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Aliases for CCDC169 Gene

Aliases for CCDC169 Gene

  • Coiled-Coil Domain Containing 169 2 3 5
  • C13orf38 3 4
  • Coiled-Coil Domain-Containing Protein 169 3
  • Chromosome 13 Open Reading Frame 38 2
  • RP11-251J8.1 3

External Ids for CCDC169 Gene

Previous HGNC Symbols for CCDC169 Gene

  • C13orf38

Previous GeneCards Identifiers for CCDC169 Gene

  • GC13M036802

Summaries for CCDC169 Gene

GeneCards Summary for CCDC169 Gene

CCDC169 (Coiled-Coil Domain Containing 169) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC169 Gene

Genomics for CCDC169 Gene

Regulatory Elements for CCDC169 Gene

Enhancers for CCDC169 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13G036343 1.3 ENCODE dbSUPER 13.3 -47.7 -47710 4.1 HDGF PKNOX1 FOXA2 CREB3L1 SIN3A ARID4B DMAP1 FEZF1 ZNF2 YY1 SOHLH2 SPG20 CCDC169 RFXAP SPG20-AS1 CCDC169-SOHLH2
GH13G036154 1.3 FANTOM5 Ensembl ENCODE dbSUPER 11.2 +142.8 142839 1.8 POLR2A SMARCA4 PRDM4 DCLK1 CCDC169 SOHLH2 SPG20
GH13G036130 1.1 ENCODE dbSUPER 12.4 +166.2 166205 2.7 ZSCAN4 SIN3A ZNF121 GLIS2 ZNF366 FOS EGR2 ZNF263 SP3 ZNF398 SOHLH2 CCDC169 DCLK1 NMTRQ-TTG10-1
GH13G036296 1 ENCODE 12.8 -1.2 -1185 4.3 PKNOX1 ATF1 FEZF1 GLI4 BRCA1 ZNF2 GLIS2 FOS KLF13 SP3 SOHLH2 CCDC169 CCDC169-SOHLH2 SPG20-AS1
GH13G036156 0.9 ENCODE dbSUPER 11.3 +139.7 139741 3.0 CEBPB KLF17 FEZF1 EP300 ATF2 PRDM6 JUND MAFF ZNF366 SMARCA4 DCLK1 CCDC169 SOHLH2 RNU6-71P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC169 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC169 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000061287 155 1401 PKNOX1 ATF1 FEZF1 GLI4 BRCA1 ZNF2 GLIS2 FOS KLF13 SP3

Genomic Location for CCDC169 Gene

Chromosome:
13
Start:
36,222,008 bp from pter
End:
36,297,855 bp from pter
Size:
75,848 bases
Orientation:
Minus strand

Genomic View for CCDC169 Gene

Genes around CCDC169 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC169 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC169 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC169 Gene

Proteins for CCDC169 Gene

  • Protein details for CCDC169 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NNP5-CC169_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 169
    Protein Accession:
    A6NNP5
    Secondary Accessions:
    • A6NC13
    • A6NCT2
    • B7ZW45
    • B7ZW49
    • B9EJF2
    • Q9H1T4
    • Q9H1T5

    Protein attributes for CCDC169 Gene

    Size:
    214 amino acids
    Molecular mass:
    25253 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC169 Gene

neXtProt entry for CCDC169 Gene

Post-translational modifications for CCDC169 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC169 Gene

Domains & Families for CCDC169 Gene

Protein Domains for CCDC169 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC169 Gene

Graphical View of Domain Structure for InterPro Entry

A6NNP5

UniProtKB/Swiss-Prot:

CC169_HUMAN :
  • Belongs to the CCDC169 family.
Family:
  • Belongs to the CCDC169 family.
genes like me logo Genes that share domains with CCDC169: view

No data available for Gene Families for CCDC169 Gene

Function for CCDC169 Gene

Phenotypes for CCDC169 Gene

GenomeRNAi human phenotypes for CCDC169:
genes like me logo Genes that share phenotypes with CCDC169: view

Animal Model Products

CRISPR Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC169 Gene

Localization for CCDC169 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC169 gene
Compartment Confidence
nucleus 3
cytosol 3
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC169 Gene

Pathways & Interactions for CCDC169 Gene

SuperPathways for CCDC169 Gene

No Data Available

Interacting Proteins for CCDC169 Gene

Gene Ontology (GO) - Biological Process for CCDC169 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC169 Gene

Transcripts for CCDC169 Gene

mRNA/cDNA for CCDC169 Gene

(7) REFSEQ mRNAs :
(13) Additional mRNA sequences :
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC169 Gene

Coiled-coil domain containing 169:
Representative Sequences:

CRISPR Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC169 Gene

No ASD Table

Relevant External Links for CCDC169 Gene

GeneLoc Exon Structure for
CCDC169
ECgene alternative splicing isoforms for
CCDC169

Expression for CCDC169 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC169 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC169 Gene

This gene is overexpressed in Testis (x24.7).

Protein differential expression in normal tissues from HIPED for CCDC169 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC169 Gene



Protein tissue co-expression partners for CCDC169 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CCDC169 Gene:

CCDC169

SOURCE GeneReport for Unigene cluster for CCDC169 Gene:

Hs.656745
genes like me logo Genes that share expression patterns with CCDC169: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC169 Gene

Orthologs for CCDC169 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC169 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia CCDC169 34 35
  • 84.11 (n)
mouse
(Mus musculus)
Mammalia Ccdc169 34 16 35
  • 77.26 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc169 34
  • 76.32 (n)
cow
(Bos Taurus)
Mammalia CCDC169 35
  • 57 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC169 35
  • 45 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC169 34
  • 62.12 (n)
lizard
(Anolis carolinensis)
Reptilia CCDC169 35
  • 50 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc169 34
  • 61.58 (n)
zebrafish
(Danio rerio)
Actinopterygii ccdc169 34 35
  • 52.02 (n)
Species where no ortholog for CCDC169 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC169 Gene

ENSEMBL:
Gene Tree for CCDC169 (if available)
TreeFam:
Gene Tree for CCDC169 (if available)

Paralogs for CCDC169 Gene

(1) SIMAP similar genes for CCDC169 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC169: view

No data available for Paralogs for CCDC169 Gene

Variants for CCDC169 Gene

Sequence variations from dbSNP and Humsavar for CCDC169 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000034709 -- 36,256,715(+) CCACC(A/G)GCCTG intron-variant
rs1000039585 -- 36,298,659(+) CTTCC(A/C)GGTCA upstream-variant-2KB
rs1000066311 -- 36,294,868(+) ATCTA(C/T)AGATA intron-variant
rs1000078128 -- 36,244,225(+) AAACA(G/T)TTCCC intron-variant
rs1000116850 -- 36,294,639(+) TTATT(A/C/T)GGCCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC169 Gene

Variant ID Type Subtype PubMed ID
dgv101e215 CNV deletion 23714750
dgv949n106 CNV deletion 24896259
esv1749604 CNV deletion 17803354
esv2095309 CNV deletion 18987734
esv2666917 CNV deletion 23128226
esv2671981 CNV deletion 23128226
esv2747263 CNV deletion 23290073
esv2747265 CNV deletion 23290073
esv2747266 CNV deletion 23290073
esv2747267 CNV deletion 23290073
esv3172209 CNV deletion 24192839
esv3550316 CNV deletion 23714750
esv3631777 CNV loss 21293372
esv3631778 CNV loss 21293372
esv3631780 CNV loss 21293372
nsv1070583 CNV deletion 25765185
nsv1138215 CNV deletion 24896259
nsv1149953 CNV deletion 26484159
nsv515635 CNV gain+loss 19592680
nsv525432 CNV loss 19592680

Variation tolerance for CCDC169 Gene

Gene Damage Index Score: 4.66; 65.82% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC169 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC169

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC169 Gene

Disorders for CCDC169 Gene

Relevant External Links for CCDC169

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC169

No disorders were found for CCDC169 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC169 Gene

Publications for CCDC169 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  5. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 64

Products for CCDC169 Gene

Sources for CCDC169 Gene

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