Aliases for CCDC17 Gene
External Ids for CCDC17 Gene
- HGNC: 26574
- Entrez Gene: 149483
- Ensembl: ENSG00000159588
- UniProtKB: Q96LX7
Previous GeneCards Identifiers for CCDC17 Gene
- GC01M045755
- GC01M045858
- GC01M046086
- GC01M044196
Summaries for CCDC17 Gene
GeneCards Summary for CCDC17 Gene
CCDC17 (Coiled-Coil Domain Containing 17) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC17 Gene
Genomics for CCDC17 Gene
Regulatory Elements for CCDC17 Gene
Enhancers for CCDC17 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CCDC17 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CCDC17 gene promoter:
Regulatory Element Products
Genomic Location for CCDC17 Gene
- Chromosome:
- 1
- Start:
- 45,620,044 bp from pter
- End:
- 45,624,787 bp from pter
- Size:
- 4,744 bases
- Orientation:
- Minus strand
Genomic View for CCDC17 Gene
Genes around CCDC17 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p34.1 by Ensembl
- 1p34.1 by Entrez Gene
- 1p34.1 by HGNC
CCDC17 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCDC17 Gene
Proteins for CCDC17 Gene
-
Protein details for CCDC17 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96LX7-CCD17_HUMAN
- Recommended name:
- Coiled-coil domain-containing protein 17
- Protein Accession:
- Q96LX7
- A1A4Y7
- B4DNX7
- B4E1Q5
- C9J8L2
- Q0P683
- Q5T629
Protein attributes for CCDC17 Gene
- Size:
- 622 amino acids
- Molecular mass:
- 67721 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAB71539.1; Type=Miscellaneous discrepancy; Note=Incompletely spliced mRNA.; Evidence={ECO:0000305};
Protein Expression for CCDC17 Gene
Post-translational modifications for CCDC17 Gene
Other Protein References for CCDC17 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CCDC17
- Novus Biologicals Antibodies for CCDC17
- Invitrogen Antibodies for CCDC17
- GeneTex CCDC17 antibody for CCDC17
Protein Products
-
OriGene Purified Proteins for CCDC17
- Search Origene for MassSpec and Protein Over-expression Lysates for CCDC17
- Origene Custom Protein Services for CCDC17
- Search GeneTex for Proteins for CCDC17
Assay Products
No data available for DME Specific Peptides for CCDC17 Gene
Domains & Families for CCDC17 Gene
Protein Domains for CCDC17 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for CCDC17 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC17 Gene
Function for CCDC17 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for CCDC17 Gene
- GenomeRNAi human phenotypes for CCDC17:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC17
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC17 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC17 gene
- Search ViGene Biosciences for CCDC17
CRISPR Products
-
OriGene CRISPR knockouts for CCDC17
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC17
miRNA Products
- Search ViGene Biosciences for CCDC17
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCDC17
- Browse OriGene Inhibitory RNA Products For CCDC17
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC17 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCDC17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC17
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CCDC17
-
ViGene Biosciences adenoviral particle packaged cDNA for CCDC17 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC17 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC17 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC17 Gene
Localization for CCDC17 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| peroxisome | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC17 Gene
Transcripts for CCDC17 Gene
mRNA/cDNA for CCDC17 Gene
- (15) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (25) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCDC17 Gene
- Coiled-coil domain containing 17:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for CCDC17
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC17
miRNA Products
- Search ViGene Biosciences for CCDC17
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCDC17
- Browse OriGene Inhibitory RNA Products For CCDC17
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC17 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCDC17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC17
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||
| SP4: |
Expression for CCDC17 Gene
mRNA differential expression in normal tissues according to GTEx for CCDC17 Gene
This gene is overexpressed in Fallopian Tube (x11.5), Cervix - Endocervix (x6.2), Whole Blood (x4.5), and Lung (x4.1).
This gene is overexpressed in Nasal epithelium (68.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC17 Gene
NURSA nuclear receptor signaling pathways regulating expression of CCDC17 Gene:
CCDC17SOURCE GeneReport for Unigene cluster for CCDC17 Gene:
Hs.18912Primer Products
-
OriGene qPCR primer pairs for CCDC17
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC17 Gene
Orthologs for CCDC17 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCDC17 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CCDC17 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CCDC17 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Ccdc17 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccdc17 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCDC17 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CCDC17 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CCDC17 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | CR854855.2 35 |
|
OneToOne |
- Species where no ortholog for CCDC17 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CCDC17 Gene
No data available for Paralogs for CCDC17 Gene
Variants for CCDC17 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000179916 | -- | 45,626,680(+) | GGTCA(C/T)TGTGT | upstream-variant-2KB | |
| rs1001030214 | -- | 45,624,752(+) | GTCTC(A/C/G)CTGTC | nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime | |
| rs1001558243 | -- | 45,622,527(+) | CCGCT(C/G)GCGAG | intron-variant | |
| rs1001630531 | -- | 45,622,300(+) | GCCGG(A/T)TTTCA | intron-variant, nc-transcript-variant, reference, missense | |
| rs1002172613 | -- | 45,624,973(+) | CGCCT(C/T)GGCCT | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3585911 | CNV | gain | 21293372 |
| esv3893512 | CNV | gain | 25118596 |
| nsv822509 | CNV | loss | 20364138 |
| nsv829726 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
81.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.74;
57.76% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CCDC17 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCDC17
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC17 Gene
Disorders for CCDC17 Gene
Relevant External Links for CCDC17
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CCDC17
No disorders were found for CCDC17 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC17 Gene
Publications for CCDC17 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
- A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
Products for CCDC17 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CCDC17
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CCDC17
- Search Origene for MassSpec and Protein Over-expression Lysates for CCDC17
- Origene Custom Protein Services for CCDC17
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCDC17
- Browse OriGene Inhibitory RNA Products For CCDC17
- OriGene qPCR primer pairs for CCDC17
- OriGene CRISPR knockouts for CCDC17
- OriGene ORF clones in human for CCDC17
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CCDC17
- GenScript: Next-day shipping cDNA ORF clone for CCDC17 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CCDC17
- GenScript Custom Assay Services for CCDC17
- GenScript Custom overexpressing Cell Line Services for CCDC17
- Browse GenScript CRISPR for CCDC17
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CCDC17
- Novus Biologicals proteins and lysates for CCDC17
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for CCDC17 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCDC17 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCDC17 gene
- Search ViGene Biosciences for CCDC17
- Horizon Cell Lines for CCDC17
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC17
- VectorBuilder custom plasmid, inducible vectors for CCDC17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC17
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CCDC17 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer