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Aliases for CCDC188 Gene

Aliases for CCDC188 Gene

  • Coiled-Coil Domain Containing 188 2 3 5

External Ids for CCDC188 Gene

Summaries for CCDC188 Gene

GeneCards Summary for CCDC188 Gene

CCDC188 (Coiled-Coil Domain Containing 188) is a Protein Coding gene.

Additional gene information for CCDC188 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC188 Gene

Genomics for CCDC188 Gene

Regulatory Elements for CCDC188 Gene

Enhancers for CCDC188 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22H019958 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.3 +189.8 189785 6 HNRNPUL1 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B DMAP1 ZNF2 YY1 LINC01311 LOC100420177 UFD1 RPL7AP70 KLHL22 ENSG00000273343 ZNF74 MED15 DGCR8 COMT
GH22H020494 1.8 FANTOM5 ENCODE dbSUPER 11.3 -344.6 -344585 2 FEZF1 YBX1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 SP3 ZC3H11A MEF2D LZTR1 DGCR8 MED15 RPL7AP70 TRMT2A LOC100420177 RPL8P5 THAP7-AS1 THAP7 ENSG00000273343
GH22H020153 1.4 FANTOM5 Ensembl ENCODE 14.4 -3.5 -3541 2 CTCF MXI1 RB1 SAP130 ETV1 ARID4B MAX DMAP1 RAD21 ZNF121 CCDC188 ZDHHC8 GC22P020198
GH22H020114 1.4 ENCODE dbSUPER 9.7 +34.0 34014 4 HDGF PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 SLC30A9 LZTR1 TRMT2A MED15 TUBA3GP DGCR8 SCARF2 RPL7AP70 RANBP1 ESS2 LINC01311
GH22H020128 1.3 Ensembl ENCODE 8 +22.1 22129 1 HNRNPUL1 HDGF ATF1 FOXA2 ARNT ZNF2 YY1 GLIS2 ZNF143 ATF7 MED15 DGCR8 LOC100420177 TRMT2A LZTR1 RPL7AP70 LINC01311 ZDHHC8 UFD1 RPL8P5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC188 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC188 Gene

Chromosome:
22
Start:
20,148,417 bp from pter
End:
20,151,259 bp from pter
Size:
2,843 bases
Orientation:
Minus strand

Genomic View for CCDC188 Gene

Genes around CCDC188 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC188 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC188 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC188 Gene

Proteins for CCDC188 Gene

  • Protein details for CCDC188 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H7C350-CC188_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 188
    Protein Accession:
    H7C350

    Protein attributes for CCDC188 Gene

    Size:
    402 amino acids
    Molecular mass:
    43548 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC188 Gene

Post-translational modifications for CCDC188 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC188 Gene

No data available for DME Specific Peptides for CCDC188 Gene

Domains & Families for CCDC188 Gene

Gene Families for CCDC188 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for CCDC188 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC188: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC188 Gene

Function for CCDC188 Gene

Phenotypes From GWAS Catalog for CCDC188 Gene

genes like me logo Genes that share phenotypes with CCDC188: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC188 Gene

Localization for CCDC188 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC188 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CCDC188 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CCDC188: view

No data available for Subcellular locations from COMPARTMENTS for CCDC188 Gene

Pathways & Interactions for CCDC188 Gene

SuperPathways for CCDC188 Gene

No Data Available

Interacting Proteins for CCDC188 Gene

Gene Ontology (GO) - Biological Process for CCDC188 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC188 Gene

Drugs & Compounds for CCDC188 Gene

No Compound Related Data Available

Transcripts for CCDC188 Gene

mRNA/cDNA for CCDC188 Gene

(7) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC188 Gene

No ASD Table

Relevant External Links for CCDC188 Gene

GeneLoc Exon Structure for
CCDC188
ECgene alternative splicing isoforms for
CCDC188

Expression for CCDC188 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC188 Gene:

CCDC188
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC188 Gene

Orthologs for CCDC188 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC188 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC747175 33
  • 99.31 (n)
-- 34
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC100848428 33
  • 86.57 (n)
-- 34
  • 66 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1563782 33
  • 85.68 (n)
dog
(Canis familiaris)
Mammalia LOC100687283 33
  • 84.49 (n)
-- 34
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia LOC102638083 33
  • 84.04 (n)
Gm7873 34
  • 66 (a)
OneToOne
Ccdc188 16
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 38 (a)
OneToOne
Species where no ortholog for CCDC188 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC188 Gene

ENSEMBL:
Gene Tree for CCDC188 (if available)
TreeFam:
Gene Tree for CCDC188 (if available)

Paralogs for CCDC188 Gene

Pseudogenes.org Pseudogenes for CCDC188 Gene

genes like me logo Genes that share paralogs with CCDC188: view

No data available for Paralogs for CCDC188 Gene

Variants for CCDC188 Gene

Sequence variations from dbSNP and Humsavar for CCDC188 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000621538 -- 20,150,048(+) CCAGC(C/T)GGGTC intron-variant, upstream-variant-2KB, reference, synonymous-codon
rs1001229463 -- 20,151,356(+) ATGCC(C/T)GGCTA upstream-variant-2KB, utr-variant-5-prime
rs1002373228 -- 20,147,823(+) GGTAC(A/G)GCCTG downstream-variant-500B, utr-variant-3-prime
rs1003223890 -- 20,153,674(+) CTCTT(C/T)TTGTT upstream-variant-2KB
rs1003273565 -- 20,148,522(+) CACAG(G/T)GGTGC downstream-variant-500B, reference, synonymous-codon, missense, utr-variant-3-prime

Relevant External Links for CCDC188 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC188

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for CCDC188 Gene

Disorders for CCDC188 Gene

Relevant External Links for CCDC188

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC188

No disorders were found for CCDC188 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC188 Gene

Publications for CCDC188 Gene

  1. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 4 60

Products for CCDC188 Gene

Sources for CCDC188 Gene

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