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Aliases for CCDC180 Gene

Aliases for CCDC180 Gene

  • Coiled-Coil Domain Containing 180 2 3
  • KIAA1529 2 3 4
  • Behcets Disease Associated Gene 1 2 3
  • C9orf174 3 4
  • Coiled-Coil Domain-Containing Protein 180 3
  • Chromosome 9 Open Reading Frame 174 2
  • BDAG1 3

External Ids for CCDC180 Gene

Previous HGNC Symbols for CCDC180 Gene

  • KIAA1529
  • C9orf174

Previous GeneCards Identifiers for CCDC180 Gene

  • GC09P100028
  • GC09P100033

Summaries for CCDC180 Gene

GeneCards Summary for CCDC180 Gene

CCDC180 (Coiled-Coil Domain Containing 180) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC180 Gene

Genomics for CCDC180 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC180 Gene

Start:
97,307,304 bp from pter
End:
97,378,524 bp from pter
Size:
71,221 bases
Orientation:
Plus strand

Genomic View for CCDC180 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC180 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC180 Gene

No data available for Regulatory Elements for CCDC180 Gene

Proteins for CCDC180 Gene

  • Protein details for CCDC180 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P1Z9-CC180_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 180
    Protein Accession:
    Q9P1Z9
    Secondary Accessions:
    • Q2KHR6
    • Q5VV25
    • Q68DP5
    • Q69YV9
    • Q6AHY0

    Protein attributes for CCDC180 Gene

    Size:
    1646 amino acids
    Molecular mass:
    191100 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA96053.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAH18175.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC180 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC180 Gene

Proteomics data for CCDC180 Gene at MOPED

Post-translational modifications for CCDC180 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC180 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC180 Gene

Domains for CCDC180 Gene

Protein Domains for CCDC180 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC180: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC180 Gene

Function for CCDC180 Gene

Phenotypes for CCDC180 Gene

GenomeRNAi human phenotypes for CCDC180:
genes like me logo Genes that share phenotypes with CCDC180: view

miRNA for CCDC180 Gene

miRTarBase miRNAs that target CCDC180

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC180 Gene

Localization for CCDC180 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC180 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for CCDC180 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with CCDC180: view

No data available for Subcellular locations from COMPARTMENTS for CCDC180 Gene

Pathways for CCDC180 Gene

SuperPathways for CCDC180 Gene

No Data Available

Interacting Proteins for CCDC180 Gene

Selected Interacting proteins: Q9P1Z9-CC180_HUMAN for CCDC180 Gene via I2D

Symbol External ID(s) Details
HIF1A
UVRAG

Gene Ontology (GO) - Biological Process for CCDC180 Gene

None

No data available for Pathways by source for CCDC180 Gene

Transcripts for CCDC180 Gene

mRNA/cDNA for CCDC180 Gene

(12) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC180 Gene

Coiled-coil domain containing 180:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC180

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC180 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:

ExUns: 25 ^ 26a · 26b ^ 27 ^ 28 ^ 29 ^ 30a · 30b
SP1:
SP2: -
SP3: -
SP4:
SP5:
SP6:
SP7:

Relevant External Links for CCDC180 Gene

GeneLoc Exon Structure for
CCDC180
ECgene alternative splicing isoforms for
CCDC180

Expression for CCDC180 Gene

mRNA expression in normal human tissues for CCDC180 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC180 Gene

This gene is overexpressed in Testis (5.3).

Protein differential expression in normal tissues for CCDC180 Gene

This gene is overexpressed in Brain (53.7) and Nasal epithelium (11.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC180 Gene

SOURCE GeneReport for Unigene cluster for CCDC180 Gene Hs.435629

genes like me logo Genes that share expressions with CCDC180: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for CCDC180 Gene

Orthologs for CCDC180 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC180 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CCDC180 35
  • 81.53 (n)
  • 71.46 (a)
CCDC180 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C11H9orf174 35
  • 81.05 (n)
  • 71.64 (a)
CCDC180 36
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia E230008N13Rik 35
  • 75.65 (n)
  • 67.58 (a)
E230008N13Rik 36
  • 64 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC464596 35
  • 99.08 (n)
  • 98.3 (a)
CCDC180 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc180 35
  • 73.66 (n)
  • 64.88 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC180 36
  • 43 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 45 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
chicken
(Gallus gallus)
Aves C17H9ORF174 35
  • 53.6 (n)
  • 38.97 (a)
CCDC180 36
  • 35 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC180 36
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492567 35
  • 51.13 (n)
  • 38.81 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100538012 35
  • 48.08 (n)
  • 35.7 (a)
CCDC180 36
  • 30 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToOne
Species with no ortholog for CCDC180:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC180 Gene

ENSEMBL:
Gene Tree for CCDC180 (if available)
TreeFam:
Gene Tree for CCDC180 (if available)

Paralogs for CCDC180 Gene

Selected SIMAP similar genes for CCDC180 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for CCDC180 Gene

genes like me logo Genes that share paralogs with CCDC180: view

No data available for Paralogs for CCDC180 Gene

Variants for CCDC180 Gene

Sequence variations from dbSNP and Humsavar for CCDC180 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
VAR_038151 -
VAR_038152 -
VAR_038153 -
VAR_038154 -
VAR_038155 -

Relevant External Links for CCDC180 Gene

HapMap Linkage Disequilibrium report
CCDC180

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC180 Gene

Disorders for CCDC180 Gene

No disorders were found for CCDC180 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CCDC180 Gene

Publications for CCDC180 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10819331) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 3 4
  5. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PMID: 18978678) Vieira A.R. … Marazita M.L. (Genet. Med. 2008) 3

Products for CCDC180 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate CCDC180
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC180
    • Block miRNA regulation of CCDC180 using miScript Target Protectors

    Sources for CCDC180 Gene

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