CCDC153 Gene
protein-coding GIFtS: 34
GCID: GC11M119060
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coiled-coil domain containing 153
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Aliases
for CCDC153 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 1531 2 | | LOC2831521 | | Coiled-Coil Domain-Containing Protein 1532 |
Export aliases for CCDC153 gene to outside databasesPrevious GC identifers: GC11M118567 GC11M115000 |
Summaries
for CCDC153 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC153 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC153 gene promoter:
STAT1 Elk-1 AP-1 ATF-2 STAT1beta STAT5A STAT1alpha PPAR-gamma1 STAT3 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC153
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC153 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3CCDC153 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M119060: view genomic region
(about GC identifiers)
Start:
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119,060,347 bp from pter |
End:
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119,067,479 bp from pter |
Size:
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7,133 bases |
Orientation:
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minus strand |
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Proteins
for CCDC153 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC153_HUMAN, Q494R4 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 153 Size: 210 amino acids; 23858 DaAlternative splicing: 2 isoforms: Q494R4-1 Q494R4-2 Explore the universe of human proteins at neXtProt for CCDC153: NX_Q494R4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q494R4
CCDC153 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001138490.1
ENSEMBL proteins: ENSP00000423567 ENSP00000445431
Human Recombinant Protein Products:
CCDC153 Antibody Products:
Assay Products for CCDC153: |
Protein
Domains /
Families
for CCDC153 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q494R4 UniProtKB/Swiss-Prot: CC153_HUMAN, Q494R4Similarity: Belongs to the UPF0610 family |
Function
for CCDC153 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC153 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC153
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC153 (NM_001145018) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC153 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC153 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC153 |
|
Pathways & Interactions
for CCDC153 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC153
|
Drugs & Compounds
for CCDC153 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC153
Search CenterWatch for drugs/clinical trials and news about CCDC153 / CC153
|
Transcripts
for CCDC153 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC153 gene (2 alternative transcripts): NM_001033658.1 NM_001145018.1 Unigene Cluster for CCDC153: Coiled-coil domain containing 153 Hs.114777 [show with all ESTs]Unigene Representative Sequence: NM_0011450184 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000503566 ENST00000375140(uc010rze.2) ENST00000447948 ENST00000415318
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC153 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC153
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC153 (NM_001145018) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC153 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC153 |
1 DOTS entry: DT.403154 8 AceView cDNA sequences: BC043548 AA770002 BX113026 BI830079 AI801883 AA782908 AA909102 AA026115
GeneLoc Exon Structure
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Expression
for CCDC153 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC153 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGCGAAGT
About this image
Genevestigator expression for CCDC153
SOURCE GeneReport for Unigene cluster: Hs.114777
SABiosciences Custom PCR Arrays for CCDC153
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC153
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCDC153 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC153 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC153 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC153 |
Orthologs
for CCDC153 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CCDC153 gene from 3/12 species (see all 12) About this table
ENSEMBL Gene Tree for CCDC153 (if available)
TreeFam Gene Tree for CCDC153 (if available) |
Paralogs
for CCDC153 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CCDC153 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC153 (119060347 - 119067479 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CCDC153: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for CCDC153 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CCDC153 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC153 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC153) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for CCDC153 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing CCDC153 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC153 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC153 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC153 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for CCDC153 gene:
Search GeneIP for patents involving CCDC153
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC153 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC153 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC153 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC153 | | | OriGene Protein Over-expression Lysate for CCDC153 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC153 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC153 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC153 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CCDC153 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC153 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC153 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC153 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC153 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC153 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC153 |
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| | | | Search Tocris compounds for CCDC153 |
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 | | | CCDC153 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC153 |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC153 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC153 |
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