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Aliases for CCDC154 Gene

Aliases for CCDC154 Gene

  • Coiled-Coil Domain Containing 154 2 3
  • Coiled-Coil Domain-Containing Protein 154 3
  • Chromosome 16 Open Reading Frame 29 2
  • C16orf29 3

External Ids for CCDC154 Gene

Previous HGNC Symbols for CCDC154 Gene

  • C16orf29

Previous GeneCards Identifiers for CCDC154 Gene

  • GC16M001426
  • GC16M001484
  • GC16M001412

Summaries for CCDC154 Gene

GeneCards Summary for CCDC154 Gene

CCDC154 (Coiled-Coil Domain Containing 154) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC154 Gene

Genomics for CCDC154 Gene

Regulatory Elements for CCDC154 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC154 Gene

1,434,383 bp from pter
1,444,556 bp from pter
10,174 bases
Minus strand

Genomic View for CCDC154 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC154 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC154 Gene

Proteins for CCDC154 Gene

  • Protein details for CCDC154 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 154
    Protein Accession:
    Secondary Accessions:
    • G9JV18

    Protein attributes for CCDC154 Gene

    674 amino acids
    Molecular mass:
    76013 Da
    Quaternary structure:
    No Data Available
    • Overexpression suppresses cell proliferation by inducing G2/M arrest.

    Alternative splice isoforms for CCDC154 Gene


neXtProt entry for CCDC154 Gene

Proteomics data for CCDC154 Gene at MOPED

Post-translational modifications for CCDC154 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC154 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC154 Gene

Domains for CCDC154 Gene

Protein Domains for CCDC154 Gene


Suggested Antigen Peptide Sequences for CCDC154 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC154: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC154 Gene

Function for CCDC154 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC154

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC154 Gene

Localization for CCDC154 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC154 Gene

Early endosome.

Subcellular locations from

Jensen Localization Image for CCDC154 Gene COMPARTMENTS Subcellular localization image for CCDC154 gene
Compartment Confidence
cytosol 2
nucleus 2
endosome 1

Gene Ontology (GO) - Cellular Components for CCDC154 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005768 endosome --
GO:0005769 early endosome IEA --
genes like me logo Genes that share ontologies with CCDC154: view

Pathways for CCDC154 Gene

SuperPathways for CCDC154 Gene

No Data Available

Interacting Proteins for CCDC154 Gene

Gene Ontology (GO) - Biological Process for CCDC154 Gene


No data available for Pathways by source for CCDC154 Gene

Transcripts for CCDC154 Gene

mRNA/cDNA for CCDC154 Gene

(3) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC154 Gene

Coiled-coil domain containing 154:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC154

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC154 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16
SP2: -
SP3: - -
SP5: -

Relevant External Links for CCDC154 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC154 Gene

mRNA expression in normal human tissues for CCDC154 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC154 Gene

This gene is overexpressed in Testis (7.0) and Pituitary (4.1).

Protein differential expression in normal tissues for CCDC154 Gene

This gene is overexpressed in Gallbladder (64.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC154 Gene

SOURCE GeneReport for Unigene cluster for CCDC154 Gene Hs.355232

genes like me logo Genes that share expressions with CCDC154: view

Expression partners for CCDC154 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC154 Gene

Orthologs for CCDC154 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC154 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC154 35
  • 79.01 (n)
  • 68.99 (a)
CCDC154 36
  • 66 (a)
(Canis familiaris)
Mammalia CCDC154 35
  • 76.75 (n)
  • 67.07 (a)
CCDC154 36
  • 67 (a)
(Mus musculus)
Mammalia Ccdc154 35
  • 74.25 (n)
  • 67.97 (a)
Ccdc154 16
Ccdc154 36
  • 66 (a)
(Pan troglodytes)
Mammalia CCDC154 35
  • 97.4 (n)
  • 97 (a)
CCDC154 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Ccdc154 35
  • 75.13 (n)
  • 67.45 (a)
(Monodelphis domestica)
Mammalia CCDC154 36
  • 48 (a)
Species with no ortholog for CCDC154:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC154 Gene

Gene Tree for CCDC154 (if available)
Gene Tree for CCDC154 (if available)

Paralogs for CCDC154 Gene

No data available for Paralogs for CCDC154 Gene

Variants for CCDC154 Gene

Sequence variations from dbSNP and Humsavar for CCDC154 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs760993 -- 1,442,659(+) AGGAA(C/T)GGGAA intron-variant
rs760994 -- 1,443,097(+) AGGCC(A/G)CCCAG intron-variant
rs760995 -- 1,443,129(+) TCTAG(C/T)TGGAC intron-variant
rs909974 -- 1,436,351(+) CACGA(C/T)ACCAG intron-variant
rs1883480 -- 1,443,029(+) CTCGG(C/G)GGGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC154 Gene

Variant ID Type Subtype PubMed ID
esv2422427 CNV Duplication 17116639
nsv471066 CNV Loss 18288195
dgv2505n71 CNV Loss 21882294
dgv2525n71 CNV Loss 21882294
nsv904950 CNV Loss 21882294
nsv904954 CNV Loss 21882294
dgv2527n71 CNV Loss 21882294
dgv2528n71 CNV Loss 21882294
dgv2529n71 CNV Loss 21882294
dgv2530n71 CNV Loss 21882294
dgv2531n71 CNV Loss 21882294
nsv904991 CNV Loss 21882294
nsv457331 CNV Loss 19166990
nsv904993 CNV Gain 21882294
nsv819844 CNV Gain 19587683
nsv819259 CNV Gain 19587683
dgv2532n71 CNV Loss 21882294
dgv2533n71 CNV Loss 21882294
dgv2534n71 CNV Loss 21882294
nsv817713 CNV Loss 17921354
nsv905003 CNV Loss 21882294
nsv905004 CNV Loss 21882294
nsv471068 CNV Gain 18288195

Relevant External Links for CCDC154 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC154 Gene

Disorders for CCDC154 Gene

(1) University of Copenhagen DISEASES for CCDC154 Gene

genes like me logo Genes that share disorders with CCDC154: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for CCDC154 Gene

Publications for CCDC154 Gene

  1. Overexpression of a novel osteopetrosis-related gene CCDC154 suppresses cell proliferation by inducing G2/M arrest. (PMID: 22895184) Liao W. … Lu X. (Cell Cycle 2012) 3 4
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CCDC154 Gene

Sources for CCDC154 Gene

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