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Aliases for CCDC155 Gene

Aliases for CCDC155 Gene

  • Coiled-Coil Domain Containing 155 2 3
  • KASH Domain-Containing Protein 5 3 4
  • KASH5 3 4
  • Coiled-Coil Domain-Containing Protein 155 4
  • Protein KASH5 3

External Ids for CCDC155 Gene

Previous GeneCards Identifiers for CCDC155 Gene

  • GC19P054584
  • GC19P049891
  • GC19P046269

Summaries for CCDC155 Gene

GeneCards Summary for CCDC155 Gene

CCDC155 (Coiled-Coil Domain Containing 155) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding.

UniProtKB/Swiss-Prot for CCDC155 Gene

  • May be involved in meiotic chromosome dynamics and homolog pairing.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC155 Gene

Genomics for CCDC155 Gene

Regulatory Elements for CCDC155 Gene

Genomic Location for CCDC155 Gene

49,388,218 bp from pter
49,417,999 bp from pter
29,782 bases
Plus strand

Genomic View for CCDC155 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC155 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC155 Gene

Proteins for CCDC155 Gene

  • Protein details for CCDC155 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein KASH5
    Protein Accession:
    Secondary Accessions:
    • Q96MC3

    Protein attributes for CCDC155 Gene

    562 amino acids
    Molecular mass:
    62783 Da
    Quaternary structure:
    • Interacts (via the last 22 AA) with SUN1; this interaction mediates telomere localization. Interacts with dynein-dynactin motor complex.

neXtProt entry for CCDC155 Gene

Proteomics data for CCDC155 Gene at MOPED

Post-translational modifications for CCDC155 Gene

No Post-translational modifications

Other Protein References for CCDC155 Gene

No data available for DME Specific Peptides for CCDC155 Gene

Domains for CCDC155 Gene

Protein Domains for CCDC155 Gene

Suggested Antigen Peptide Sequences for CCDC155 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8N6L0
  • The C-terminal 22 AA is required and sufficient for localization to telomeres at the nuclear envelope.
genes like me logo Genes that share domains with CCDC155: view

No data available for Gene Families for CCDC155 Gene

Function for CCDC155 Gene

Molecular function for CCDC155 Gene

UniProtKB/Swiss-Prot Function: May be involved in meiotic chromosome dynamics and homolog pairing.

Gene Ontology (GO) - Molecular Function for CCDC155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding --
GO:0005515 protein binding IPI 25416956
GO:0042802 identical protein binding IEA --
GO:0070840 dynein complex binding IEA --
genes like me logo Genes that share ontologies with CCDC155: view
genes like me logo Genes that share phenotypes with CCDC155: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC155 Gene

Localization for CCDC155 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC155 Gene

Nucleus outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Nucleus. Chromosome, telomere. Note=Localized exclusively at telomeres from the leptotene to diplotene stages. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for CCDC155 Gene COMPARTMENTS Subcellular localization image for CCDC155 gene
Compartment Confidence
nucleus 5
golgi apparatus 4
cytosol 2
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for CCDC155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000781 chromosome, telomeric region ISS --
GO:0000800 lateral element IEA --
GO:0005634 nucleus --
GO:0005640 nuclear outer membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CCDC155: view

Pathways for CCDC155 Gene

SuperPathways for CCDC155 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000724 double-strand break repair via homologous recombination IEA --
GO:0007129 synapsis IEA --
GO:0007283 spermatogenesis IEA --
GO:0048477 oogenesis IEA --
GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation IEA --
genes like me logo Genes that share ontologies with CCDC155: view

No data available for Pathways by source for CCDC155 Gene

Transcripts for CCDC155 Gene

mRNA/cDNA for CCDC155 Gene

(5) Selected AceView cDNA sequences:
(12) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(15) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC155 Gene

Coiled-coil domain containing 155:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC155 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a ·
SP1: - - - - - -
SP2: - - - -
SP4: - -
SP5: - -

ExUns: 19b ^ 20 ^ 21 ^ 22
SP1: -

Relevant External Links for CCDC155 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC155 Gene

mRNA expression in normal human tissues for CCDC155 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC155 Gene

This gene is overexpressed in Testis (36.5), Brain - Cerebellum (7.9), and Brain - Cerebellar Hemisphere (6.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC155 Gene

SOURCE GeneReport for Unigene cluster for CCDC155 Gene Hs.662085

genes like me logo Genes that share expressions with CCDC155: view

No data available for mRNA Expression by UniProt/SwissProt for CCDC155 Gene

Orthologs for CCDC155 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC155 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CCDC155 35
  • 97.03 (n)
  • 95.89 (a)
CCDC155 36
  • 99 (a)
(Bos Taurus)
Mammalia CCDC155 35
  • 85.16 (n)
  • 80.23 (a)
CCDC155 36
  • 80 (a)
(Canis familiaris)
Mammalia CCDC155 35
  • 84.7 (n)
  • 80.25 (a)
CCDC155 36
  • 79 (a)
(Mus musculus)
Mammalia Ccdc155 35
  • 77.72 (n)
  • 73.3 (a)
Ccdc155 16
Ccdc155 36
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC155 36
  • 47 (a)
(Rattus norvegicus)
Mammalia Ccdc155 35
  • 77.88 (n)
  • 73.52 (a)
(Anolis carolinensis)
Reptilia CCDC155 36
  • 42 (a)
Species with no ortholog for CCDC155:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC155 Gene

Gene Tree for CCDC155 (if available)
Gene Tree for CCDC155 (if available)

Paralogs for CCDC155 Gene

No data available for Paralogs for CCDC155 Gene

Variants for CCDC155 Gene

Sequence variations from dbSNP and Humsavar for CCDC155 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1320302 -- 49,415,557(-) GCAGA(A/C)TCCAG intron-variant
rs2946847 -- 49,413,782(+) TACAA(C/T)GGCTC intron-variant
rs4801797 -- 49,414,699(+) TGCCT(A/G)GCCTC intron-variant
rs4802602 -- 49,394,692(+) GGTAT(C/T)GTAAG intron-variant
rs7246233 -- 49,392,293(+) ACAAG(C/G)GACAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC155 Gene

Variant ID Type Subtype PubMed ID
nsv9739 CNV Gain+Loss 18304495
dgv52n68 CNV Loss 17160897
nsv912261 CNV Loss 21882294
esv2718713 CNV Deletion 23290073
nsv912262 CNV Loss 21882294
nsv912263 CNV Loss 21882294
esv2718714 CNV Deletion 23290073
nsv138000 CNV Insertion 16902084

Relevant External Links for CCDC155 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC155 Gene

Disorders for CCDC155 Gene

No disorders were found for CCDC155 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC155 Gene

Publications for CCDC155 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for CCDC155 Gene

Sources for CCDC155 Gene

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