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Aliases for CCDC153 Gene

Aliases for CCDC153 Gene

  • Coiled-Coil Domain Containing 153 2 3

External Ids for CCDC153 Gene

Previous GeneCards Identifiers for CCDC153 Gene

  • GC11M118567
  • GC11M119060
  • GC11M115000

Summaries for CCDC153 Gene

GeneCards Summary for CCDC153 Gene

CCDC153 (Coiled-Coil Domain Containing 153) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC153 Gene

Genomics for CCDC153 Gene

Regulatory Elements for CCDC153 Gene

Genomic Location for CCDC153 Gene

Chromosome:
11
Start:
119,189,638 bp from pter
End:
119,206,286 bp from pter
Size:
16,649 bases
Orientation:
Minus strand

Genomic View for CCDC153 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for CCDC153 Gene

Proteins for CCDC153 Gene

  • Protein details for CCDC153 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q494R4-CC153_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 153
    Protein Accession:
    Q494R4

    Protein attributes for CCDC153 Gene

    Size:
    210 amino acids
    Molecular mass:
    23858 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC153 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC153 Gene

Proteomics data for CCDC153 Gene at MOPED

Post-translational modifications for CCDC153 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC153 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC153 Gene

Domains & Families for CCDC153 Gene

Protein Domains for CCDC153 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC153 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q494R4

UniProtKB/Swiss-Prot:

CC153_HUMAN :
  • Belongs to the UPF0610 family.
Family:
  • Belongs to the UPF0610 family.
genes like me logo Genes that share domains with CCDC153: view

No data available for Gene Families for CCDC153 Gene

Function for CCDC153 Gene

Gene Ontology (GO) - Molecular Function for CCDC153 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC153: view

Phenotypes for CCDC153 Gene

GenomeRNAi human phenotypes for CCDC153:
genes like me logo Genes that share phenotypes with CCDC153: view

Animal Model Products

CRISPR Products

miRNA for CCDC153 Gene

miRTarBase miRNAs that target CCDC153

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC153

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC153 Gene

Localization for CCDC153 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC153 Gene COMPARTMENTS Subcellular localization image for CCDC153 gene
Compartment Confidence
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC153 Gene

Pathways & Interactions for CCDC153 Gene

SuperPathways for CCDC153 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC153 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC153 Gene

Drugs & Compounds for CCDC153 Gene

No Compound Related Data Available

Transcripts for CCDC153 Gene

mRNA/cDNA for CCDC153 Gene

(20) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC153 Gene

Coiled-coil domain containing 153:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC153

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC153 Gene

No ASD Table

Relevant External Links for CCDC153 Gene

GeneLoc Exon Structure for
CCDC153
ECgene alternative splicing isoforms for
CCDC153

Expression for CCDC153 Gene

mRNA expression in normal human tissues for CCDC153 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC153 Gene

This gene is overexpressed in Pituitary (x6.1) and Testis (x5.5).

Protein differential expression in normal tissues from HIPED for CCDC153 Gene

This gene is overexpressed in Adipocyte (33.2), Heart (26.9), and Pancreatic juice (8.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCDC153 Gene



SOURCE GeneReport for Unigene cluster for CCDC153 Gene Hs.114777

genes like me logo Genes that share expression patterns with CCDC153: view

Protein tissue co-expression partners for CCDC153 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC153 Gene

Orthologs for CCDC153 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC153 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CCDC153 35
  • 76.88 (n)
  • 73.37 (a)
CCDC153 36
  • 70 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC153 35
  • 81.74 (n)
  • 75.38 (a)
CCDC153 36
  • 54 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc153 35
  • 78.73 (n)
  • 69.85 (a)
Ccdc153 16
Ccdc153 36
  • 69 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CCDC153 35
  • 99.21 (n)
  • 97.62 (a)
CCDC153 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc153 35
  • 78.73 (n)
  • 69.85 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC153 36
  • 59 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC153 35
  • 57.29 (n)
  • 36.68 (a)
CCDC153 36
  • 36 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc153 35
  • 50.17 (n)
  • 39.29 (a)
zebrafish
(Danio rerio)
Actinopterygii ccdc153 35
  • 47.91 (n)
  • 34.17 (a)
ccdc153 36
  • 34 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
OneToOne
Species with no ortholog for CCDC153:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC153 Gene

ENSEMBL:
Gene Tree for CCDC153 (if available)
TreeFam:
Gene Tree for CCDC153 (if available)

Paralogs for CCDC153 Gene

No data available for Paralogs for CCDC153 Gene

Variants for CCDC153 Gene

Sequence variations from dbSNP and Humsavar for CCDC153 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1186369 -- 119,197,472(+) tgcgg(G/T)ggcat upstream-variant-2KB, intron-variant
rs2301574 - 119,193,198(+) TGCTG(C/T)GGGTT missense, reference, synonymous-codon, intron-variant, downstream-variant-500B, nc-transcript-variant
rs7104210 -- 119,203,176(+) tcagg(G/T)tggtc intron-variant, upstream-variant-2KB
rs7105861 -- 119,200,200(+) aggat(C/G)tcttg intron-variant, upstream-variant-2KB
rs7932398 -- 119,201,187(+) gctgc(C/G)caggc intron-variant

Variation tolerance for CCDC153 Gene

Residual Variation Intolerance Score: 89.51% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.33; 76.69% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC153 Gene

HapMap Linkage Disequilibrium report
CCDC153

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC153 Gene

Disorders for CCDC153 Gene

Relevant External Links for CCDC153

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC153
genes like me logo Genes that share disorders with CCDC153: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC153 Gene

Publications for CCDC153 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for CCDC153 Gene

Sources for CCDC153 Gene

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