Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CCDC18 Gene

Aliases for CCDC18 Gene

  • Coiled-Coil Domain Containing 18 2 3 5
  • Sarcoma Antigen NY-SAR-24 3 4
  • Sarcoma Antigen NY-SAR-41 3
  • NY-SAR-41 3

External Ids for CCDC18 Gene

Previous GeneCards Identifiers for CCDC18 Gene

  • GC01P093359
  • GC01P093418
  • GC01P093645
  • GC01P091767

Summaries for CCDC18 Gene

GeneCards Summary for CCDC18 Gene

CCDC18 (Coiled-Coil Domain Containing 18) is a Protein Coding gene. GO annotations related to this gene include nucleotide binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC18 Gene

Genomics for CCDC18 Gene

Regulatory Elements for CCDC18 Gene

Promoters for CCDC18 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC18 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC18 Gene

Chromosome:
1
Start:
93,179,919 bp from pter
End:
93,279,037 bp from pter
Size:
99,119 bases
Orientation:
Plus strand

Genomic View for CCDC18 Gene

Genes around CCDC18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC18 Gene

Proteins for CCDC18 Gene

  • Protein details for CCDC18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T9S5-CCD18_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 18
    Protein Accession:
    Q5T9S5
    Secondary Accessions:
    • Q6ZU17

    Protein attributes for CCDC18 Gene

    Size:
    1454 amino acids
    Molecular mass:
    168962 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC86410.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC18 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC18 Gene

Proteomics data for CCDC18 Gene at MOPED

Post-translational modifications for CCDC18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC18 Gene

Domains & Families for CCDC18 Gene

Protein Domains for CCDC18 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC18: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC18 Gene

Function for CCDC18 Gene

genes like me logo Genes that share phenotypes with CCDC18: view

Animal Model Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC18 Gene

Localization for CCDC18 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC18 Gene COMPARTMENTS Subcellular localization image for CCDC18 gene
Compartment Confidence
cytosol 3
nucleus 3
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC18 Gene

Pathways & Interactions for CCDC18 Gene

SuperPathways for CCDC18 Gene

No Data Available

Interacting Proteins for CCDC18 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000359299%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000359299 for CCDC18 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CCDC18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC18 Gene

Drugs & Compounds for CCDC18 Gene

No Compound Related Data Available

Transcripts for CCDC18 Gene

Unigene Clusters for CCDC18 Gene

Coiled-coil domain containing 18:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC18 Gene

No ASD Table

Relevant External Links for CCDC18 Gene

GeneLoc Exon Structure for
CCDC18
ECgene alternative splicing isoforms for
CCDC18

Expression for CCDC18 Gene

mRNA expression in normal human tissues for CCDC18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC18 Gene

This gene is overexpressed in Testis (x4.5).

Protein differential expression in normal tissues from HIPED for CCDC18 Gene

This gene is overexpressed in Brain (20.8), Plasma (20.4), and Bone marrow mesenchymal stem cell (17.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CCDC18 Gene



SOURCE GeneReport for Unigene cluster for CCDC18 Gene Hs.745125

genes like me logo Genes that share expression patterns with CCDC18: view

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC18 Gene

Orthologs for CCDC18 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC18 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC18 35
  • 99.72 (n)
  • 99.38 (a)
CCDC18 36
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC18 36
  • 89 (a)
OneToOne
LOC540863 35
  • 91.6 (n)
  • 91.03 (a)
dog
(Canis familiaris)
Mammalia CCDC18 35
  • 91.87 (n)
  • 91.17 (a)
CCDC18 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc18 16
Ccdc18 36
  • 84 (a)
OneToOne
Ccdc18 35
  • 86.73 (n)
  • 86.06 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC18 36
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC18 36
  • 31 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc18 35
  • 87.13 (n)
  • 86.39 (a)
chicken
(Gallus gallus)
Aves CCDC18 36
  • 55 (a)
OneToOne
CCDC18 35
  • 65.11 (n)
  • 55.3 (a)
lizard
(Anolis carolinensis)
Reptilia CCDC18 36
  • 53 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia sojo-A 35
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc18 35
  • 56.18 (n)
  • 44.9 (a)
zebrafish
(Danio rerio)
Actinopterygii CCDC18 36
  • 33 (a)
OneToOne
si:dkeyp-1a11.3 35
  • 48.19 (n)
  • 35.87 (a)
Species with no ortholog for CCDC18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC18 Gene

ENSEMBL:
Gene Tree for CCDC18 (if available)
TreeFam:
Gene Tree for CCDC18 (if available)

Paralogs for CCDC18 Gene

genes like me logo Genes that share paralogs with CCDC18: view

No data available for Paralogs for CCDC18 Gene

Variants for CCDC18 Gene

Sequence variations from dbSNP and Humsavar for CCDC18 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs488646 -- 93,257,326(+) AAACC(C/T)TTGGT intron-variant
rs505531 -- 93,212,790(+) gggac(A/G)gggtc intron-variant
rs519723 -- 93,238,769(+) AGCTA(A/G)TTGTA intron-variant
rs558667 -- 93,269,950(+) CTACT(A/G)GAAAT intron-variant
rs512361 -- 93,265,748(+) actgt(C/T)ctaaa intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for CCDC18 Gene

Variant ID Type Subtype PubMed ID
nsv830614 CNV Loss 17160897
nsv830625 CNV Loss 17160897

Relevant External Links for CCDC18 Gene

HapMap Linkage Disequilibrium report
CCDC18
Human Gene Mutation Database (HGMD)
CCDC18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CCDC18 Gene

Disorders for CCDC18 Gene

Relevant External Links for CCDC18

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC18

No disorders were found for CCDC18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC18 Gene

Publications for CCDC18 Gene

  1. Immunomic analysis of human sarcoma. (PMID: 12601173) Lee S.-Y. … Scanlan M.J. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CCDC18 Gene

Sources for CCDC18 Gene

Back to Top

Content