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CCDC155 Gene

protein-coding   GIFtS: 42
GCID: GC19P049891

Coiled-Coil Domain Containing 155

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Coiled-Coil Domain Containing 1551 2
KASH52 3
KASH Domain-Containing Protein 52 3
Protein KASH52
Coiled-Coil Domain-Containing Protein 1553

External Ids:    HGNC: 265201   Entrez Gene: 1478722   Ensembl: ENSG000001616097   UniProtKB: Q8N6L03   

Export aliases for CCDC155 gene to outside databases

Previous GC identifers: GC19P054584 GC19P046269


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CCDC155 Gene:
CCDC155 (coiled-coil domain containing 155) is a protein-coding gene. GO annotations related to this gene include calcium ion binding.

UniProtKB/Swiss-Prot: KASH5_HUMAN, Q8N6L0
Function: May be involved in meiotic chromosome dynamics and homolog pairing (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC155 gene promoter:
         TBP   Pax-5   Egr-1   MyoD   AP-2gamma   Egr-4   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for CCDC155

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC155


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.33   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.33

CCDC155 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC155 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P049891:  view genomic region     (about GC identifiers)

Start:
49,891,475 bp from pter      End:
49,921,256 bp from pter
Size:
29,782 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KASH5_HUMAN, Q8N6L0 (See protein sequence)
Recommended Name: Protein KASH5  
Size: 562 amino acids; 62783 Da
Subunit: Interacts (via the last 22 AA) with SUN1; this interaction mediates telomere localization (By
similarity). Interacts with dynein-dynactin motor complex (By similarity)
Secondary accessions: Q96MC3

Explore the universe of human proteins at neXtProt for CCDC155: NX_Q8N6L0

Explore proteomics data for CCDC155 at MOPED


See CCDC155 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_653289.3  
ENSEMBL proteins: 
 ENSP00000404220   ENSP00000469367   ENSP00000470765   ENSP00000468838   ENSP00000471777  
 ENSP00000469435   ENSP00000470819  

CCDC155 Human Recombinant Protein Products:

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Novus Biologicals CCDC155 Protein
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Cloud-Clone Corp. Proteins for CCDC155

 
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antibodies-online proteins for CCDC155 (4 products) 

 
antibodies-online peptides for CCDC155

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LSBio Antibodies in human, mouse, rat for CCDC155
antibodies-online antibodies for CCDC155 (5 products) 

CCDC155 Assay Products:

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Cloud-Clone Corp. ELISAs for CCDC155
Cloud-Clone Corp. CLIAs for CCDC155
Search eBioscience for ELISAs for CCDC155 
antibodies-online kits for CCDC155 (18 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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4 InterPro protein domains:
 IPR011992 EF-hand-dom_pair
 IPR024950 DUSP
 IPR028170 KASH5
 IPR028168 KASH5_coiled-coil

Graphical View of Domain Structure for InterPro Entry Q8N6L0

ProtoNet protein and cluster: Q8N6L0

UniProtKB/Swiss-Prot: KASH5_HUMAN, Q8N6L0
Domain: The C-terminal 22 AA is required and sufficient for localization to telomeres at the nuclear envelope (By
similarity)


Find genes that share domains with CCDC155           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: KASH5_HUMAN, Q8N6L0
Function: May be involved in meiotic chromosome dynamics and homolog pairing (By similarity)

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005509calcium ion binding IEA--
GO:0005515protein binding ----
     
Find genes that share ontologies with CCDC155           About GenesLikeMe


Phenotypes:
     2 GenomeRNAi human phenotypes for CCDC155:
 Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC155
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC155
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC155

miRNA
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Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat CCDC155

Gene Editing
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GenScript: all cDNA clones in your preferred vector: CCDC155 (NM_144688)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC155

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC155


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
KASH5_HUMAN, Q8N6L0: Nucleus outer membrane; Single-pass type IV membrane protein; Cytoplasmic side (Potential).
Nucleus. Chromosome, telomere (By similarity). Note=Localized exclusively at telomeres from the leptotene to
diplotene stages (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
golgi apparatus4
cytosol2
mitochondrion1
peroxisome1
plasma membrane1

Gene Ontology (GO): 5 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000781chromosome, telomeric region ISS--
GO:0005640nuclear outer membrane IEA--
GO:0005794Golgi apparatus ----
GO:0016021integral component of membrane IEA--
GO:0043231intracellular membrane-bounded organelle ----

Find genes that share ontologies with CCDC155           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC155
Interactions:

    Search GeneGlobe Interaction Network for CCDC155

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for CCDC155 (Q8N6L02, 3 ENSP000004042204) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CCDC87Q9NVE42, 3, ENSP000003284874MINT-67475 I2D: score=4 STRING: ENSP00000328487
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CCDC155 (KASH5)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for CCDC155 gene: 
NM_144688.4  

Unigene Cluster for CCDC155:

Coiled-coil domain containing 155
Hs.662085  [show with all ESTs]
Unigene Representative Sequence: NM_144688
15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000447857(uc002pnl.2 uc002pnm.2 uc010emx.2) ENST00000600895
ENST00000598730 ENST00000596771 ENST00000596862 ENST00000597993 ENST00000593725
ENST00000594905 ENST00000595828 ENST00000594043 ENST00000600570 ENST00000596130
ENST00000593631 ENST00000593362 ENST00000596419
miRNA
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Search for qRT-PCR Assays for microRNAs that regulate CCDC155
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CCDC155
Predesigned siRNA for gene silencing in human, mouse, rat CCDC155
Clone
Products:
     
OriGene clones in human, mouse for CCDC155 (see all 6)
OriGene ORF clones in mouse, rat for CCDC155
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CCDC155 (NM_144688)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC155
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC155
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for CCDC155
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC155
  QuantiTect SYBR Green Assays in human, mouse, rat CCDC155
  QuantiFast Probe-based Assays in human, mouse, rat CCDC155

Additional mRNA sequence: 

AK057220.1 AK097696.1 BC029811.1 

8 DOTS entries:

DT.405876  DT.99927574  DT.99930009  DT.100748133  DT.121457231  DT.100660540  DT.121457232  DT.121457246 

5 AceView cDNA sequences:

AK057220 AK097696 BC029811 AK128169 NM_144688 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for CCDC155 (see all 7)    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a ·
SP1:              -           -           -     -                       -                             -                                                         
SP2:                          -           -     -                       -                                                                                       
SP3:                                                                                                                                                            
SP4:              -           -                                                                                                                                 
SP5:                                                        -           -                                                                                       

ExUns: 19b ^ 20 ^ 21 ^ 22
SP1:  -                     
SP2:                        
SP3:                        
SP4:                        
SP5:                        


ECgene alternative splicing isoforms for CCDC155

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CCDC155 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CTCAGGAGTT
CCDC155 Expression
About this image


CCDC155 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Brain (Nervous System)    fully expand to see all 3 entries
         Cerebral Cortex
 
 Testis (Reproductive System)
         Leydig Cells Testis Interstitium
 
 Trophoblast (Extraembryonic Tissues)
         Trophoblast Cells Trophoblast
 
 Pancreas (Endocrine System)
         Islets of Langerhans
 
 Liver (Hepatobiliary System)
         Hepatocytes Liver Lobule
CCDC155 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CCDC155 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.662085
    Custom PCR Arrays for CCDC155
Primer
Products:
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QuantiFast Probe-based Assays in human, mouse, rat CCDC155
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC155

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CCDC155 gene from Selected species (see all 7)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Ccdc1551 , 5 coiled-coil domain containing 1551, 5 77.72(n)1
73.3(a)1
  7 (29.17 cM)5
3846191  NM_201374.21  NP_958762.21 
 451836245 
lizard
(Anolis carolinensis)
Reptilia CCDC1556
coiled-coil domain containing 155
42(a)
1 ↔ 1
GL343355.1(145683-152279)


ENSEMBL Gene Tree for CCDC155 (if available)
TreeFam Gene Tree for CCDC155 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CCDC155 (see all 782)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs677412411,2
C--49889784(+) AAAAC-/AAAAAA 1 -- us2k11Minor allele frequency- A:0.00CSA 2
rs1425686981,2
C--49889799(+) ACAGC-/AAGATC 1 -- us2k10--------
rs1917583171,2
--49890002(+) TGGACA/GCGGAG 1 -- us2k10--------
rs1835330531,2
--49890039(+) GGAGGA/GGAAGG 1 -- us2k10--------
rs1865732881,2
--49890155(+) GGAAGA/GGAGGG 1 -- us2k10--------
rs1914064281,2
--49890223(+) GAGGAC/GAGGAG 1 -- us2k10--------
rs1856428221,2
--49890233(+) GCAGAA/GGGGAA 1 -- us2k10--------
rs104039581,2
C--49890245(+) ggaggC/Ggggag 1 -- us2k10--------
rs1167046641,2
F--49890306(+) GGGGAG/AGAGAG 1 -- us2k11Minor allele frequency- A:0.14WA 118
rs735765181,2
C--49890312(+) GAGAGA/GAGCAG 1 -- us2k10--------

HapMap Linkage Disequilibrium report for CCDC155 (49891475 - 49921256 bp)

Structural Variations
     Database of Genomic Variants (DGV) 8 variations for CCDC155:    About this table    
Variant IDTypeSubtypePubMed ID
esv2718713CNV Deletion23290073
esv2718714CNV Deletion23290073
nsv138000CNV Insertion16902084
dgv52n68CNV Loss17160897
nsv912262CNV Loss21882294
nsv912261CNV Loss21882294
nsv912263CNV Loss21882294
nsv9739CNV Gain+Loss18304495

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CCDC155
DNA2.0 Custom Variant and Variant Library Synthesis for CCDC155

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CCDC155 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with CCDC155)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  2. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
  3. A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis. (PubMed id 22826121)1 Morimoto A....Watanabe Y. (J. Cell Biol. 2012)
  4. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
  5. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PubMed id 16751776)1 Girard A....Carmell M.A. (Nature 2006)
  6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  7. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
  8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  9. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 147872 HGNC: 26520 AceView: FLJ32658 Ensembl:ENSG00000161609 euGenes: HUgn147872
ECgene: CCDC155 H-InvDB: CCDC155

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CCDC155 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CCDC155 gene:
Search GeneIP for patents involving CCDC155

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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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