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Aliases for CCDC173 Gene

Aliases for CCDC173 Gene

  • Coiled-Coil Domain Containing 173 2 3 5
  • C2orf77 3 4
  • Chromosome 2 Open Reading Frame 77 2
  • Hypothetical LOC129881 2

External Ids for CCDC173 Gene

Previous HGNC Symbols for CCDC173 Gene

  • C2orf77

Previous GeneCards Identifiers for CCDC173 Gene

  • GC02M170502

Summaries for CCDC173 Gene

GeneCards Summary for CCDC173 Gene

CCDC173 (Coiled-Coil Domain Containing 173) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC173 Gene

Genomics for CCDC173 Gene

Regulatory Elements for CCDC173 Gene

Enhancers for CCDC173 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC173 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC173 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC173 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC173 Gene

169,645,425 bp from pter
169,694,433 bp from pter
49,009 bases
Minus strand

Genomic View for CCDC173 Gene

Genes around CCDC173 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC173 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC173 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC173 Gene

Proteins for CCDC173 Gene

  • Protein details for CCDC173 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 173
    Protein Accession:
    Secondary Accessions:
    • Q6PJF6

    Protein attributes for CCDC173 Gene

    552 amino acids
    Molecular mass:
    66403 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI17446.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for CCDC173 Gene

Proteomics data for CCDC173 Gene at MOPED

Post-translational modifications for CCDC173 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC173 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC173 Gene

Domains & Families for CCDC173 Gene

Protein Domains for CCDC173 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC173: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC173 Gene

Function for CCDC173 Gene

Phenotypes for CCDC173 Gene

GenomeRNAi human phenotypes for CCDC173:
genes like me logo Genes that share phenotypes with CCDC173: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC173 Gene

Localization for CCDC173 Gene

Subcellular locations from

Jensen Localization Image for CCDC173 Gene COMPARTMENTS Subcellular localization image for CCDC173 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC173 Gene

Pathways & Interactions for CCDC173 Gene

SuperPathways for CCDC173 Gene

No Data Available

Interacting Proteins for CCDC173 Gene

Gene Ontology (GO) - Biological Process for CCDC173 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC173 Gene

Drugs & Compounds for CCDC173 Gene

No Compound Related Data Available

Transcripts for CCDC173 Gene

Unigene Clusters for CCDC173 Gene

Coiled-coil domain containing 173:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC173 Gene

No ASD Table

Relevant External Links for CCDC173 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC173 Gene

mRNA expression in normal human tissues for CCDC173 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC173 Gene

This gene is overexpressed in Testis (x31.2).

Protein differential expression in normal tissues from HIPED for CCDC173 Gene

This gene is overexpressed in Blymphocyte (35.8) and Monocytes (19.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC173 Gene

SOURCE GeneReport for Unigene cluster for CCDC173 Gene Hs.370111

genes like me logo Genes that share expression patterns with CCDC173: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC173 Gene

Orthologs for CCDC173 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC173 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC173 35
  • 90.74 (n)
  • 87.39 (a)
CCDC173 36
  • 86 (a)
(Canis familiaris)
Mammalia CCDC173 35
  • 90.93 (n)
  • 88.38 (a)
CCDC173 36
  • 86 (a)
(Mus musculus)
Mammalia Ccdc173 35
  • 81.32 (n)
  • 75.46 (a)
Ccdc173 16
Ccdc173 36
  • 75 (a)
(Pan troglodytes)
Mammalia CCDC173 35
  • 99.46 (n)
  • 98.55 (a)
CCDC173 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc173 35
  • 82.78 (n)
  • 75.82 (a)
(Monodelphis domestica)
Mammalia CCDC173 36
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC173 36
  • 54 (a)
(Gallus gallus)
Aves LOC101749600 35
  • 59.82 (n)
  • 45.65 (a)
CCDC173 36
  • 43 (a)
(Anolis carolinensis)
Reptilia CCDC173 36
  • 40 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc173 35
  • 54.22 (n)
  • 41.96 (a)
(Danio rerio)
Actinopterygii ccdc173 35
  • 50.09 (n)
  • 37.94 (a)
ccdc173 36
  • 35 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
Species with no ortholog for CCDC173:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC173 Gene

Gene Tree for CCDC173 (if available)
Gene Tree for CCDC173 (if available)

Paralogs for CCDC173 Gene

No data available for Paralogs for CCDC173 Gene

Variants for CCDC173 Gene

Sequence variations from dbSNP and Humsavar for CCDC173 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1596932 -- 169,666,708(-) attac(A/G)tacta intron-variant
rs1838902 -- 169,675,509(-) GTGTA(C/G)CACCT intron-variant
rs1900380 -- 169,667,618(-) ataac(A/G)tccat intron-variant
rs1900381 -- 169,667,237(-) ctctt(A/G)aaccc intron-variant
rs1058345 -- 169,686,616(-) agaga(C/T)ctgag intron-variant

Variation tolerance for CCDC173 Gene

Residual Variation Intolerance Score: 95.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.65; 78.36% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CCDC173 Gene

Disorders for CCDC173 Gene

Relevant External Links for CCDC173

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC173 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC173 Gene

Publications for CCDC173 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  3. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for CCDC173 Gene

Sources for CCDC173 Gene