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Aliases for CCDC175 Gene

Aliases for CCDC175 Gene

  • Coiled-Coil Domain Containing 175 2 3 5
  • C14orf38 3 4
  • Coiled-Coil Domain-Containing Protein 175 3
  • Chromosome 14 Open Reading Frame 38 2
  • C14_5395 3

External Ids for CCDC175 Gene

Previous HGNC Symbols for CCDC175 Gene

  • C14orf38

Previous GeneCards Identifiers for CCDC175 Gene

  • GC14M059971

Summaries for CCDC175 Gene

GeneCards Summary for CCDC175 Gene

CCDC175 (Coiled-Coil Domain Containing 175) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC175 Gene

Genomics for CCDC175 Gene

Regulatory Elements for CCDC175 Gene

Enhancers for CCDC175 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F059529 0.2 ENCODE 20.4 +52.7 52669 0.8 L3HYPDH CCDC175 JKAMP ENSG00000258782
GH14F059507 1.1 ENCODE 13.1 +74.4 74429 1.2 SCRT1 CTCF ZNF654 TRIM22 RAD21 NR2F2 GATA3 JUND KLF16 GATA2 L3HYPDH CCDC175 JKAMP ENSG00000258782
GH14F059510 0.2 ENCODE 13.1 +70.5 70452 2.4 CTCF ZNF654 HLF ZIC2 ZNF652 ZNF2 RAD21 L3HYPDH CCDC175 JKAMP ENSG00000258782
GH14F059621 0.4 ENCODE 11 -40.5 -40544 1.4 HLF L3HYPDH CCDC175 MIR5586 GC14M059571
GH14F059582 1 Ensembl ENCODE 7.3 -1.4 -1397 1.4 CTCF PKNOX1 INSM2 FEZF1 ZNF843 ZKSCAN1 OSR2 ZSCAN16 ZNF600 ZNF24 L3HYPDH CCDC175 GC14M059571
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around CCDC175 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC175 Gene

59,504,539 bp from pter
59,582,114 bp from pter
77,576 bases
Minus strand

Genomic View for CCDC175 Gene

Genes around CCDC175 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC175 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC175 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC175 Gene

Proteins for CCDC175 Gene

  • Protein details for CCDC175 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 175
    Protein Accession:
    Secondary Accessions:
    • G3V5J7

    Protein attributes for CCDC175 Gene

    793 amino acids
    Molecular mass:
    93626 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC175 Gene

Post-translational modifications for CCDC175 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC175 Gene

No data available for DME Specific Peptides for CCDC175 Gene

Domains & Families for CCDC175 Gene

Protein Domains for CCDC175 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC175: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC175 Gene

Function for CCDC175 Gene

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC175 Gene

Localization for CCDC175 Gene

Subcellular locations from

Jensen Localization Image for CCDC175 Gene COMPARTMENTS Subcellular localization image for CCDC175 gene
Compartment Confidence
cytosol 3
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC175 Gene

Pathways & Interactions for CCDC175 Gene

SuperPathways for CCDC175 Gene

No Data Available

Interacting Proteins for CCDC175 Gene

Gene Ontology (GO) - Biological Process for CCDC175 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC175 Gene

Transcripts for CCDC175 Gene

mRNA/cDNA for CCDC175 Gene

(7) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC175 Gene

Coiled-coil domain containing 175:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC175 Gene

No ASD Table

Relevant External Links for CCDC175 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC175 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCDC175 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC175 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x11.3) and Brain - Cerebellum (x10.8).

Protein differential expression in normal tissues from HIPED for CCDC175 Gene

This gene is overexpressed in Plasma (54.9) and CD8 Tcells (12.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC175 Gene

Protein tissue co-expression partners for CCDC175 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CCDC175 Gene:


SOURCE GeneReport for Unigene cluster for CCDC175 Gene:

genes like me logo Genes that share expression patterns with CCDC175: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC175 Gene

Orthologs for CCDC175 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC175 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CCDC175 34 35
  • 99.08 (n)
(Canis familiaris)
Mammalia CCDC175 34 35
  • 77.9 (n)
(Bos Taurus)
Mammalia CCDC175 34 35
  • 77.5 (n)
(Rattus norvegicus)
Mammalia Ccdc175 34
  • 68.01 (n)
(Mus musculus)
Mammalia Ccdc175 34 16 35
  • 66.97 (n)
(Monodelphis domestica)
Mammalia CCDC175 35
  • 33 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC175 35
  • 26 (a)
(Gallus gallus)
Aves CCDC175 35
  • 25 (a)
(Danio rerio)
Actinopterygii ccdc175 35
  • 20 (a)
Species where no ortholog for CCDC175 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC175 Gene

Gene Tree for CCDC175 (if available)
Gene Tree for CCDC175 (if available)

Paralogs for CCDC175 Gene

No data available for Paralogs for CCDC175 Gene

Variants for CCDC175 Gene

Sequence variations from dbSNP and Humsavar for CCDC175 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1010648 -- 59,521,120(-) atgtg(A/G)atctc intron-variant, downstream-variant-500B
rs10132300 -- 59,559,585(+) TCTTA(G/T)AGAAA intron-variant
rs10132560 -- 59,511,114(+) GAAGA(G/T)ATTCA intron-variant
rs10133242 -- 59,526,371(+) GAGGC(C/T)GAGGC intron-variant
rs10134312 -- 59,551,584(+) aagta(C/G)cgggt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC175 Gene

Variant ID Type Subtype PubMed ID
esv2658502 CNV deletion 23128226
esv3353735 CNV insertion 20981092

Variation tolerance for CCDC175 Gene

Gene Damage Index Score: 5.07; 68.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC175 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC175 Gene

Disorders for CCDC175 Gene

Relevant External Links for CCDC175

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC175 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC175 Gene

Publications for CCDC175 Gene

  1. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4 64
  2. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 64

Products for CCDC175 Gene

Sources for CCDC175 Gene

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