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Aliases for CCDC159 Gene

Aliases for CCDC159 Gene

  • Coiled-Coil Domain Containing 159 2 3 5

External Ids for CCDC159 Gene

Previous GeneCards Identifiers for CCDC159 Gene

  • GC19P011321
  • GC19P011455
  • GC19P011033

Summaries for CCDC159 Gene

GeneCards Summary for CCDC159 Gene

CCDC159 (Coiled-Coil Domain Containing 159) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC159 Gene

Genomics for CCDC159 Gene

Regulatory Elements for CCDC159 Gene

Enhancers for CCDC159 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC159 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC159 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC159 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC159 Gene

11,344,684 bp from pter
11,354,944 bp from pter
10,261 bases
Plus strand

Genomic View for CCDC159 Gene

Genes around CCDC159 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC159 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC159 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC159 Gene

Proteins for CCDC159 Gene

  • Protein details for CCDC159 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 159
    Protein Accession:
    Secondary Accessions:
    • B4DEG3
    • B4DWR8
    • B4E133
    • B7ZAM4

    Protein attributes for CCDC159 Gene

    412 amino acids
    Molecular mass:
    46012 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAG63130.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=BC038439; Type=Frameshift; Positions=55; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC159 Gene


neXtProt entry for CCDC159 Gene

Proteomics data for CCDC159 Gene at MOPED

Post-translational modifications for CCDC159 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC159 Gene

Domains & Families for CCDC159 Gene

Protein Domains for CCDC159 Gene


Suggested Antigen Peptide Sequences for CCDC159 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC159: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC159 Gene

Function for CCDC159 Gene

Phenotypes for CCDC159 Gene

genes like me logo Genes that share phenotypes with CCDC159: view

Animal Models for CCDC159 Gene

MGI Knock Outs for CCDC159:

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC159 Gene

Localization for CCDC159 Gene

Subcellular locations from

Jensen Localization Image for CCDC159 Gene COMPARTMENTS Subcellular localization image for CCDC159 gene
Compartment Confidence
nucleus 4
cytosol 3
extracellular 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC159 Gene

Pathways & Interactions for CCDC159 Gene

SuperPathways for CCDC159 Gene

No Data Available

Interacting Proteins for CCDC159 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000402239 for CCDC159 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CCDC159 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC159 Gene

Drugs & Compounds for CCDC159 Gene

No Compound Related Data Available

Transcripts for CCDC159 Gene

Unigene Clusters for CCDC159 Gene

Coiled-coil domain containing 159:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC159 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12
SP1: - -
SP2: - - -
SP3: - -
SP4: - - - -
SP5: -
SP6: - - - - - - -
SP7: -
SP8: - -

Relevant External Links for CCDC159 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC159 Gene

mRNA expression in normal human tissues for CCDC159 Gene

SOURCE GeneReport for Unigene cluster for CCDC159 Gene Hs.631636

genes like me logo Genes that share expression patterns with CCDC159: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC159 Gene

Orthologs for CCDC159 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC159 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC159 35
  • 83.56 (n)
  • 78.28 (a)
CCDC159 36
  • 56 (a)
(Canis familiaris)
Mammalia CCDC159 35
  • 86.89 (n)
  • 84.07 (a)
CCDC159 36
  • 79 (a)
(Mus musculus)
Mammalia Ccdc159 35
  • 81.48 (n)
  • 79.21 (a)
Ccdc159 16
Ccdc159 36
  • 54 (a)
(Pan troglodytes)
Mammalia CCDC159 35
  • 99.1 (n)
  • 98.32 (a)
CCDC159 36
  • 69 (a)
(Rattus norvegicus)
Mammalia Ccdc159 35
  • 80.68 (n)
  • 78.09 (a)
(Monodelphis domestica)
Mammalia CCDC159 36
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC159 36
  • 39 (a)
(Anolis carolinensis)
Reptilia CCDC159 36
  • 40 (a)
Species with no ortholog for CCDC159:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC159 Gene

Gene Tree for CCDC159 (if available)
Gene Tree for CCDC159 (if available)

Paralogs for CCDC159 Gene

No data available for Paralogs for CCDC159 Gene

Variants for CCDC159 Gene

Sequence variations from dbSNP and Humsavar for CCDC159 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
VAR_043032 -
rs12976608 -- 11,348,584(+) ATTGC(C/T)GGCCG intron-variant
rs12984429 -- 11,349,317(+) CTTCA(G/T)CACCT intron-variant
rs62131132 -- 11,352,268(+) GGGCA(A/G)GTCAC intron-variant, reference, synonymous-codon
rs1129743 -- 11,350,175(+) TGCAG(A/C)AAATC nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for CCDC159 Gene

Variant ID Type Subtype PubMed ID
nsv833752 CNV Loss 17160897
nsv519802 CNV Loss 19592680

Variation tolerance for CCDC159 Gene

Residual Variation Intolerance Score: 70.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.77; 78.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC159 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC159 Gene

Disorders for CCDC159 Gene

Relevant External Links for CCDC159

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC159 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC159 Gene

Publications for CCDC159 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 67
  2. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for CCDC159 Gene

Sources for CCDC159 Gene