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Aliases for CCDC189 Gene

Aliases for CCDC189 Gene

  • Coiled-Coil Domain Containing 189 2 3 5
  • C16orf93 3 4
  • Chromosome 16 Open Reading Frame 93 2

External Ids for CCDC189 Gene

Previous HGNC Symbols for CCDC189 Gene

  • C16orf93

Summaries for CCDC189 Gene

GeneCards Summary for CCDC189 Gene

CCDC189 (Coiled-Coil Domain Containing 189) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC189 Gene

Genomics for CCDC189 Gene

Regulatory Elements for CCDC189 Gene

Enhancers for CCDC189 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC189 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC189 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC189 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC189 Gene

30,757,423 bp from pter
30,762,710 bp from pter
5,288 bases
Minus strand

Genomic View for CCDC189 Gene

Genes around CCDC189 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC189 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC189 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC189 Gene

Proteins for CCDC189 Gene

  • Protein details for CCDC189 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 189
    Protein Accession:
    Secondary Accessions:
    • A1A4V8
    • F5GX13
    • Q569G2

    Protein attributes for CCDC189 Gene

    331 amino acids
    Molecular mass:
    37921 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC189 Gene


neXtProt entry for CCDC189 Gene

Proteomics data for CCDC189 Gene at MOPED

Post-translational modifications for CCDC189 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC189 Gene

No data available for DME Specific Peptides for CCDC189 Gene

Domains & Families for CCDC189 Gene

Protein Domains for CCDC189 Gene


Suggested Antigen Peptide Sequences for CCDC189 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC189: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC189 Gene

Function for CCDC189 Gene

genes like me logo Genes that share phenotypes with CCDC189: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC189 Gene

Localization for CCDC189 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCDC189 Gene

Pathways & Interactions for CCDC189 Gene

SuperPathways for CCDC189 Gene

No Data Available

Interacting Proteins for CCDC189 Gene

Gene Ontology (GO) - Biological Process for CCDC189 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC189 Gene

Drugs & Compounds for CCDC189 Gene

No Compound Related Data Available

Transcripts for CCDC189 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC189 Gene

No ASD Table

Relevant External Links for CCDC189 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC189 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expression patterns with CCDC189: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC189 Gene

Orthologs for CCDC189 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC189 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C25H16orf93 35
  • 82.28 (n)
  • 77.04 (a)
C16orf93 36
  • 77 (a)
(Canis familiaris)
Mammalia C6H16orf93 35
  • 81.97 (n)
  • 77.2 (a)
C6H16orf93 36
  • 76 (a)
(Mus musculus)
Mammalia Gm166 35
  • 77.1 (n)
  • 72.34 (a)
Ccdc189 16
Gm166 36
  • 71 (a)
(Pan troglodytes)
Mammalia C16H16orf93 35
  • 98.99 (n)
  • 98.79 (a)
C16H16orf93 36
  • 91 (a)
(Rattus norvegicus)
Mammalia LOC691909 35
  • 77.24 (n)
  • 72.26 (a)
(Monodelphis domestica)
Mammalia C16orf93 36
  • 56 (a)
(Gallus gallus)
Aves C16orf93 36
  • 35 (a)
(Anolis carolinensis)
Reptilia C16orf93 36
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100493957 35
  • 51.6 (n)
  • 38.4 (a)
(Danio rerio)
Actinopterygii LOC100151516 35
  • 48.58 (n)
  • 35.47 (a)
C12H16orf93 36
  • 31 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
Species with no ortholog for CCDC189:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC189 Gene

Gene Tree for CCDC189 (if available)
Gene Tree for CCDC189 (if available)

Paralogs for CCDC189 Gene

No data available for Paralogs for CCDC189 Gene

Variants for CCDC189 Gene

Variation tolerance for CCDC189 Gene

Residual Variation Intolerance Score: 60.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.02; 68.49% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CCDC189 Gene

Disorders for CCDC189 Gene

Relevant External Links for CCDC189

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC189 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC189 Gene

Publications for CCDC189 Gene

  1. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CCDC189 Gene

Sources for CCDC189 Gene