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Aliases for CCDC167 Gene

Aliases for CCDC167 Gene

  • Coiled-Coil Domain Containing 167 2 3 5
  • C6orf129 3 4
  • Transmembrane And Coiled-Coil Domain-Containing Protein C6orf129 3
  • Chromosome 6 Open Reading Frame 129 2
  • HSPC265 3

External Ids for CCDC167 Gene

Previous HGNC Symbols for CCDC167 Gene

  • C6orf129

Summaries for CCDC167 Gene

GeneCards Summary for CCDC167 Gene

CCDC167 (Coiled-Coil Domain Containing 167) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC167 Gene

Genomics for CCDC167 Gene

Regulatory Elements for CCDC167 Gene

Promoters for CCDC167 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC167 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC167 Gene

Chromosome:
6
Start:
37,482,920 bp from pter
End:
37,499,924 bp from pter
Size:
17,005 bases
Orientation:
Minus strand

Genomic View for CCDC167 Gene

Genes around CCDC167 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC167 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC167 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC167 Gene

Proteins for CCDC167 Gene

  • Protein details for CCDC167 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P0B6-CC167_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 167
    Protein Accession:
    Q9P0B6
    Secondary Accessions:
    • Q5T7F7
    • Q9BTQ9

    Protein attributes for CCDC167 Gene

    Size:
    97 amino acids
    Molecular mass:
    11459 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF28943.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAH03515.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for CCDC167 Gene

Proteomics data for CCDC167 Gene at MOPED

Post-translational modifications for CCDC167 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC167 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC167 Gene

Domains & Families for CCDC167 Gene

Protein Domains for CCDC167 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC167 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC167: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC167 Gene

Function for CCDC167 Gene

Phenotypes for CCDC167 Gene

GenomeRNAi human phenotypes for CCDC167:
genes like me logo Genes that share phenotypes with CCDC167: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC167 Gene

Localization for CCDC167 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC167 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC167 Gene COMPARTMENTS Subcellular localization image for CCDC167 gene
Compartment Confidence
cytosol 3
cytoskeleton 2
nucleus 2
endoplasmic reticulum 1
extracellular 1
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for CCDC167 Gene

Pathways & Interactions for CCDC167 Gene

SuperPathways for CCDC167 Gene

No Data Available

Interacting Proteins for CCDC167 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000362507%0d%0a9606.ENSP00000378426%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000362507 for CCDC167 Gene via STRING

Gene Ontology (GO) - Biological Process for CCDC167 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC167 Gene

Drugs & Compounds for CCDC167 Gene

No Compound Related Data Available

Transcripts for CCDC167 Gene

mRNA/cDNA for CCDC167 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(94) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC167 Gene

Coiled-coil domain containing 167:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC167 Gene

No ASD Table

Relevant External Links for CCDC167 Gene

GeneLoc Exon Structure for
CCDC167
ECgene alternative splicing isoforms for
CCDC167

Expression for CCDC167 Gene

mRNA expression in normal human tissues for CCDC167 Gene

Protein differential expression in normal tissues from HIPED for CCDC167 Gene

This gene is overexpressed in Bone (45.7) and Breast (18.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CCDC167 Gene



SOURCE GeneReport for Unigene cluster for CCDC167 Gene Hs.284207

genes like me logo Genes that share expression patterns with CCDC167: view

Protein tissue co-expression partners for CCDC167 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC167 Gene

Orthologs for CCDC167 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC167 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CCDC167 35
  • 88.32 (n)
  • 86.6 (a)
-- 36
  • 83 (a)
OneToMany
CCDC167 36
  • 87 (a)
OneToMany
dog
(Canis familiaris)
Mammalia CCDC167 35
  • 87.97 (n)
  • 84.54 (a)
CCDC167 36
  • 48 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc167 35
  • 81.79 (n)
  • 78.35 (a)
Ccdc167 16
Ccdc167 36
  • 73 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CCDC167 35
  • 99.66 (n)
  • 98.97 (a)
CCDC167 36
  • 47 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc167 35
  • 83.16 (n)
  • 84.54 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC167 36
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC167 35
  • 65.25 (n)
  • 59.57 (a)
CCDC167 36
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC167 36
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc167 35
  • 65.98 (n)
  • 57.73 (a)
zebrafish
(Danio rerio)
Actinopterygii CCDC167 36
  • 38 (a)
OneToOne
Species with no ortholog for CCDC167:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC167 Gene

ENSEMBL:
Gene Tree for CCDC167 (if available)
TreeFam:
Gene Tree for CCDC167 (if available)

Paralogs for CCDC167 Gene

No data available for Paralogs for CCDC167 Gene

Variants for CCDC167 Gene

Sequence variations from dbSNP and Humsavar for CCDC167 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs914354 -- 37,490,898(+) AGCAG(C/T)CCCCA intron-variant
rs756202 -- 37,492,574(-) TTTCC(G/T)TCTCC intron-variant
rs879482 -- 37,489,887(+) GTGAC(C/G)GGCAA intron-variant
rs931648 -- 37,498,043(+) TTTTT(C/T)CCCAC intron-variant
rs931649 -- 37,498,303(+) gccac(C/T)gagtt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC167 Gene

Variant ID Type Subtype PubMed ID
esv2752124 CNV Gain 17911159

Variation tolerance for CCDC167 Gene

Residual Variation Intolerance Score: 47.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.48; 10.44% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC167 Gene

HapMap Linkage Disequilibrium report
CCDC167

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC167 Gene

Disorders for CCDC167 Gene

Relevant External Links for CCDC167

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC167

No disorders were found for CCDC167 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC167 Gene

Publications for CCDC167 Gene

  1. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3 67
  2. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PMID: 21103663) Schaafhausen A. … MA1ller C.R. (Thromb. Haemost. 2011) 3
  3. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PMID: 19204726) Chapuis J. … Lambert J.C. (Mol. Psychiatry 2009) 3
  4. A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (PMID: 19734545) Need A.C. … Goldstein D.B. (Hum. Mol. Genet. 2009) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for CCDC167 Gene

Sources for CCDC167 Gene

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