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Aliases for CCDC15 Gene

Aliases for CCDC15 Gene

  • Coiled-Coil Domain Containing 15 2 3

External Ids for CCDC15 Gene

Previous GeneCards Identifiers for CCDC15 Gene

  • GC11P124330
  • GC11P124824
  • GC11P120766

Summaries for CCDC15 Gene

GeneCards Summary for CCDC15 Gene

CCDC15 (Coiled-Coil Domain Containing 15) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC15 Gene

Genomics for CCDC15 Gene

Regulatory Elements for CCDC15 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC15 Gene

Start:
124,954,121 bp from pter
End:
125,041,489 bp from pter
Size:
87,369 bases
Orientation:
Plus strand

Genomic View for CCDC15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC15 Gene

Proteins for CCDC15 Gene

  • Protein details for CCDC15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0P6D6-CCD15_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 15
    Protein Accession:
    Q0P6D6
    Secondary Accessions:
    • Q9H8U7

    Protein attributes for CCDC15 Gene

    Size:
    951 amino acids
    Molecular mass:
    110484 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH18540.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

neXtProt entry for CCDC15 Gene

Proteomics data for CCDC15 Gene at MOPED

Post-translational modifications for CCDC15 Gene

  • Ubiquitination at Lys128, Lys443, Lys595, Lys725, and Lys848
  • Modification sites at PhosphoSitePlus

Other Protein References for CCDC15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC15 Gene

Domains for CCDC15 Gene

Protein Domains for CCDC15 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC15 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC15: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC15 Gene

Function for CCDC15 Gene

Animal Model Products

CRISPR Products

miRNA for CCDC15 Gene

miRTarBase miRNAs that target CCDC15

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC15 Gene

Localization for CCDC15 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC15 Gene COMPARTMENTS Subcellular localization image for CCDC15 gene
Compartment Confidence
cytoskeleton 5
cytosol 3
plasma membrane 3
mitochondrion 2
nucleus 2

Gene Ontology (GO) - Cellular Components for CCDC15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005813 centrosome IDA 21399614
genes like me logo Genes that share ontologies with CCDC15: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC15 Gene

Pathways for CCDC15 Gene

SuperPathways for CCDC15 Gene

No Data Available

Interacting Proteins for CCDC15 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000341684%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000341684 for CCDC15 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CCDC15 Gene

None

No data available for Pathways by source for CCDC15 Gene

Transcripts for CCDC15 Gene

mRNA/cDNA for CCDC15 Gene

(20) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC15 Gene

Coiled-coil domain containing 15:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC15

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC15 Gene

No ASD Table

Relevant External Links for CCDC15 Gene

GeneLoc Exon Structure for
CCDC15
ECgene alternative splicing isoforms for
CCDC15

Expression for CCDC15 Gene

mRNA expression in normal human tissues for CCDC15 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC15 Gene

This gene is overexpressed in Testis (10.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC15 Gene

SOURCE GeneReport for Unigene cluster for CCDC15 Gene Hs.287555

genes like me logo Genes that share expressions with CCDC15: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC15 Gene

Orthologs for CCDC15 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC15 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC15 35
  • 98.67 (n)
  • 98.21 (a)
CCDC15 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC15 35
  • 77.29 (n)
  • 64.63 (a)
CCDC15 36
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC15 35
  • 78.56 (n)
  • 68.22 (a)
CCDC15 36
  • 61 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc15 35
  • 75.92 (n)
  • 63.62 (a)
Ccdc15 16
Ccdc15 36
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC15 36
  • 27 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 55 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Ccdc15 35
  • 73.92 (n)
  • 63.02 (a)
chicken
(Gallus gallus)
Aves CCDC15 35
  • 57.51 (n)
  • 50 (a)
CCDC15 36
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC15 36
  • 39 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc15 35
  • 58.4 (n)
  • 49.62 (a)
zebrafish
(Danio rerio)
Actinopterygii CCDC15 36
  • 33 (a)
OneToOne
LOC100333818 35
  • 51.56 (n)
  • 42.49 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 26 (a)
OneToOne
Species with no ortholog for CCDC15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC15 Gene

ENSEMBL:
Gene Tree for CCDC15 (if available)
TreeFam:
Gene Tree for CCDC15 (if available)

Paralogs for CCDC15 Gene

No data available for Paralogs for CCDC15 Gene

Variants for CCDC15 Gene

Sequence variations from dbSNP and Humsavar for CCDC15 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs15541 -- 125,041,240(-) CAATA(C/T)ATTTT utr-variant-3-prime
rs1730933 -- 125,009,973(-) acaca(A/C/G/T)gtact intron-variant
rs3809054 -- 124,954,170(-) AAGTA(A/G)ACCGC utr-variant-5-prime
rs3809055 -- 124,954,085(-) CCGGA(A/G)CTGGG upstream-variant-2KB
rs3809056 -- 124,954,054(-) TCGAG(A/C/T)GCCCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CCDC15 Gene

Variant ID Type Subtype PubMed ID
esv2745189 CNV Deletion 23290073
nsv520010 CNV Loss 19592680
esv2745190 CNV Deletion 23290073
esv2479047 CNV Deletion 19546169
esv2256616 CNV Deletion 18987734
esv2745191 CNV Deletion 23290073
esv2745192 CNV Deletion 23290073
nsv39015 CNV Loss 16902084
esv996549 CNV Deletion 20482838
esv1770401 CNV Deletion 17803354
esv2745193 CNV Deletion 23290073

Relevant External Links for CCDC15 Gene

HapMap Linkage Disequilibrium report
CCDC15

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC15 Gene

Disorders for CCDC15 Gene

Relevant External Links for CCDC15

Genetic Association Database (GAD)
CCDC15
Human Genome Epidemiology (HuGE) Navigator
CCDC15
genes like me logo Genes that share disorders with CCDC15: view

No data available for UniProtKB/Swiss-Prot for CCDC15 Gene

Publications for CCDC15 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. (PMID: 21399614) Jakobsen L. … Andersen J.S. (EMBO J. 2011) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for CCDC15 Gene

Sources for CCDC15 Gene

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