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Aliases for CCDC178 Gene

Aliases for CCDC178 Gene

  • Coiled-Coil Domain Containing 178 2 3
  • C18orf34 3 4
  • Coiled-Coil Domain-Containing Protein 178 3
  • Chromosome 18 Open Reading Frame 34 2

External Ids for CCDC178 Gene

Previous Symbols for CCDC178 Gene

  • C18orf34

Summaries for CCDC178 Gene

GeneCards Summary for CCDC178 Gene

CCDC178 (Coiled-Coil Domain Containing 178) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC178 Gene

Genomics for CCDC178 Gene

Genomic Location for CCDC178 Gene

Start:
32,937,402 bp from pter
End:
33,441,101 bp from pter
Size:
503,700 bases
Orientation:
Minus strand

Genomic View for CCDC178 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC178 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC178 Gene

No data available for Regulatory Elements for CCDC178 Gene

Proteins for CCDC178 Gene

  • Protein details for CCDC178 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5BJE1-CC178_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 178
    Protein Accession:
    Q5BJE1
    Secondary Accessions:
    • A6NDC6
    • J3KS92
    • Q6ZP67
    • Q6ZU20

    Protein attributes for CCDC178 Gene

    Size:
    867 amino acids
    Molecular mass:
    102011 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC85257.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC178 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC178 Gene

Proteomics data for CCDC178 Gene at MOPED

Post-translational modifications for CCDC178 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC178 Gene

Domains for CCDC178 Gene

Protein Domains for CCDC178 Gene

ProtoNet:
genes like me logo Genes that share domains with CCDC178: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC178 Gene

Function for CCDC178 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC178 Gene

Localization for CCDC178 Gene

No data available for Gene Ontology (GO) - Cellular Components for CCDC178 Gene

Pathways for CCDC178 Gene

SuperPathways for CCDC178 Gene

No Data Available

Interacting Proteins for CCDC178 Gene

Gene Ontology (GO) - Biological Process for CCDC178 Gene

None

No data available for Pathways by source for CCDC178 Gene

Transcripts for CCDC178 Gene

Unigene Clusters for CCDC178 Gene

Coiled-coil domain containing 178:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC178 Gene

No ASD Table

Relevant External Links for CCDC178 Gene

GeneLoc Exon Structure for
CCDC178
ECgene alternative splicing isoforms for
CCDC178

Expression for CCDC178 Gene

mRNA expression in normal human tissues for CCDC178 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC178 Gene

This gene is overexpressed in Testis (11.4) and Adipose - Visceral (Omentum) (4.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC178 Gene

SOURCE GeneReport for Unigene cluster for CCDC178 Gene Hs.115461

genes like me logo Genes that share expressions with CCDC178: view

Orthologs for CCDC178 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC178 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC178 36
  • 99.12 (n)
  • 97.81 (a)
CCDC178 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC178 36
  • 77.6 (n)
  • 61.9 (a)
CCDC178 37
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC178 36
  • 82.05 (n)
  • 68.76 (a)
CCDC178 37
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc178 36
  • 66.05 (n)
  • 50.46 (a)
Ccdc178 16
Ccdc178 37
  • 50 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC178 37
  • 28 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC178 37
  • 33 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc178 36
  • 65.19 (n)
  • 50.43 (a)
chicken
(Gallus gallus)
Aves CCDC178 37
  • 38 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC178 37
  • 27 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CCDC178 37
  • 19 (a)
OneToOne
Species with no ortholog for CCDC178:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC178 Gene

ENSEMBL:
Gene Tree for CCDC178 (if available)
TreeFam:
Gene Tree for CCDC178 (if available)

Paralogs for CCDC178 Gene

Selected SIMAP similar genes for CCDC178 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with CCDC178: view

No data available for Paralogs for CCDC178 Gene

Variants for CCDC178 Gene

Sequence variations from dbSNP and Humsavar for CCDC178 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs17357 -- 33,343,225(-) TCAGG(A/G)TCCTC intron-variant
rs149338 -- 33,192,504(+) GGCAT(C/T)GGAGA intron-variant
rs149452 -- 33,222,235(-) ggaag(G/T)aagaa intron-variant
rs156184 -- 33,219,404(-) tgggt(A/C)aaatg intron-variant
rs156185 -- 33,200,410(+) GTGCG(A/G)TGTTT intron-variant

Relevant External Links for CCDC178 Gene

HapMap Linkage Disequilibrium report
CCDC178

No data available for Structural Variations from Database of Genomic Variants (DGV) for CCDC178 Gene

Disorders for CCDC178 Gene

No disorders were found for CCDC178 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC178 Gene

Publications for CCDC178 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PMID: 22219177) Tao S. … Sun J. (Carcinogenesis 2012) 3

Products for CCDC178 Gene

Sources for CCDC178 Gene

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