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Aliases for CCDC158 Gene

Aliases for CCDC158 Gene

  • Coiled-Coil Domain Containing 158 2 3

External Ids for CCDC158 Gene

Previous GeneCards Identifiers for CCDC158 Gene

  • GC04M077454
  • GC04M077234
  • GC04M072986

Summaries for CCDC158 Gene

GeneCards Summary for CCDC158 Gene

CCDC158 (Coiled-Coil Domain Containing 158) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC158 Gene

Genomics for CCDC158 Gene

Regulatory Elements for CCDC158 Gene

Genomic Location for CCDC158 Gene

76,312,997 bp from pter
76,421,893 bp from pter
108,897 bases
Minus strand

Genomic View for CCDC158 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC158 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC158 Gene

Proteins for CCDC158 Gene

  • Protein details for CCDC158 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 158
    Protein Accession:
    Secondary Accessions:
    • Q8IYQ1
    • Q8N7D4
    • Q8N7E3

    Protein attributes for CCDC158 Gene

    1113 amino acids
    Molecular mass:
    127140 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05347.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC05359.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BC035224; Type=Frameshift; Positions=204; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC158 Gene


neXtProt entry for CCDC158 Gene

Proteomics data for CCDC158 Gene at MOPED

Post-translational modifications for CCDC158 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC158 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC158 Gene

Domains & Families for CCDC158 Gene

Protein Domains for CCDC158 Gene


Suggested Antigen Peptide Sequences for CCDC158 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC158: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC158 Gene

Function for CCDC158 Gene

Phenotypes for CCDC158 Gene

GenomeRNAi human phenotypes for CCDC158:
genes like me logo Genes that share phenotypes with CCDC158: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC158 Gene

Localization for CCDC158 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCDC158 Gene

Pathways & Interactions for CCDC158 Gene

SuperPathways for CCDC158 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC158 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC158 Gene

Drugs & Compounds for CCDC158 Gene

No Compound Related Data Available

Transcripts for CCDC158 Gene

Unigene Clusters for CCDC158 Gene

Coiled-coil domain containing 158:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC158 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^
SP1: -
SP2: - - - - - - - - - - - -

ExUns: 22 ^ 23 ^ 24 ^ 25

Relevant External Links for CCDC158 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC158 Gene

mRNA expression in normal human tissues for CCDC158 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC158 Gene

This gene is overexpressed in Testis (x30.8).

Protein differential expression in normal tissues from HIPED for CCDC158 Gene

This gene is overexpressed in Cervix (27.0), Lymph node (17.7), and Amniocyte (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCDC158 Gene

SOURCE GeneReport for Unigene cluster for CCDC158 Gene Hs.529680

genes like me logo Genes that share expression patterns with CCDC158: view

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC158 Gene

Orthologs for CCDC158 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC158 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC158 35
  • 90.5 (n)
  • 91.37 (a)
CCDC158 36
  • 91 (a)
(Canis familiaris)
Mammalia CCDC158 35
  • 91.19 (n)
  • 93.08 (a)
CCDC158 36
  • 93 (a)
(Mus musculus)
Mammalia Ccdc158 35
  • 85.95 (n)
  • 91.88 (a)
Ccdc158 16
Ccdc158 36
  • 92 (a)
(Pan troglodytes)
Mammalia CCDC158 35
  • 99.55 (n)
  • 99.64 (a)
CCDC158 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Ccdc158 35
  • 85.81 (n)
  • 91.9 (a)
(Monodelphis domestica)
Mammalia CCDC158 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC158 36
  • 52 (a)
(Anolis carolinensis)
Reptilia CCDC158 36
  • 47 (a)
Species with no ortholog for CCDC158:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC158 Gene

Gene Tree for CCDC158 (if available)
Gene Tree for CCDC158 (if available)

Paralogs for CCDC158 Gene

No data available for Paralogs for CCDC158 Gene

Variants for CCDC158 Gene

Sequence variations from dbSNP and Humsavar for CCDC158 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
VAR_039909 -
VAR_039910 -

Structural Variations from Database of Genomic Variants (DGV) for CCDC158 Gene

Variant ID Type Subtype PubMed ID
nsv7363 OTHER Inversion 18451855
dgv1647e1 CNV Complex 17122850
nsv441891 CNV CNV 18776908
nsv10526 CNV Gain 18304495

Variation tolerance for CCDC158 Gene

Residual Variation Intolerance Score: 83.57% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.08; 75.34% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC158 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC158 Gene

Disorders for CCDC158 Gene

Relevant External Links for CCDC158

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CCDC158: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC158 Gene

Publications for CCDC158 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 67
  5. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 Complexes in mammalian cells. (PMID: 21282530) Vandamme J. … Angrand P.O. (Mol. Cell. Proteomics 2011) 67

Products for CCDC158 Gene

Sources for CCDC158 Gene

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