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Aliases for CCDC182 Gene

Aliases for CCDC182 Gene

  • Coiled-Coil Domain Containing 182 2 3 5

External Ids for CCDC182 Gene

Previous GeneCards Identifiers for CCDC182 Gene

  • GC17M055822

Summaries for CCDC182 Gene

GeneCards Summary for CCDC182 Gene

CCDC182 (Coiled-Coil Domain Containing 182) is a Protein Coding gene.

Additional gene information for CCDC182 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC182 Gene

Genomics for CCDC182 Gene

Regulatory Elements for CCDC182 Gene

Enhancers for CCDC182 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H057602 1.8 FANTOM5 Ensembl ENCODE dbSUPER 21.2 +139.0 138976 7 FOXA2 ATF1 MLX ARID4B FEZF1 DMAP1 ZNF143 FOS ATF7 RUNX3 CCDC182 LOC101927557 ENSG00000264914 OR4D1 LOC100419768 SETP3 MSI2 LOC101927539 ENSG00000280028
GH17H058005 2.4 ENCODE dbSUPER 10 -261.2 -261176 4 MLX ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC SRSF1 MKS1 TEX14 ENSG00000264914 OR4D1 SETP3 LOC101927557 VEZF1 RAD51C CCDC182
GH17H058658 2.1 FANTOM5 Ensembl ENCODE dbSUPER 9.9 -913.7 -913682 2 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A SRSF1 MKS1 TRIM37 SMG8 RAD51C DHX40 SETP3 OR4D1 SPDYE22P ENSG00000264914
GH17H057983 1.8 FANTOM5 ENCODE dbSUPER 10 -242.3 -242284 7 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 MKS1 TEX14 SRSF1 ENSG00000264914 OR4D1 LOC101927557 SETP3 CCDC182 LOC101927666 VEZF1
GH17H057622 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +121.9 121858 2 BATF FOSL1 POLR2A EED FOSL2 FOS RCOR1 RUNX3 IKZF2 CREM CCDC182 GC17P057625 RN7SL449P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC182 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC182 Gene

Chromosome:
17
Start:
57,744,481 bp from pter
End:
57,745,329 bp from pter
Size:
849 bases
Orientation:
Minus strand

Genomic View for CCDC182 Gene

Genes around CCDC182 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC182 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC182 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC182 Gene

Proteins for CCDC182 Gene

  • Protein details for CCDC182 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NF36-CC182_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 182
    Protein Accession:
    A6NF36

    Protein attributes for CCDC182 Gene

    Size:
    153 amino acids
    Molecular mass:
    17536 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC182 Gene

Post-translational modifications for CCDC182 Gene

No Post-translational modifications

Other Protein References for CCDC182 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC182 Gene

Domains & Families for CCDC182 Gene

Gene Families for CCDC182 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC182 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC182: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC182 Gene

Function for CCDC182 Gene

Phenotypes From GWAS Catalog for CCDC182 Gene

Gene Ontology (GO) - Molecular Function for CCDC182 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with CCDC182: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC182 Gene

Localization for CCDC182 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC182 gene
Compartment Confidence
cytosol 3
nucleus 2
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for CCDC182 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with CCDC182: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for CCDC182 Gene

Pathways & Interactions for CCDC182 Gene

SuperPathways for CCDC182 Gene

No Data Available

Interacting Proteins for CCDC182 Gene

Gene Ontology (GO) - Biological Process for CCDC182 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008585 female gonad development IEA,ISS --
genes like me logo Genes that share ontologies with CCDC182: view

No data available for Pathways by source and SIGNOR curated interactions for CCDC182 Gene

Drugs & Compounds for CCDC182 Gene

No Compound Related Data Available

Transcripts for CCDC182 Gene

mRNA/cDNA for CCDC182 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC182 Gene

No ASD Table

Relevant External Links for CCDC182 Gene

GeneLoc Exon Structure for
CCDC182
ECgene alternative splicing isoforms for
CCDC182

Expression for CCDC182 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC182 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC182 Gene

This gene is overexpressed in Testis (x51.5).

Protein differential expression in normal tissues from HIPED for CCDC182 Gene

This gene is overexpressed in Heart (65.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC182 Gene



Protein tissue co-expression partners for CCDC182 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC182 Gene:

CCDC182

Evidence on tissue expression from TISSUES for CCDC182 Gene

  • Liver(2)
genes like me logo Genes that share expression patterns with CCDC182: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC182 Gene

Orthologs for CCDC182 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC182 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC182 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC182 34
  • 84 (a)
OneToOne
LOC102154847 33
  • 83.88 (n)
cow
(Bos Taurus)
Mammalia CCDC182 34
  • 83 (a)
OneToOne
LOC781808 33
  • 81.58 (n)
mouse
(Mus musculus)
Mammalia 1700106J16Rik 33 34
  • 82.68 (n)
Ccdc182 16
rat
(Rattus norvegicus)
Mammalia Ccdc182 33
  • 81.71 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC182 34
  • 64 (a)
OneToOne
Species where no ortholog for CCDC182 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC182 Gene

ENSEMBL:
Gene Tree for CCDC182 (if available)
TreeFam:
Gene Tree for CCDC182 (if available)

Paralogs for CCDC182 Gene

No data available for Paralogs for CCDC182 Gene

Variants for CCDC182 Gene

Sequence variations from dbSNP and Humsavar for CCDC182 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000147460 -- 57,744,391(+) CTGGG(A/G)AGATC downstream-variant-500B
rs1001741985 -- 57,744,515(+) ACTAT(A/T)CAAAT utr-variant-3-prime
rs1002109337 -- 57,744,867(+) CAGCA(A/G)CAGGT reference, synonymous-codon
rs1003369471 -- 57,746,289(+) AGCAA(C/G)CCAGA upstream-variant-2KB
rs1003809805 -- 57,745,999(+) CATAC(C/T)TGAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CCDC182 Gene

Variant ID Type Subtype PubMed ID
esv2758697 CNV loss 17122850
esv2761967 CNV loss 21179565

Variation tolerance for CCDC182 Gene

Gene Damage Index Score: 10.01; 90.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC182 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC182

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC182 Gene

Disorders for CCDC182 Gene

Relevant External Links for CCDC182

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC182

No disorders were found for CCDC182 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC182 Gene

Publications for CCDC182 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4 60
  2. Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women. (PMID: 22675492) Prescott J … De Vivo I (PloS one 2012) 3 60
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60

Products for CCDC182 Gene

Sources for CCDC182 Gene

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