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Aliases for CCDC17 Gene

Aliases for CCDC17 Gene

  • Coiled-Coil Domain Containing 17 2 3 5

External Ids for CCDC17 Gene

Previous GeneCards Identifiers for CCDC17 Gene

  • GC01M045755
  • GC01M045858
  • GC01M046086
  • GC01M044196

Summaries for CCDC17 Gene

GeneCards Summary for CCDC17 Gene

CCDC17 (Coiled-Coil Domain Containing 17) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC17 Gene

Genomics for CCDC17 Gene

Regulatory Elements for CCDC17 Gene

Enhancers for CCDC17 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F045657 0.7 ENCODE 12.4 -33.6 -33598 1.5 ELF3 ATF1 ARID4B RAD21 RARA YY1 ZNF121 MIXL1 THAP11 HMG20B MAST2 GPBP1L1 CCDC17 IPP ZSWIM5 RPL7AP16 TMEM69
GH01F045590 0.8 ENCODE 12.1 +33.6 33649 0.7 SCRT1 ZNF362 GATA3 POLR2A SCRT2 CCDC17 GPBP1L1 IPP ENSG00000281112 GC01M045583
GH01F045582 0.6 ENCODE 12.1 +39.9 39938 5.4 HDGF PKNOX1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 CCDC163 GPBP1L1 ZSWIM5 TOE1 CCDC17 LURAP1 RPS8 PTCH2 IPP MAST2
GH01F045514 0.2 ENCODE 10.8 +109.1 109124 2.2 PAF1 ZNF766 CEBPA KLF9 ZNF7 CCDC163 AKR1A1 CCDC17 GPBP1L1 MMACHC PIR60929 PRDX1
GH01F045822 0.6 ENCODE 10.4 -198.0 -197965 0.8 SOX13 ELF3 SAP130 TAL1 ARID4B RAD21 ZNF644 TEAD3 FOSL1 ZBTB48 MAST2 TMEM69 GPBP1L1 CCDC17 TMA16P2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around CCDC17 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC17 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001744508 1887 201 SSRP1 ZBTB33

Genomic Location for CCDC17 Gene

Chromosome:
1
Start:
45,620,044 bp from pter
End:
45,624,787 bp from pter
Size:
4,744 bases
Orientation:
Minus strand

Genomic View for CCDC17 Gene

Genes around CCDC17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC17 Gene

Proteins for CCDC17 Gene

  • Protein details for CCDC17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LX7-CCD17_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 17
    Protein Accession:
    Q96LX7
    Secondary Accessions:
    • A1A4Y7
    • B4DNX7
    • B4E1Q5
    • C9J8L2
    • Q0P683
    • Q5T629

    Protein attributes for CCDC17 Gene

    Size:
    622 amino acids
    Molecular mass:
    67721 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB71539.1; Type=Miscellaneous discrepancy; Note=Incompletely spliced mRNA.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC17 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC17 Gene

Post-translational modifications for CCDC17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC17 Gene

Domains & Families for CCDC17 Gene

Protein Domains for CCDC17 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC17: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC17 Gene

Function for CCDC17 Gene

Gene Ontology (GO) - Molecular Function for CCDC17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC17: view
genes like me logo Genes that share phenotypes with CCDC17: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC17 Gene

Localization for CCDC17 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC17 Gene COMPARTMENTS Subcellular localization image for CCDC17 gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC17 Gene

Pathways & Interactions for CCDC17 Gene

SuperPathways for CCDC17 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC17 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC17 Gene

Transcripts for CCDC17 Gene

Unigene Clusters for CCDC17 Gene

Coiled-coil domain containing 17:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC17 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b
SP1: -
SP2: -
SP3: - -
SP4:

Relevant External Links for CCDC17 Gene

GeneLoc Exon Structure for
CCDC17
ECgene alternative splicing isoforms for
CCDC17

Expression for CCDC17 Gene

mRNA expression in normal human tissues for CCDC17 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC17 Gene

This gene is overexpressed in Fallopian Tube (x11.5), Cervix - Endocervix (x6.2), Whole Blood (x4.5), and Lung (x4.1).

Protein differential expression in normal tissues from HIPED for CCDC17 Gene

This gene is overexpressed in Nasal epithelium (68.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC17 Gene



Protein tissue co-expression partners for CCDC17 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC17 Gene:

CCDC17

SOURCE GeneReport for Unigene cluster for CCDC17 Gene:

Hs.18912
genes like me logo Genes that share expression patterns with CCDC17: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC17 Gene

Orthologs for CCDC17 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC17 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC17 34 35
  • 99.14 (n)
cow
(Bos Taurus)
Mammalia CCDC17 34 35
  • 80.08 (n)
dog
(Canis familiaris)
Mammalia CCDC17 34 35
  • 78.59 (n)
mouse
(Mus musculus)
Mammalia Ccdc17 34 16 35
  • 71.62 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc17 34
  • 71.51 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC17 35
  • 47 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC17 35
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC17 35
  • 42 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CR854855.2 35
  • 27 (a)
OneToOne
Species where no ortholog for CCDC17 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC17 Gene

ENSEMBL:
Gene Tree for CCDC17 (if available)
TreeFam:
Gene Tree for CCDC17 (if available)

Paralogs for CCDC17 Gene

No data available for Paralogs for CCDC17 Gene

Variants for CCDC17 Gene

Sequence variations from dbSNP and Humsavar for CCDC17 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111690844 -- 45,626,482(+) CAGGC(A/G)CCCGC upstream-variant-2KB
rs111824448 -- 45,621,981(+) GAGTC(A/G)CAGAT intron-variant, nc-transcript-variant, reference, stop-gained
rs112037003 -- 45,622,230(+) TGGGG(C/T)GCTCA intron-variant
rs112139251 -- 45,620,778(+) GTGTC(C/T)GTACA nc-transcript-variant, reference, missense
rs112292664 -- 45,623,613(+) GCCCT(A/G)GGGTT intron-variant, nc-transcript-variant, reference, stop-gained, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for CCDC17 Gene

Variant ID Type Subtype PubMed ID
esv3585911 CNV gain 21293372
esv3893512 CNV gain 25118596
nsv822509 CNV loss 20364138
nsv829726 CNV loss 17160897

Variation tolerance for CCDC17 Gene

Residual Variation Intolerance Score: 81.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.74; 57.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC17 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC17

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC17 Gene

Disorders for CCDC17 Gene

Relevant External Links for CCDC17

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC17

No disorders were found for CCDC17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC17 Gene

Publications for CCDC17 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for CCDC17 Gene

Sources for CCDC17 Gene

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