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Aliases for CCDC185 Gene

Aliases for CCDC185 Gene

  • Coiled-Coil Domain Containing 185 2 3 5
  • C1orf65 3 4
  • Chromosome 1 Open Reading Frame 65 2

External Ids for CCDC185 Gene

Previous HGNC Symbols for CCDC185 Gene

  • C1orf65

Summaries for CCDC185 Gene

GeneCards Summary for CCDC185 Gene

CCDC185 (Coiled-Coil Domain Containing 185) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC185 Gene

Genomics for CCDC185 Gene

Regulatory Elements for CCDC185 Gene

Enhancers for CCDC185 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC185 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC185 Gene

Chromosome:
1
Start:
223,393,373 bp from pter
End:
223,395,470 bp from pter
Size:
2,098 bases
Orientation:
Plus strand

Genomic View for CCDC185 Gene

Genes around CCDC185 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC185 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC185 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC185 Gene

Proteins for CCDC185 Gene

  • Protein details for CCDC185 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N715-CC185_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 185
    Protein Accession:
    Q8N715
    Secondary Accessions:
    • Q8N746
    • Q8NA93

    Protein attributes for CCDC185 Gene

    Size:
    623 amino acids
    Molecular mass:
    72349 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC185 Gene

Proteomics data for CCDC185 Gene at MOPED

Post-translational modifications for CCDC185 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC185 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC185 Gene

Domains & Families for CCDC185 Gene

Protein Domains for CCDC185 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC185: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC185 Gene

Function for CCDC185 Gene

Phenotypes for CCDC185 Gene

genes like me logo Genes that share phenotypes with CCDC185: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC185 Gene

Localization for CCDC185 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCDC185 Gene

Pathways & Interactions for CCDC185 Gene

SuperPathways for CCDC185 Gene

No Data Available

Interacting Proteins for CCDC185 Gene

Gene Ontology (GO) - Biological Process for CCDC185 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC185 Gene

Drugs & Compounds for CCDC185 Gene

No Compound Related Data Available

Transcripts for CCDC185 Gene

mRNA/cDNA for CCDC185 Gene

(1) REFSEQ mRNAs :
(11) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC185 Gene

No ASD Table

Relevant External Links for CCDC185 Gene

GeneLoc Exon Structure for
CCDC185
ECgene alternative splicing isoforms for
CCDC185

Expression for CCDC185 Gene

mRNA expression in normal human tissues for CCDC185 Gene

Protein differential expression in normal tissues from HIPED for CCDC185 Gene

This gene is overexpressed in Frontal cortex (29.7), Fetal gut (15.9), and Tlymphocyte (11.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC185 Gene



genes like me logo Genes that share expression patterns with CCDC185: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC185 Gene

Orthologs for CCDC185 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC185 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C16H1orf65 35
  • 74.78 (n)
  • 61.2 (a)
C16H1orf65 36
  • 60 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4922505E12Rik 35
  • 71.36 (n)
  • 56.79 (a)
Ccdc185 16
4922505E12Rik 36
  • 54 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C1H1orf65 35
  • 98.98 (n)
  • 98.23 (a)
C1orf65 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC289334 35
  • 71.57 (n)
  • 56.36 (a)
dog
(Canis familiaris)
Mammalia C1orf65 36
  • 48 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C1orf65 36
  • 49 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C1orf65 36
  • 40 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C1orf65 36
  • 36 (a)
OneToOne
Species with no ortholog for CCDC185:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC185 Gene

ENSEMBL:
Gene Tree for CCDC185 (if available)
TreeFam:
Gene Tree for CCDC185 (if available)

Paralogs for CCDC185 Gene

No data available for Paralogs for CCDC185 Gene

Variants for CCDC185 Gene

Sequence variations from dbSNP and Humsavar for CCDC185 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_027066 -
VAR_027067 -
VAR_027068 -
VAR_027069 -
rs36041842 -- 223,395,795(+) GGTTT(-/T)GTTGT downstream-variant-500B

Variation tolerance for CCDC185 Gene

Residual Variation Intolerance Score: 42% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.64; 72.70% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CCDC185 Gene

Disorders for CCDC185 Gene

Relevant External Links for CCDC185

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC185

No disorders were found for CCDC185 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC185 Gene

Publications for CCDC185 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for CCDC185 Gene

Sources for CCDC185 Gene

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