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Aliases for CCDC148 Gene

Aliases for CCDC148 Gene

  • Coiled-Coil Domain Containing 148 2 3

External Ids for CCDC148 Gene

Summaries for CCDC148 Gene

GeneCards Summary for CCDC148 Gene

CCDC148 (Coiled-Coil Domain Containing 148) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC148 Gene

Genomics for CCDC148 Gene

Genomic Location for CCDC148 Gene

Start:
158,171,081 bp from pter
End:
158,456,785 bp from pter
Size:
285,705 bases
Orientation:
Minus strand

Genomic View for CCDC148 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC148 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC148 Gene

Regulatory Elements for CCDC148 Gene

Proteins for CCDC148 Gene

  • Protein details for CCDC148 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NFR7-CC148_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 148
    Protein Accession:
    Q8NFR7
    Secondary Accessions:
    • F5H839
    • Q3B7I3
    • Q3B7I4
    • Q3KR41
    • Q4ZG12
    • Q4ZG23
    • Q53TM6
    • Q96BN5
    • Q96LM2

    Protein attributes for CCDC148 Gene

    Size:
    591 amino acids
    Molecular mass:
    71076 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI07598.1; Type=Frameshift; Positions=383; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC148 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC148 Gene

Proteomics data for CCDC148 Gene at MOPED

Post-translational modifications for CCDC148 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC148 Gene

Domains for CCDC148 Gene

Protein Domains for CCDC148 Gene

ProtoNet:
genes like me logo Genes that share domains with CCDC148: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC148 Gene

Function for CCDC148 Gene

Gene Ontology (GO) - Molecular Function for CCDC148 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC148: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC148 Gene

Localization for CCDC148 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC148 Gene COMPARTMENTS Subcellular localization image for CCDC148 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for CCDC148 Gene

Pathways for CCDC148 Gene

SuperPathways for CCDC148 Gene

No Data Available

Interacting Proteins for CCDC148 Gene

Gene Ontology (GO) - Biological Process for CCDC148 Gene

None

No data available for Pathways by source for CCDC148 Gene

Transcripts for CCDC148 Gene

Unigene Clusters for CCDC148 Gene

Coiled-coil domain containing 148:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC148 Gene

No ASD Table

Relevant External Links for CCDC148 Gene

GeneLoc Exon Structure for
CCDC148
ECgene alternative splicing isoforms for
CCDC148

Expression for CCDC148 Gene

mRNA expression in normal human tissues for CCDC148 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC148 Gene

This gene is overexpressed in Kidney - Cortex (4.4) and Testis (4.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC148 Gene

SOURCE GeneReport for Unigene cluster for CCDC148 Gene Hs.668597

genes like me logo Genes that share expressions with CCDC148: view

Orthologs for CCDC148 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC148 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC148 36
  • 98.86 (n)
  • 98.46 (a)
CCDC148 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC148 36
  • 89.57 (n)
  • 85.47 (a)
CCDC148 37
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC148 36
  • 88.7 (n)
  • 84.85 (a)
CCDC148 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc148 36
  • 79.91 (n)
  • 74.14 (a)
Ccdc148 16
Ccdc148 37
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC148 37
  • 55 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC148 37
  • 57 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc148 36
  • 78.48 (n)
  • 73.46 (a)
chicken
(Gallus gallus)
Aves CCDC148 36
  • 64.32 (n)
  • 53 (a)
CCDC148 37
  • 52 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC148 37
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc148 36
  • 60.34 (n)
  • 52.41 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 38 (a)
OneToOne
Species with no ortholog for CCDC148:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC148 Gene

ENSEMBL:
Gene Tree for CCDC148 (if available)
TreeFam:
Gene Tree for CCDC148 (if available)

Paralogs for CCDC148 Gene

No data available for Paralogs for CCDC148 Gene

Variants for CCDC148 Gene

Sequence variations from dbSNP and Humsavar for CCDC148 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs873121 -- 158,275,137(-) CACTT(A/G)TGAGG intron-variant
rs965430 -- 158,254,710(+) ATGAA(A/G)ATAAG intron-variant
rs965431 -- 158,254,741(+) TTCTC(A/G)TTTTT intron-variant
rs965432 -- 158,254,769(+) GAATC(A/G)TCATT intron-variant
rs1000855 -- 158,255,425(-) AGTGT(C/G)CATTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC148 Gene

Variant ID Type Subtype PubMed ID
esv2721019 CNV Deletion 23290073
nsv508876 CNV Insertion 20534489
esv2721020 CNV Deletion 23290073
esv2659913 CNV Deletion 23128226
nsv2992 CNV Insertion 18451855
esv24817 CNV Loss 19812545
nsv875329 CNV Loss 21882294
nsv459885 CNV Loss 19166990
esv272995 CNV Insertion 20981092
esv269335 CNV Insertion 20981092

Relevant External Links for CCDC148 Gene

HapMap Linkage Disequilibrium report
CCDC148
Human Gene Mutation Database (HGMD)
CCDC148

Disorders for CCDC148 Gene

Relevant External Links for CCDC148

Genetic Association Database (GAD)
CCDC148
Human Genome Epidemiology (HuGE) Navigator
CCDC148
genes like me logo Genes that share disorders with CCDC148: view

No data available for UniProtKB/Swiss-Prot for CCDC148 Gene

Publications for CCDC148 Gene

  1. High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. (PMID: 19401682) Maestrini E. … Monaco A.P. (Mol. Psychiatry 2010) 3 49
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3

Products for CCDC148 Gene

Sources for CCDC148 Gene

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