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Aliases for CCDC166 Gene

Aliases for CCDC166 Gene

  • Coiled-Coil Domain Containing 166 2 3 5

External Ids for CCDC166 Gene

Previous GeneCards Identifiers for CCDC166 Gene

  • GC08M144789

Summaries for CCDC166 Gene

GeneCards Summary for CCDC166 Gene

CCDC166 (Coiled-Coil Domain Containing 166) is a Protein Coding gene.

Additional gene information for CCDC166 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC166 Gene

Genomics for CCDC166 Gene

Genomic Locations for CCDC166 Gene

Genomic Locations for CCDC166 Gene
1,416 bases
Minus strand

Genomic View for CCDC166 Gene

Genes around CCDC166 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC166 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC166 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC166 Gene

No data available for Regulatory Elements for CCDC166 Gene

Proteins for CCDC166 Gene

  • Protein details for CCDC166 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 166
    Protein Accession:

    Protein attributes for CCDC166 Gene

    439 amino acids
    Molecular mass:
    48709 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC166 Gene

Post-translational modifications for CCDC166 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC166 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC166 Gene

Domains & Families for CCDC166 Gene

Gene Families for CCDC166 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC166 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC166: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CCDC166 Gene

Function for CCDC166 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC166 Gene

Localization for CCDC166 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CCDC166 Gene

Pathways & Interactions for CCDC166 Gene

SuperPathways for CCDC166 Gene

No Data Available

Interacting Proteins for CCDC166 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
Selected Interacting proteins: ENSP00000437468 for CCDC166 Gene via STRING

Gene Ontology (GO) - Biological Process for CCDC166 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC166 Gene

Drugs & Compounds for CCDC166 Gene

No Compound Related Data Available

Transcripts for CCDC166 Gene

mRNA/cDNA for CCDC166 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC166 Gene

Coiled-coil domain containing 166:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC166 Gene

No ASD Table

Relevant External Links for CCDC166 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC166 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC166 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC166 Gene

This gene is overexpressed in Testis (x39.9).

Protein differential expression in normal tissues from HIPED for CCDC166 Gene

This gene is overexpressed in Nasal epithelium (66.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC166 Gene

Protein tissue co-expression partners for CCDC166 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC166 Gene:


SOURCE GeneReport for Unigene cluster for CCDC166 Gene:

genes like me logo Genes that share expression patterns with CCDC166: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC166 Gene

Orthologs for CCDC166 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC166 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CCDC166 33
  • 99.12 (n)
(Canis familiaris)
Mammalia CCDC166 33
  • 79.44 (n)
(Bos Taurus)
Mammalia CCDC166 33 34
  • 76.37 (n)
(Mus musculus)
Mammalia Ccdc166 33 16 34
  • 71.16 (n)
(Rattus norvegicus)
Mammalia Ccdc166 33
  • 70.28 (n)
(Monodelphis domestica)
Mammalia CCDC166 34
  • 52 (a)
(Gallus gallus)
Aves LOC100859066 33
  • 53.22 (n)
(Anolis carolinensis)
Reptilia CCDC166 34
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731877 33
  • 55.96 (n)
(Danio rerio)
Actinopterygii LOC100538228 33
  • 42.88 (n)
Species where no ortholog for CCDC166 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC166 Gene

Gene Tree for CCDC166 (if available)
Gene Tree for CCDC166 (if available)

Paralogs for CCDC166 Gene

No data available for Paralogs for CCDC166 Gene

Variants for CCDC166 Gene

Sequence variations from dbSNP and Humsavar for CCDC166 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001540393 -- 143,708,054(+) CGGCC(C/G)CCGCA nc-transcript-variant, reference, missense
rs1001874220 -- 143,706,515(+) GCTCT(C/T)TTGCA downstream-variant-500B, upstream-variant-2KB
rs1002540127 -- 143,709,168(+) ACAGA(A/C)CCTGT intron-variant, upstream-variant-2KB
rs1003158765 -- 143,708,875(+) ACCCG(A/C)TCAGC intron-variant, upstream-variant-2KB
rs1005566324 -- 143,706,851(+) CCCTC(A/G)GTGAG upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for CCDC166 Gene

Variant ID Type Subtype PubMed ID
nsv612893 CNV loss 21841781
nsv519816 CNV loss 19592680
nsv466007 CNV loss 19166990

Variation tolerance for CCDC166 Gene

Gene Damage Index Score: 5.38; 71.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC166 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC166 Gene

Disorders for CCDC166 Gene

Relevant External Links for CCDC166

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC166 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC166 Gene

Publications for CCDC166 Gene

  1. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 4 60

Products for CCDC166 Gene

Sources for CCDC166 Gene

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