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Aliases for CCDC150 Gene

Aliases for CCDC150 Gene

  • Coiled-Coil Domain Containing 150 2 3 5

External Ids for CCDC150 Gene

Previous GeneCards Identifiers for CCDC150 Gene

  • GC02P197214
  • GC02P197504
  • GC02P189356

Summaries for CCDC150 Gene

GeneCards Summary for CCDC150 Gene

CCDC150 (Coiled-Coil Domain Containing 150) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC150 Gene

Genomics for CCDC150 Gene

Regulatory Elements for CCDC150 Gene

Enhancers for CCDC150 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F196600 1.5 FANTOM5 Ensembl ENCODE 10.7 -37.8 -37830 2.0 PKNOX1 SIN3A ZBTB40 RAD21 RFX5 RCOR1 FOS CREM THAP11 SP5 CCDC150 HECW2 LOC105373823
GH02F196696 0.9 Ensembl ENCODE 15.9 +57.1 57079 1.0 JUN CEBPB EP300 ARID1B JUND GATA3 ATF3 CEBPA FOSL2 FOS CCDC150 ANKRD44 GC02M196687 ENSG00000252923 LOC100130452
GH02F196293 1.2 Ensembl ENCODE 9.8 -344.9 -344943 2.3 ELF3 HDGF SIN3A ZBTB40 YY1 RFX5 RARA FOS THAP11 MIXL1 CCDC150 HECW2 RN7SL820P LOC105373822
GH02F196398 1.5 FANTOM5 Ensembl ENCODE 6.6 -239.3 -239317 2.6 TBP HDAC1 PKNOX1 ATF1 ARNT TBL1XR1 CREB3L1 RFX5 ZNF366 RCOR1 CCDC150 STK17B LOC105373822 RN7SL820P
GH02F196237 1.6 FANTOM5 Ensembl ENCODE 5.1 -395.0 -394954 14.0 HDGF PKNOX1 ATF1 YY1 CBX5 FOS JUNB TBX21 MAFF SMARCA4 STK17B CCDC150 ENSG00000223466 DNAH7 GC02M196143
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC150 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC150 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000124882 447 1999 CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 CBX5

Genomic Location for CCDC150 Gene

Chromosome:
2
Start:
196,639,554 bp from pter
End:
196,763,490 bp from pter
Size:
123,937 bases
Orientation:
Plus strand

Genomic View for CCDC150 Gene

Genes around CCDC150 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC150 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC150 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC150 Gene

Proteins for CCDC150 Gene

  • Protein details for CCDC150 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCX0-CC150_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 150
    Protein Accession:
    Q8NCX0
    Secondary Accessions:
    • Q6P5U6
    • Q6P663
    • Q8N8V5

    Protein attributes for CCDC150 Gene

    Size:
    1101 amino acids
    Molecular mass:
    128761 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH62658.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC150 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC150 Gene

Post-translational modifications for CCDC150 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC150 Gene

Domains & Families for CCDC150 Gene

Protein Domains for CCDC150 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC150: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC150 Gene

Function for CCDC150 Gene

Gene Ontology (GO) - Molecular Function for CCDC150 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC150: view
genes like me logo Genes that share phenotypes with CCDC150: view

Animal Model Products

miRNA for CCDC150 Gene

miRTarBase miRNAs that target CCDC150

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC150 Gene

Localization for CCDC150 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC150 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC150 Gene

Pathways & Interactions for CCDC150 Gene

SuperPathways for CCDC150 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC150 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC150 Gene

Transcripts for CCDC150 Gene

Unigene Clusters for CCDC150 Gene

Coiled-coil domain containing 150:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC150 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9
SP1: -
SP2: - - - -
SP3:
SP4: -

Relevant External Links for CCDC150 Gene

GeneLoc Exon Structure for
CCDC150
ECgene alternative splicing isoforms for
CCDC150

Expression for CCDC150 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCDC150 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC150 Gene

This gene is overexpressed in Testis (x17.1).

Protein differential expression in normal tissues from HIPED for CCDC150 Gene

This gene is overexpressed in Vitreous humor (29.4), Bone marrow stromal cell (28.7), and Cardia (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC150 Gene



NURSA nuclear receptor signaling pathways regulating expression of CCDC150 Gene:

CCDC150

SOURCE GeneReport for Unigene cluster for CCDC150 Gene:

Hs.132519
genes like me logo Genes that share expression patterns with CCDC150: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CCDC150 Gene

Orthologs for CCDC150 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC150 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC150 34 35
  • 99.3 (n)
dog
(Canis familiaris)
Mammalia CCDC150 34 35
  • 88.39 (n)
mouse
(Mus musculus)
Mammalia Ccdc150 34 16 35
  • 82.2 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc150 34
  • 82.01 (n)
cow
(Bos Taurus)
Mammalia CCDC150 34 35
  • 81.93 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC150 35
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC150 35
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC150 35
  • 50 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc150 34
  • 53.61 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100534986 34
  • 50 (n)
CCDC150 35
  • 23 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1101 35
  • 28 (a)
OneToOne
Species where no ortholog for CCDC150 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC150 Gene

ENSEMBL:
Gene Tree for CCDC150 (if available)
TreeFam:
Gene Tree for CCDC150 (if available)

Paralogs for CCDC150 Gene

Pseudogenes.org Pseudogenes for CCDC150 Gene

genes like me logo Genes that share paralogs with CCDC150: view

No data available for Paralogs for CCDC150 Gene

Variants for CCDC150 Gene

Sequence variations from dbSNP and Humsavar for CCDC150 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10172319 -- 196,721,361(+) ATATA(C/T)ATATA intron-variant
rs10172642 -- 196,691,647(+) ttttt(A/T)aaaac intron-variant
rs10173022 -- 196,725,100(+) CACGT(A/G)GAGAA intron-variant
rs10182221 -- 196,731,116(+) TTTTT(A/G)GATTA intron-variant
rs10190810 -- 196,716,714(+) tatgt(C/G)aaaac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC150 Gene

Variant ID Type Subtype PubMed ID
esv1075947 CNV insertion 17803354
esv3575323 CNV gain 25503493
esv3593891 CNV gain 21293372
esv992569 CNV insertion 20482838
nsv3096 CNV insertion 18451855
nsv997576 CNV gain 25217958
nsv999398 CNV gain 25217958

Variation tolerance for CCDC150 Gene

Residual Variation Intolerance Score: 92.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.17; 84.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC150 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC150

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC150 Gene

Disorders for CCDC150 Gene

Relevant External Links for CCDC150

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC150

No disorders were found for CCDC150 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC150 Gene

Publications for CCDC150 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  3. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for CCDC150 Gene

Sources for CCDC150 Gene

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