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Aliases for CCDC177 Gene

Aliases for CCDC177 Gene

  • Coiled-Coil Domain Containing 177 2 3
  • Myelin Proteolipid Protein-Like Protein 2 3 4
  • C14orf162 3 4
  • PLPL 3 4
  • Coiled-Coil Domain-Containing Protein 177 3
  • Chromosome 14 Open Reading Frame 162 2

External Ids for CCDC177 Gene

Previous Symbols for CCDC177 Gene

  • C14orf162

Summaries for CCDC177 Gene

GeneCards Summary for CCDC177 Gene

CCDC177 (Coiled-Coil Domain Containing 177) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC177 Gene

Genomics for CCDC177 Gene

Genomic Location for CCDC177 Gene

Start:
69,569,814 bp from pter
End:
69,574,883 bp from pter
Size:
5,070 bases
Orientation:
Minus strand

Genomic View for CCDC177 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC177 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC177 Gene

No data available for Regulatory Elements for CCDC177 Gene

Proteins for CCDC177 Gene

  • Protein details for CCDC177 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQR7-CC177_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 177
    Protein Accession:
    Q9NQR7
    Secondary Accessions:
    • B2R5G1
    • Q2M359

    Protein attributes for CCDC177 Gene

    Size:
    707 amino acids
    Molecular mass:
    79739 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF86288.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAG35108.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for CCDC177 Gene

Proteomics data for CCDC177 Gene at MOPED

Post-translational modifications for CCDC177 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC177 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC177 Gene

Domains for CCDC177 Gene

Protein Domains for CCDC177 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC177: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC177 Gene

Function for CCDC177 Gene

Phenotypes for CCDC177 Gene

GenomeRNAi human phenotypes for CCDC177:
genes like me logo Genes that share phenotypes with CCDC177: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC177 Gene

Localization for CCDC177 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCDC177 Gene

Pathways for CCDC177 Gene

SuperPathways for CCDC177 Gene

No Data Available

Interacting Proteins for CCDC177 Gene

Gene Ontology (GO) - Biological Process for CCDC177 Gene

None

No data available for Pathways by source for CCDC177 Gene

Transcripts for CCDC177 Gene

mRNA/cDNA for CCDC177 Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC177 Gene

Coiled-coil domain containing 177:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC177 Gene

No ASD Table

Relevant External Links for CCDC177 Gene

GeneLoc Exon Structure for
CCDC177
ECgene alternative splicing isoforms for
CCDC177

Expression for CCDC177 Gene

mRNA expression in normal human tissues for CCDC177 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC177 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (10.1), Brain - Cerebellum (9.2), Brain - Cortex (6.1), Brain - Frontal Cortex (BA9) (5.9), and Brain - Anterior cingulate cortex (BA24) (4.9).

SOURCE GeneReport for Unigene cluster for CCDC177 Gene Hs.458319

genes like me logo Genes that share expressions with CCDC177: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for CCDC177 Gene

Orthologs for CCDC177 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC177 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC101057527 35
  • 99.17 (n)
  • 99.46 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 94 (a)
OneToOne
CCDC177 35
  • 88.83 (n)
  • 93.12 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 92 (a)
OneToOne
CCDC177 35
  • 88.02 (n)
  • 90.58 (a)
mouse
(Mus musculus)
Mammalia Ccdc177 35
  • 84.97 (n)
  • 90.04 (a)
Ccdc177 36
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc177 35
  • 85 (n)
  • 90.74 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 59 (a)
OneToOne
CCDC177 35
  • 61.72 (n)
  • 57.53 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 55 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ccdc177 35
  • 54.33 (n)
  • 53.06 (a)
ccdc177 36
  • 48 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3120 36
  • 17 (a)
OneToOne
Species with no ortholog for CCDC177:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC177 Gene

ENSEMBL:
Gene Tree for CCDC177 (if available)
TreeFam:
Gene Tree for CCDC177 (if available)

Paralogs for CCDC177 Gene

No data available for Paralogs for CCDC177 Gene

Variants for CCDC177 Gene

Sequence variations from dbSNP and Humsavar for CCDC177 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs4048622 -- 69,573,107(+) gcggc(-/GGCGGC)CGCGG cds-indel
rs4899302 -- 69,574,770(+) TCCCT(A/G)AAATA utr-variant-5-prime
rs4902734 -- 69,573,164(+) ATGCG(C/G)TCGCG missense, reference
rs4902735 -- 69,575,747(+) ACAGA(C/T)CGGAG upstream-variant-2KB
rs6573892 -- 69,573,506(+) GAGGA(A/G)GCTGC synonymous-codon, reference

Relevant External Links for CCDC177 Gene

HapMap Linkage Disequilibrium report
CCDC177

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC177 Gene

Disorders for CCDC177 Gene

No disorders were found for CCDC177 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC177 Gene

Publications for CCDC177 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. 2',3'-cyclic nucleotide 3'-phosphodiesterase: a novel candidate autoantigen in demyelinating diseases. (PMID: 9143234) RAPsener M. … Martin R. (J. Neuroimmunol. 1997) 23
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CCDC177 Gene

Sources for CCDC177 Gene

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