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Aliases for CCDC171 Gene

Aliases for CCDC171 Gene

  • Coiled-Coil Domain Containing 171 2 3
  • Myosin Tail Domain Containing Protein 2 3
  • C9orf93 3 4
  • Chromosome 9 Open Reading Frame 93 2
  • BA536D16.1 3
  • BA778P13.1 3

External Ids for CCDC171 Gene

Previous HGNC Symbols for CCDC171 Gene

  • C9orf93

Summaries for CCDC171 Gene

GeneCards Summary for CCDC171 Gene

CCDC171 (Coiled-Coil Domain Containing 171) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and signal transducer activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC171 Gene

Genomics for CCDC171 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC171 Gene

Chromosome:
9
Start:
15,552,874 bp from pter
End:
16,061,663 bp from pter
Size:
508,790 bases
Orientation:
Plus strand

Genomic View for CCDC171 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for CCDC171 Gene

No data available for Regulatory Elements for CCDC171 Gene

Proteins for CCDC171 Gene

  • Protein details for CCDC171 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6TFL3-CC171_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 171
    Protein Accession:
    Q6TFL3
    Secondary Accessions:
    • B7ZM22
    • Q5SU58
    • Q6P1W1
    • Q6ZR13
    • Q8N1Z4
    • Q8N8L3
    • Q8TBR2

    Protein attributes for CCDC171 Gene

    Size:
    1326 amino acids
    Molecular mass:
    152810 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04370.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC04823.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC87511.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC171 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC171 Gene

Proteomics data for CCDC171 Gene at MOPED

Post-translational modifications for CCDC171 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC171 Gene

No data available for DME Specific Peptides for CCDC171 Gene

Domains & Families for CCDC171 Gene

Protein Domains for CCDC171 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC171 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC171: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC171 Gene

Function for CCDC171 Gene

genes like me logo Genes that share phenotypes with CCDC171: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC171

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC171 Gene

Localization for CCDC171 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC171 Gene COMPARTMENTS Subcellular localization image for CCDC171 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC171 Gene

Pathways & Interactions for CCDC171 Gene

SuperPathways for CCDC171 Gene

No Data Available

Interacting Proteins for CCDC171 Gene

Gene Ontology (GO) - Biological Process for CCDC171 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC171 Gene

Drugs & Compounds for CCDC171 Gene

No Compound Related Data Available

Transcripts for CCDC171 Gene

Unigene Clusters for CCDC171 Gene

Coiled-coil domain containing 171:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC171

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC171 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22 ^ 23a · 23b ^
SP1: -
SP2: -
SP3:
SP4:

ExUns: 24 ^ 25a · 25b ^ 26 ^ 27a · 27b
SP1: -
SP2:
SP3:
SP4: - - -

Relevant External Links for CCDC171 Gene

GeneLoc Exon Structure for
CCDC171
ECgene alternative splicing isoforms for
CCDC171

Expression for CCDC171 Gene

mRNA expression in normal human tissues for CCDC171 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC171 Gene

This gene is overexpressed in Testis (x6.1).

Protein differential expression in normal tissues from HIPED for CCDC171 Gene

This gene is overexpressed in Lung (33.4), Brain (21.2), and Pancreas (10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC171 Gene



SOURCE GeneReport for Unigene cluster for CCDC171 Gene Hs.17267

genes like me logo Genes that share expression patterns with CCDC171: view

Protein tissue co-expression partners for CCDC171 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC171 Gene

Orthologs for CCDC171 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC171 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CCDC171 35
  • 92.15 (n)
  • 91.4 (a)
CCDC171 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC171 35
  • 92.83 (n)
  • 92.73 (a)
CCDC171 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc171 35
  • 85.22 (n)
  • 87.29 (a)
Ccdc171 16
Ccdc171 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CCDC171 35
  • 99.4 (n)
  • 98.87 (a)
CCDC171 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1560884 35
  • 85.2 (n)
  • 86.03 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC171 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC171 36
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves C9ORF93 35
  • 72.97 (n)
  • 63.54 (a)
CCDC171 36
  • 62 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC171 36
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc171 35
  • 59.1 (n)
  • 46.61 (a)
Str.18178 35
zebrafish
(Danio rerio)
Actinopterygii si:ch211-116m6.4 35
  • 49.39 (n)
  • 38.99 (a)
CCDC171 36
  • 32 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 27 (a)
OneToOne
Species with no ortholog for CCDC171:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC171 Gene

ENSEMBL:
Gene Tree for CCDC171 (if available)
TreeFam:
Gene Tree for CCDC171 (if available)

Paralogs for CCDC171 Gene

(3) SIMAP similar genes for CCDC171 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with CCDC171: view

No data available for Paralogs for CCDC171 Gene

Variants for CCDC171 Gene

Sequence variations from dbSNP and Humsavar for CCDC171 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs169342 -- 15,613,840(-) tcatt(A/T)gaaaa intron-variant
rs175762 -- 15,581,331(-) caata(C/T)tgatt intron-variant
rs183928 -- 15,611,508(-) GAGAC(G/T)GAAAG intron-variant
rs185693 -- 15,554,105(-) gaggc(A/G)gagct intron-variant
rs192465 -- 15,582,783(-) cacct(C/T)ctgcc intron-variant

Variation tolerance for CCDC171 Gene

Residual Variation Intolerance Score: 28.69% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 18.75; 98.67% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC171 Gene

HapMap Linkage Disequilibrium report
CCDC171

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC171 Gene

Disorders for CCDC171 Gene

Relevant External Links for CCDC171

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC171
genes like me logo Genes that share disorders with CCDC171: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC171 Gene

Publications for CCDC171 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for CCDC171 Gene

Sources for CCDC171 Gene

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