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Aliases for CCDC181 Gene

Aliases for CCDC181 Gene

  • Coiled-Coil Domain Containing 181 2 3
  • C1orf114 3 4
  • Coiled-Coil Domain-Containing Protein 181 3
  • Chromosome 1 Open Reading Frame 114 2

External Ids for CCDC181 Gene

Previous Symbols for CCDC181 Gene

  • C1orf114

Summaries for CCDC181 Gene

GeneCards Summary for CCDC181 Gene

CCDC181 (Coiled-Coil Domain Containing 181) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC181 Gene

Genomics for CCDC181 Gene

Genomic Location for CCDC181 Gene

Start:
169,394,870 bp from pter
End:
169,460,669 bp from pter
Size:
65,800 bases
Orientation:
Minus strand

Genomic View for CCDC181 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC181 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC181 Gene

No data available for Regulatory Elements for CCDC181 Gene

Proteins for CCDC181 Gene

  • Protein details for CCDC181 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TID7-CC181_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 181
    Protein Accession:
    Q5TID7
    Secondary Accessions:
    • O60780
    • Q53FD5
    • Q5TID9
    • Q8TC48

    Protein attributes for CCDC181 Gene

    Size:
    509 amino acids
    Molecular mass:
    60103 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH26073.1; Type=Frameshift; Positions=370; Evidence={ECO:0000305}; Sequence=CAI19784.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC181 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC181 Gene

Proteomics data for CCDC181 Gene at MOPED

Post-translational modifications for CCDC181 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC181 Gene

No data available for DME Specific Peptides for CCDC181 Gene

Domains for CCDC181 Gene

Protein Domains for CCDC181 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with CCDC181: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC181 Gene

Function for CCDC181 Gene

miRNA for CCDC181 Gene

miRTarBase miRNAs that target CCDC181

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC181 Gene

Localization for CCDC181 Gene

Gene Ontology (GO) - Cellular Components for CCDC181 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with CCDC181: view

Pathways for CCDC181 Gene

SuperPathways for CCDC181 Gene

No Data Available

Interacting Proteins for CCDC181 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000356779%0d%0a9606.ENSP00000337396%0d%0a
Selected Interacting proteins: Q5TID7-CC181_HUMAN ENSP00000356779 for CCDC181 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for CCDC181 Gene

None

No data available for Pathways by source for CCDC181 Gene

Transcripts for CCDC181 Gene

Unigene Clusters for CCDC181 Gene

Coiled-coil domain containing 181:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC181 Gene

No ASD Table

Relevant External Links for CCDC181 Gene

GeneLoc Exon Structure for
CCDC181
ECgene alternative splicing isoforms for
CCDC181

Expression for CCDC181 Gene

mRNA expression in normal human tissues for CCDC181 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC181 Gene

This gene is overexpressed in Testis (5.9) and Pituitary (5.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC181 Gene

SOURCE GeneReport for Unigene cluster for CCDC181 Gene Hs.567557

genes like me logo Genes that share expressions with CCDC181: view

Orthologs for CCDC181 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC181 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C1ORF114 37
  • 99 (a)
OneToOne
CCDC181 36
  • 99.67 (n)
  • 99.41 (a)
cow
(Bos Taurus)
Mammalia CCDC181 36
  • 88.19 (n)
  • 83.46 (a)
CCDC181 37
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC181 36
  • 89.28 (n)
  • 85.6 (a)
CCDC181 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4930455F23Rik 16
Ccdc181 36
  • 79.62 (n)
  • 75.35 (a)
Ccdc181 37
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC181 37
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC181 37
  • 54 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc181 36
  • 79.16 (n)
  • 74.95 (a)
chicken
(Gallus gallus)
Aves C1H1ORF114 36
  • 61.95 (n)
  • 54.14 (a)
CCDC181 37
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC181 37
  • 47 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CCDC181 37
  • 37 (a)
OneToOne
si:ch211-232d19.4 36
  • 52.17 (n)
  • 43.04 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 31 (a)
OneToOne
Species with no ortholog for CCDC181:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC181 Gene

ENSEMBL:
Gene Tree for CCDC181 (if available)
TreeFam:
Gene Tree for CCDC181 (if available)

Paralogs for CCDC181 Gene

Pseudogenes.org Pseudogenes for CCDC181 Gene

genes like me logo Genes that share paralogs with CCDC181: view

No data available for Paralogs for CCDC181 Gene

Variants for CCDC181 Gene

Sequence variations from dbSNP and Humsavar for CCDC181 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs722144 -- 169,458,021(+) TTTTA(A/T)TTAAG intron-variant
rs722145 -- 169,458,244(+) TGCAC(C/T)AACCT intron-variant
rs760603 -- 169,417,012(-) GTATT(A/C)TTCTG intron-variant
rs932301 -- 169,415,661(-) CAAAT(A/G)TCAAA intron-variant
rs961403 -- 169,436,128(+) TAAAC(C/T)CAGGT intron-variant

Relevant External Links for CCDC181 Gene

HapMap Linkage Disequilibrium report
CCDC181

No data available for Structural Variations from Database of Genomic Variants (DGV) for CCDC181 Gene

Disorders for CCDC181 Gene

No disorders were found for CCDC181 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC181 Gene

Publications for CCDC181 Gene

  1. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Functional proteomics mapping of a human signaling pathway. (PMID: 15231748) Colland F. … Gauthier J.M. (Genome Res. 2004) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PMID: 19536175) Ehret G.B. … Chakravarti A. (Eur. J. Hum. Genet. 2009) 3

Products for CCDC181 Gene

Sources for CCDC181 Gene

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