Aliases for CCDC154 Gene
Aliases for CCDC154 Gene
External Ids for CCDC154 Gene
- HGNC: 34454
- Entrez Gene: 645811
- Ensembl: ENSG00000197599
- UniProtKB: A6NI56
Previous HGNC Symbols for CCDC154 Gene
- C16orf29
Previous GeneCards Identifiers for CCDC154 Gene
- GC16M001426
- GC16M001484
- GC16M001412
- GC16M001434
- GC16M001439
- GC16M001445
- GC16M001453
- GC16M001458
Summaries for CCDC154 Gene
GeneCards Summary for CCDC154 Gene
CCDC154 (Coiled-Coil Domain Containing 154) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC154 Gene
Genomics for CCDC154 Gene
Regulatory Elements for CCDC154 Gene
Enhancers for CCDC154 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CCDC154 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CCDC154 gene promoter:
Regulatory Element Products
Genomic Location for CCDC154 Gene
- Chromosome:
- 16
- Start:
- 1,433,425 bp from pter
- End:
- 1,444,844 bp from pter
- Size:
- 11,420 bases
- Orientation:
- Minus strand
Genomic View for CCDC154 Gene
Genes around CCDC154 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.3 by Ensembl
- 16p13.3 by Entrez Gene
- 16p13.3 by HGNC
CCDC154 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCDC154 Gene
Proteins for CCDC154 Gene
-
Protein details for CCDC154 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A6NI56-CC154_HUMAN
- Recommended name:
- Coiled-coil domain-containing protein 154
- Protein Accession:
- A6NI56
- G9JV18
Protein attributes for CCDC154 Gene
- Size:
- 674 amino acids
- Molecular mass:
- 76013 Da
- Quaternary structure:
- No Data Available
- Miscellaneous:
-
- Overexpression suppresses cell proliferation by inducing G2/M arrest.
Protein Expression for CCDC154 Gene
Post-translational modifications for CCDC154 Gene
Other Protein References for CCDC154 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CCDC154
- Invitrogen Antibodies for CCDC154
- Search GeneTex for Antibodies for CCDC154
Protein Products
-
OriGene Purified Proteins for CCDC154
- Search Origene for MassSpec and Protein Over-expression Lysates for CCDC154
- Origene Custom Protein Services for CCDC154
- Novus Biologicals proteins for CCDC154
- Search GeneTex for Proteins for CCDC154
Assay Products
No data available for DME Specific Peptides for CCDC154 Gene
Domains & Families for CCDC154 Gene
Protein Domains for CCDC154 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CCDC154 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC154 Gene
Function for CCDC154 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC154
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC154 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC154 gene
- Search ViGene Biosciences for CCDC154
CRISPR Products
-
OriGene CRISPR knockouts for CCDC154
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC154
- GenScript: Design CRISPR guide RNA sequences for CCDC154
miRNA Products
- Search ViGene Biosciences for CCDC154
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for CCDC154
- Browse OriGene Inhibitory RNA Products For CCDC154
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC154 gene
Clone Products
-
OriGene ORF clones in human for CCDC154
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CCDC154
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC154
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CCDC154
-
ViGene Biosciences adenoviral particle packaged cDNA for CCDC154 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC154 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC154 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC154 Gene
Localization for CCDC154 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCDC154 Gene
- Early endosome.
| Compartment | Confidence |
|---|---|
| endosome | 4 |
| nucleus | 2 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005769 | early endosome | IEA | -- |
Transcripts for CCDC154 Gene
mRNA/cDNA for CCDC154 Gene
- (1) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCDC154 Gene
- Coiled-coil domain containing 154:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for CCDC154
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC154
- GenScript: Design CRISPR guide RNA sequences for CCDC154
miRNA Products
- Search ViGene Biosciences for CCDC154
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for CCDC154
- Browse OriGene Inhibitory RNA Products For CCDC154
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC154 gene
Clone Products
-
OriGene ORF clones in human for CCDC154
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- VectorBuilder custom plasmid, inducible vectors for CCDC154
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC154
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||
| SP5: | - |
Expression for CCDC154 Gene
mRNA differential expression in normal tissues according to GTEx for CCDC154 Gene
This gene is overexpressed in Testis (x7.0) and Pituitary (x4.1).
This gene is overexpressed in Gallbladder (64.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC154 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CCDC154 Gene:
CCDC154SOURCE GeneReport for Unigene cluster for CCDC154 Gene:
Hs.355232Primer Products
-
OriGene qPCR primer pairs for CCDC154
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC154 Gene
Orthologs for CCDC154 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCDC154 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CCDC154 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CCDC154 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccdc154 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ccdc154 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCDC154 35 |
|
OneToOne |
- Species where no ortholog for CCDC154 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CCDC154 Gene
No data available for Paralogs for CCDC154 Gene
Variants for CCDC154 Gene
| SNP ID | Clin | Chr 16 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10903009 | Likely benign | 1,446,004(+) | GGGCC(C/T)GTGTA | upstream-variant-2KB, utr-variant-3-prime | |
| rs114884549 | Likely benign | 1,445,641(+) | GCCCC(A/G)GTGCC | upstream-variant-2KB, utr-variant-3-prime | |
| rs143409179 | Likely benign | 1,445,007(+) | ACACA(-/ACC)ACCAC | upstream-variant-2KB, utr-variant-3-prime, cds-indel | |
| rs150325021 | Likely benign | 1,445,455(+) | CCTGG(A/G)GAGGA | upstream-variant-2KB, utr-variant-3-prime | |
| rs60516531 | Likely benign | 1,446,135(+) | CAGGG(A/G)CCACA | upstream-variant-2KB, utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2422427 | CNV | duplication | 17116639 |
| esv2762143 | CNV | gain | 21179565 |
| nsv457331 | CNV | loss | 19166990 |
| nsv471066 | CNV | loss | 18288195 |
| nsv471068 | CNV | gain | 18288195 |
| nsv571160 | CNV | loss | 21841781 |
| nsv571161 | CNV | gain | 21841781 |
| nsv817713 | CNV | loss | 17921354 |
| nsv819259 | CNV | gain | 19587683 |
| nsv819844 | CNV | gain | 19587683 |
| nsv952899 | CNV | deletion | 24416366 |
Gene Damage Index Score:
7.61;
82.66% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CCDC154 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCDC154
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC154 Gene
Disorders for CCDC154 Gene
Relevant External Links for CCDC154
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CCDC154
No disorders were found for CCDC154 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC154 Gene
Publications for CCDC154 Gene
- Overexpression of a novel osteopetrosis-related gene CCDC154 suppresses cell proliferation by inducing G2/M arrest. (PMID: 22895184) Liao W. … Lu X. (Cell Cycle 2012) 3 4 64
- The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for CCDC154 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CCDC154
- Search Origene for MassSpec and Protein Over-expression Lysates for CCDC154
- Origene Custom Protein Services for CCDC154
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCDC154
- Browse OriGene Inhibitory RNA Products For CCDC154
- OriGene qPCR primer pairs for CCDC154
- OriGene CRISPR knockouts for CCDC154
- OriGene ORF clones in human for CCDC154
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CCDC154
- GenScript: Next-day shipping cDNA ORF clone for CCDC154 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CCDC154
- GenScript Custom Assay Services for CCDC154
- GenScript Custom overexpressing Cell Line Services for CCDC154
- GenScript: Design CRISPR guide RNA sequences for CCDC154
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CCDC154
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CCDC154
- Novus Biologicals proteins for CCDC154
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for CCDC154
- ViGene Biosciences adenoviral particle packaged cDNA for CCDC154 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCDC154 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCDC154 gene
- Search ViGene Biosciences for CCDC154
- Horizon Cell Lines for CCDC154
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC154
- VectorBuilder custom plasmid, inducible vectors for CCDC154
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC154
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CCDC154 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer