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Aliases for CCDC168 Gene

Aliases for CCDC168 Gene

  • Coiled-Coil Domain Containing 168 2 3
  • C13orf40 3 4
  • Chromosome 13 Open Reading Frame 40 2

External Ids for CCDC168 Gene

Previous HGNC Symbols for CCDC168 Gene

  • C13orf40

Previous GeneCards Identifiers for CCDC168 Gene

  • GC13M103384

Summaries for CCDC168 Gene

GeneCards Summary for CCDC168 Gene

CCDC168 (Coiled-Coil Domain Containing 168) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC168 Gene

Genomics for CCDC168 Gene

Genomic Location for CCDC168 Gene

102,729,367 bp from pter
102,759,072 bp from pter
29,706 bases
Minus strand

Genomic View for CCDC168 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC168 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC168 Gene

No data available for Regulatory Elements for CCDC168 Gene

Proteins for CCDC168 Gene

  • Protein details for CCDC168 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 168
    Protein Accession:
    Secondary Accessions:
    • Q8N800

    Protein attributes for CCDC168 Gene

    2452 amino acids
    Molecular mass:
    277951 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC168 Gene

Proteomics data for CCDC168 Gene at MOPED

Post-translational modifications for CCDC168 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC168 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC168 Gene

Domains & Families for CCDC168 Gene

Protein Domains for CCDC168 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC168: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC168 Gene

Function for CCDC168 Gene

Phenotypes for CCDC168 Gene

GenomeRNAi human phenotypes for CCDC168:
genes like me logo Genes that share phenotypes with CCDC168: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC168 Gene

Localization for CCDC168 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCDC168 Gene

Pathways & Interactions for CCDC168 Gene

SuperPathways for CCDC168 Gene

No Data Available

Interacting Proteins for CCDC168 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000320232 for CCDC168 Gene via STRING

Gene Ontology (GO) - Biological Process for CCDC168 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC168 Gene

Drugs & Compounds for CCDC168 Gene

No Compound Related Data Available

Transcripts for CCDC168 Gene

mRNA/cDNA for CCDC168 Gene

(3) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC168 Gene

Coiled-coil domain containing 168:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC168 Gene

No ASD Table

Relevant External Links for CCDC168 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC168 Gene

mRNA expression in normal human tissues for CCDC168 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC168 Gene

This gene is overexpressed in Testis (x48.3).

Protein differential expression in normal tissues from HIPED for CCDC168 Gene

This gene is overexpressed in Cervix (20.3), Monocytes (16.6), Rectum (7.3), and Plasma (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCDC168 Gene

SOURCE GeneReport for Unigene cluster for CCDC168 Gene Hs.368382

genes like me logo Genes that share expression patterns with CCDC168: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC168 Gene

Orthologs for CCDC168 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC168 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC100855512 35
  • 74.19 (n)
  • 55.22 (a)
CCDC168 36
  • 58 (a)
(Pan troglodytes)
Mammalia LOC452647 35
  • 99.21 (n)
  • 98.35 (a)
CCDC168 36
  • 98 (a)
(Bos Taurus)
Mammalia CCDC168 36
  • 51 (a)
(Mus musculus)
Mammalia Gm8251 36
  • 36 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC168 36
  • 16 (a)
Species with no ortholog for CCDC168:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC168 Gene

Gene Tree for CCDC168 (if available)
Gene Tree for CCDC168 (if available)

Paralogs for CCDC168 Gene Pseudogenes for CCDC168 Gene

genes like me logo Genes that share paralogs with CCDC168: view

No data available for Paralogs for CCDC168 Gene

Variants for CCDC168 Gene

Sequence variations from dbSNP and Humsavar for CCDC168 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
VAR_044210 -
VAR_044211 -
VAR_044212 -
VAR_044213 -
VAR_044214 -

Variation tolerance for CCDC168 Gene

Gene Damage Index Score: 9.82; 89.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC168 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC168 Gene

Disorders for CCDC168 Gene

Relevant External Links for CCDC168

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CCDC168: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC168 Gene

Publications for CCDC168 Gene

  1. Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity. (PMID: 22792062) van Zuylen W.J. … Servant M.J. (PLoS Pathog. 2012) 67
  2. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 67
  3. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
  4. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for CCDC168 Gene

Sources for CCDC168 Gene

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