190 Gene

Post-translational modifications for CCDC190 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC190 Gene

No data available for DME Specific Peptides for CCDC190 Gene

Domains & Families for CCDC190 Gene

Protein Domains for CCDC190 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC190 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC190: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC190 Gene

Function for CCDC190 Gene

genes like me logo Genes that share phenotypes with CCDC190: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC190 Gene

Localization for CCDC190 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC190 gene
Compartment Confidence
nucleus 3
mitochondrion 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC190 Gene

Pathways & Interactions for CCDC190 Gene

SuperPathways for CCDC190 Gene

No Data Available

Interacting Proteins for CCDC190 Gene

Selected Interacting proteins: Q86UF4-CC190_HUMAN for CCDC190 Gene via IID

Symbol External ID(s) Details
APP

Gene Ontology (GO) - Biological Process for CCDC190 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC190 Gene

Drugs & Compounds for CCDC190 Gene

No Compound Related Data Available

Transcripts for CCDC190 Gene

mRNA/cDNA for CCDC190 Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC190 Gene

No ASD Table

Relevant External Links for CCDC190 Gene

GeneLoc Exon Structure for
CCDC190
ECgene alternative splicing isoforms for
CCDC190

Expression for CCDC190 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC190 Gene:

CCDC190
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC190 Gene

Orthologs for CCDC190 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC190 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf110 34
  • 99.12 (n)
C1orf110 35
  • 83 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C3H1orf110 34
  • 78 (n)
C1orf110 35
  • 65 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C38H1orf110 34
  • 75.97 (n)
C1orf110 35
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700084C01Rik 34 35
  • 71.91 (n)
Ccdc190 16
rat
(Rattus norvegicus)
Mammalia RGD1560672 34
  • 71.58 (n)
oppossum
(Monodelphis domestica)
Mammalia C1orf110 35
  • 34 (a)
OneToOne
Species where no ortholog for CCDC190 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC190 Gene

ENSEMBL:
Gene Tree for CCDC190 (if available)
TreeFam:
Gene Tree for CCDC190 (if available)

Paralogs for CCDC190 Gene

No data available for Paralogs for CCDC190 Gene

Variants for CCDC190 Gene

Sequence variations from dbSNP and Humsavar for CCDC190 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000203446 -- 162,859,683(+) ACAAA(C/T)AACCT intron-variant
rs1000412395 -- 162,865,484(+) CACAG(A/G)TGGGC intron-variant, upstream-variant-2KB
rs1000575137 -- 162,861,646(+) TTCGG(G/T)GCTTA intron-variant, utr-variant-5-prime
rs1000893657 -- 162,870,497(+) AAAAC(A/C)ATTCT upstream-variant-2KB
rs1001198558 -- 162,851,928(+) TGAGA(A/G)GAGAG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for CCDC190 Gene

Variant ID Type Subtype PubMed ID
dgv215n106 CNV insertion 24896259
esv2666263 CNV deletion 23128226
nsv1125477 CNV tandem duplication 24896259
nsv1152937 CNV insertion 26484159
nsv516482 CNV gain+loss 19592680
nsv548081 CNV loss 21841781

Variation tolerance for CCDC190 Gene

Residual Variation Intolerance Score: 80.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.40; 42.44% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC190 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC190

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC190 Gene

Disorders for CCDC190 Gene

Relevant External Links for CCDC190

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC190
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC190

No disorders were found for CCDC190 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC190 Gene

Publications for CCDC190 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  5. Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. (PMID: 23266556) Peters U. … Hsu L. (Gastroenterology 2013) 3 64

Products for CCDC190 Gene

Sources for CCDC190 Gene

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