Aliases for CCDC15 Gene
External Ids for CCDC15 Gene
- HGNC: 25798
- Entrez Gene: 80071
- Ensembl: ENSG00000149548
- UniProtKB: Q0P6D6
Previous GeneCards Identifiers for CCDC15 Gene
- GC11P124330
- GC11P124824
- GC11P120766
Summaries for CCDC15 Gene
GeneCards Summary for CCDC15 Gene
CCDC15 (Coiled-Coil Domain Containing 15) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC15 Gene
Genomics for CCDC15 Gene
Regulatory Elements for CCDC15 Gene
Enhancers for CCDC15 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CCDC15 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CCDC15 gene promoter:
Regulatory Element Products
Genomic Location for CCDC15 Gene
- Chromosome:
- 11
- Start:
- 124,954,121 bp from pter
- End:
- 125,041,489 bp from pter
- Size:
- 87,369 bases
- Orientation:
- Plus strand
Genomic View for CCDC15 Gene
Genes around CCDC15 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q24.2 by Ensembl
- 11q24.2 by Entrez Gene
- 11q24.2 by HGNC
CCDC15 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCDC15 Gene
Proteins for CCDC15 Gene
-
Protein details for CCDC15 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q0P6D6-CCD15_HUMAN
- Recommended name:
- Coiled-coil domain-containing protein 15
- Protein Accession:
- Q0P6D6
- Q9H8U7
Protein attributes for CCDC15 Gene
- Size:
- 951 amino acids
- Molecular mass:
- 110484 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH18540.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
Protein Expression for CCDC15 Gene
Post-translational modifications for CCDC15 Gene
Other Protein References for CCDC15 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CCDC15
- Novus Biologicals Antibodies for CCDC15
-
Abcam antibodies for CCDC15
- Invitrogen Antibodies for CCDC15
- Search GeneTex for Antibodies for CCDC15
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CCDC15
- Origene Custom Protein Services for CCDC15
- Novus Biologicals proteins for CCDC15
- Search GeneTex for Proteins for CCDC15
-
Abcam proteins for CCDC15
Assay Products
No data available for DME Specific Peptides for CCDC15 Gene
Domains & Families for CCDC15 Gene
Protein Domains for CCDC15 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for CCDC15 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC15 Gene
Function for CCDC15 Gene
Phenotypes for CCDC15 Gene
- GenomeRNAi human phenotypes for CCDC15:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC15
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC15 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC15 gene
- Search ViGene Biosciences for CCDC15
CRISPR Products
-
OriGene CRISPR knockouts for CCDC15
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC15
- GenScript: Design CRISPR guide RNA sequences for CCDC15
miRNA for CCDC15 Gene
- miRTarBase miRNAs that target CCDC15
miRNA Products
- Search ViGene Biosciences for CCDC15
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCDC15
- Browse OriGene Inhibitory RNA Products For CCDC15
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC15 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CCDC15
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC15
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CCDC15
-
ViGene Biosciences adenoviral particle packaged cDNA for CCDC15 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCDC15 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC15 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC15 Gene
Localization for CCDC15 Gene
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| mitochondrion | 3 |
| cytosol | 3 |
| plasma membrane | 2 |
| nucleus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005813 | centrosome | IDA | 21399614 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC15 Gene
Pathways & Interactions for CCDC15 Gene
No Data Available
No data available for Pathways by source and SIGNOR curated interactions for CCDC15 Gene
Transcripts for CCDC15 Gene
mRNA/cDNA for CCDC15 Gene
- (9) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (20) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCDC15 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CCDC15
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCDC15
- GenScript: Design CRISPR guide RNA sequences for CCDC15
miRNA Products
- Search ViGene Biosciences for CCDC15
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCDC15
- Browse OriGene Inhibitory RNA Products For CCDC15
-
ViGene Biosciences ready-to-package AAV shRNAs for CCDC15 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for CCDC15
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC15
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for CCDC15 Gene
mRNA differential expression in normal tissues according to GTEx for CCDC15 Gene
This gene is overexpressed in Testis (x10.9).
This gene is overexpressed in Plasma (61.9) and Brain (7.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC15 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CCDC15 Gene:
CCDC15SOURCE GeneReport for Unigene cluster for CCDC15 Gene:
Hs.287555Primer Products
-
OriGene qPCR primer pairs and template standards for CCDC15
-
OriGene qPCR primer pairs for CCDC15
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC15 Gene
Orthologs for CCDC15 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCDC15 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CCDC15 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CCDC15 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Ccdc15 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccdc15 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | CCDC15 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CCDC15 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CCDC15 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ccdc15 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100333818 34 |
|
||
| CCDC15 35 |
|
OneToOne | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne |
- Species where no ortholog for CCDC15 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CCDC15 Gene
No data available for Paralogs for CCDC15 Gene
Variants for CCDC15 Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs386352386 | Uncertain significance | 124,987,126(+) | TTTTA(C/G)AAAGT | splice-acceptor-variant | |
| rs1000034363 | -- | 124,970,186(+) | TTAGC(C/G)TCTTT | intron-variant | |
| rs1000038016 | -- | 125,009,047(+) | AACCC(C/T)GTCTC | intron-variant | |
| rs1000047309 | -- | 125,016,009(+) | ATAAC(A/G)TACTG | intron-variant | |
| rs1000109721 | -- | 125,009,286(+) | ATGTT(A/G)TTGAC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1770401 | CNV | deletion | 17803354 |
| esv2256616 | CNV | deletion | 18987734 |
| esv2479047 | CNV | deletion | 19546169 |
| esv2745189 | CNV | deletion | 23290073 |
| esv2745190 | CNV | deletion | 23290073 |
| esv2745191 | CNV | deletion | 23290073 |
| esv2745192 | CNV | deletion | 23290073 |
| esv2745193 | CNV | deletion | 23290073 |
| esv3548468 | CNV | deletion | 23714750 |
| esv996549 | CNV | deletion | 20482838 |
| nsv1054682 | CNV | gain | 25217958 |
| nsv1125537 | CNV | tandem duplication | 24896259 |
| nsv1138084 | CNV | deletion | 24896259 |
| nsv1144597 | CNV | deletion | 24896259 |
| nsv39015 | CNV | deletion | 16902084 |
| nsv520010 | CNV | loss | 19592680 |
| nsv957899 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
93.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.98;
84.07% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CCDC15 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCDC15
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC15 Gene
Disorders for CCDC15 Gene
Relevant External Links for CCDC15
No disorders were found for CCDC15 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC15 Gene
Publications for CCDC15 Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 64
- Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication. (PMID: 24613305) Firat-Karalar E.N. … Stearns T. (Curr. Biol. 2014) 3 64
- Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. (PMID: 24324551) Deng X. … Seielstad M. (PLoS ONE 2013) 3 64
Products for CCDC15 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CCDC15
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CCDC15
- Origene Custom Protein Services for CCDC15
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCDC15
- Browse OriGene Inhibitory RNA Products For CCDC15
- OriGene qPCR primer pairs and template standards for CCDC15
- OriGene qPCR primer pairs for CCDC15
- OriGene CRISPR knockouts for CCDC15
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CCDC15
- GenScript: Next-day shipping cDNA ORF clone for CCDC15 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CCDC15
- GenScript Custom Assay Services for CCDC15
- GenScript Custom overexpressing Cell Line Services for CCDC15
- GenScript: Design CRISPR guide RNA sequences for CCDC15
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CCDC15
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CCDC15
- Novus Biologicals proteins for CCDC15
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for CCDC15
- Abcam proteins for CCDC15
- Search for Assays for CCDC15 at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Invitrogen Antibodies for CCDC15
- ViGene Biosciences adenoviral particle packaged cDNA for CCDC15 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCDC15 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCDC15 gene
- Search ViGene Biosciences for CCDC15
- Horizon Cell Lines for CCDC15
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCDC15
- VectorBuilder custom plasmid, inducible vectors for CCDC15
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCDC15
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CCDC15 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer