Aliases for CCDC168 Gene
Aliases for CCDC168 Gene
External Ids for CCDC168 Gene
- HGNC: 26851
- Entrez Gene: 643677
- Ensembl: ENSG00000175820
- UniProtKB: Q8NDH2
Previous HGNC Symbols for CCDC168 Gene
- C13orf40
Previous GeneCards Identifiers for CCDC168 Gene
- GC13M103384
Summaries for CCDC168 Gene
GeneCards Summary for CCDC168 Gene
CCDC168 (Coiled-Coil Domain Containing 168) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC168 Gene
Genomics for CCDC168 Gene
Regulatory Elements for CCDC168 Gene
Enhancers for CCDC168 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH13G102591 | 1.8 | FANTOM5 Ensembl ENCODE dbSUPER | 9.9 | +166.4 | 166364 | 2.4 | HDGF ARID4B SIN3A ZNF2 YY1 GLIS2 ZNF143 ZNF207 FOS SP3 | LINC00283 CCDC168 TPP2 ERCC5 LINC00555 ENSG00000276957 |
| GH13G102844 | 1.4 | ENCODE dbSUPER | 10.7 | -87.4 | -87428 | 3.9 | HDGF PKNOX1 CREB3L1 AGO1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 | BIVM TEX30 METTL21EP CCDC168 LINC00283 ERCC5 METTL21C GC13M102871 |
| GH13G102759 | 0.3 | FANTOM5 | 46 | -0.7 | -711 | 0.1 | CCDC168 KDELC1 BIVM ERCC5 TEX30 LOC105370337 | |
| GH13G102825 | 1.1 | Ensembl ENCODE dbSUPER | 10.5 | -67.2 | -67171 | 2.0 | CTCF JUN CEBPB EP300 RAD21 RFX5 JUND SMC3 STAT3 FOS | CCDC168 LINC00283 METTL21C ENSG00000272542 METTL21EP RNY5P8 GC13P102835 |
| GH13G102706 | 1 | Ensembl ENCODE | 11.4 | +51.5 | 51457 | 1.8 | TBP ZNF146 MXI1 JUN MAX ZEB1 RFX5 FOSL1 GATA2 ZNF366 | LINC00283 CCDC168 METTL21C |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CCDC168 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CCDC168 Gene
- Chromosome:
- 13
- Start:
- 102,729,367 bp from pter
- End:
- 102,759,072 bp from pter
- Size:
- 29,706 bases
- Orientation:
- Minus strand
Genomic View for CCDC168 Gene
Genes around CCDC168 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q33.1 by Ensembl
- 13q33.1 by Entrez Gene
- 13q33.1 by HGNC
CCDC168 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCDC168 Gene
Proteins for CCDC168 Gene
-
Protein details for CCDC168 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NDH2-CC168_HUMAN
- Recommended name:
- Coiled-coil domain-containing protein 168
- Protein Accession:
- Q8NDH2
- Q8N800
Protein attributes for CCDC168 Gene
- Size:
- 2452 amino acids
- Molecular mass:
- 277951 Da
- Quaternary structure:
- No Data Available
Protein Expression for CCDC168 Gene
Post-translational modifications for CCDC168 Gene
Other Protein References for CCDC168 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CCDC168
-
Abcam antibodies for CCDC168
- Invitrogen Antibodies for CCDC168
- Search GeneTex for Antibodies for CCDC168
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CCDC168
- Origene Custom Protein Services for CCDC168
- Novus Biologicals proteins for CCDC168
- Search GeneTex for Proteins for CCDC168
Assay Products
No data available for DME Specific Peptides for CCDC168 Gene
Domains & Families for CCDC168 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC168 Gene
Function for CCDC168 Gene
Phenotypes for CCDC168 Gene
- GenomeRNAi human phenotypes for CCDC168:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC168
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC168 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC168 gene
- Search ViGene Biosciences for CCDC168
CRISPR Products
- Browse CRISPR knockouts for CCDC168
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC168
- GenScript: Design CRISPR guide RNA sequences for CCDC168
miRNA Products
- Search ViGene Biosciences for CCDC168
Inhibitory RNA Products
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC168 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CCDC168
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC168
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CCDC168
-
ViGene Biosciences adenoviral particle packaged cDNA for CCDC168 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC168 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC168 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC168 Gene
Localization for CCDC168 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC168 Gene
Pathways & Interactions for CCDC168 Gene
No Data Available
Interacting Proteins for CCDC168 Gene
| Symbol | External ID(s) | Details |
|---|---|---|
| USO1 | ||
| -- |
No data available for Pathways by source and SIGNOR curated interactions for CCDC168 Gene
Transcripts for CCDC168 Gene
mRNA/cDNA for CCDC168 Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCDC168 Gene
- Coiled-coil domain containing 168:
- Representative Sequences:
CRISPR Products
- Browse CRISPR knockouts for CCDC168
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC168
- GenScript: Design CRISPR guide RNA sequences for CCDC168
miRNA Products
- Search ViGene Biosciences for CCDC168
Inhibitory RNA Products
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC168 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CCDC168
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC168
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CCDC168 Gene
mRNA differential expression in normal tissues according to GTEx for CCDC168 Gene
This gene is overexpressed in Testis (x48.3).
This gene is overexpressed in Cervix (20.3), Monocytes (16.6), Rectum (7.3), and Plasma (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC168 Gene
NURSA nuclear receptor signaling pathways regulating expression of CCDC168 Gene:
CCDC168SOURCE GeneReport for Unigene cluster for CCDC168 Gene:
Hs.368382Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC168 Gene
Orthologs for CCDC168 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC452647 34 |
|
||
| CCDC168 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | LOC100855512 34 |
|
||
| CCDC168 35 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | CCDC168 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Gm8251 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CCDC168 35 |
|
OneToOne |
- Species where no ortholog for CCDC168 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CCDC168 Gene
No data available for Paralogs for CCDC168 Gene
Variants for CCDC168 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs796052147 | Likely benign | 102,741,045(-) | AAATC(A/G)TGAGT | reference, missense | |
| rs796052148 | Likely benign | 102,746,859(-) | ATTCA(A/G)AGACG | reference, missense | |
| rs1000141080 | -- | 102,754,196(+) | TGAGA(C/T)TCCAT | intron-variant | |
| rs1000390675 | -- | 102,748,125(+) | GCTAT(G/T)TGTTT | reference, missense | |
| rs1000420057 | -- | 102,731,500(+) | TGCTG(C/T)GTTTT | reference, synonymous-codon |
Gene Damage Index Score:
9.82;
89.57% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CCDC168 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCDC168
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC168 Gene
Disorders for CCDC168 Gene
Relevant External Links for CCDC168
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CCDC168
No disorders were found for CCDC168 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC168 Gene
Publications for CCDC168 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4 64
- Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity. (PMID: 22792062) van Zuylen W.J. … Servant M.J. (PLoS Pathog. 2012) 3 64
- Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3 64
- The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
Products for CCDC168 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CCDC168
- Origene Custom Protein Services for CCDC168
- Browse OriGene Inhibitory RNA Products For CCDC168
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for CCDC168
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CCDC168
- GenScript: Next-day shipping cDNA ORF clone for CCDC168 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CCDC168
- GenScript Custom Assay Services for CCDC168
- GenScript Custom overexpressing Cell Line Services for CCDC168
- GenScript: Design CRISPR guide RNA sequences for CCDC168
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CCDC168
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CCDC168
- Novus Biologicals proteins for CCDC168
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for CCDC168
- ViGene Biosciences adenoviral particle packaged cDNA for CCDC168 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCDC168 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCDC168 gene
- Search ViGene Biosciences for CCDC168
- Horizon Cell Lines for CCDC168
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC168
- VectorBuilder custom plasmid, inducible vectors for CCDC168
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC168
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CCDC168 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer