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Aliases for CCDC144A Gene

Aliases for CCDC144A Gene

  • Coiled-Coil Domain Containing 144A 2 3
  • KIAA0565 4

External Ids for CCDC144A Gene

Summaries for CCDC144A Gene

GeneCards Summary for CCDC144A Gene

CCDC144A (Coiled-Coil Domain Containing 144A) is a Protein Coding gene. An important paralog of this gene is POTEJ.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC144A Gene

Genomics for CCDC144A Gene

Genomic Location for CCDC144A Gene

Start:
16,689,537 bp from pter
End:
16,777,881 bp from pter
Size:
88,345 bases
Orientation:
Plus strand

Genomic View for CCDC144A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC144A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC144A Gene

Regulatory Elements for CCDC144A Gene

Proteins for CCDC144A Gene

  • Protein details for CCDC144A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RUR9-C144A_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 144A
    Protein Accession:
    A2RUR9
    Secondary Accessions:
    • O60311
    • Q6ZU57

    Protein attributes for CCDC144A Gene

    Size:
    1427 amino acids
    Molecular mass:
    165125 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA25491.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA25491.2; Type=Frameshift; Positions=1322; Evidence={ECO:0000305}; Sequence=BAC86369.1; Type=Frameshift; Positions=953; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC144A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC144A Gene

Proteomics data for CCDC144A Gene at MOPED

Post-translational modifications for CCDC144A Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys955

Other Protein References for CCDC144A Gene

No data available for DME Specific Peptides for CCDC144A Gene

Domains for CCDC144A Gene

Protein Domains for CCDC144A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

C144A_HUMAN
Family:
  • Belongs to the CCDC144 family.:
    • A2RUR9
genes like me logo Genes that share domains with CCDC144A: view

No data available for Gene Families for CCDC144A Gene

Function for CCDC144A Gene

miRNA for CCDC144A Gene

miRTarBase miRNAs that target CCDC144A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC144A Gene

Localization for CCDC144A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC144A Gene COMPARTMENTS Subcellular localization image for CCDC144A gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for CCDC144A Gene

Pathways for CCDC144A Gene

SuperPathways for CCDC144A Gene

No Data Available

Interacting Proteins for CCDC144A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000353717%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000353717 for CCDC144A Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CCDC144A Gene

None

No data available for Pathways by source for CCDC144A Gene

Transcripts for CCDC144A Gene

mRNA/cDNA for CCDC144A Gene

(5) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC144A Gene

No ASD Table

Relevant External Links for CCDC144A Gene

GeneLoc Exon Structure for
CCDC144A
ECgene alternative splicing isoforms for
CCDC144A

Expression for CCDC144A Gene

mRNA expression in normal human tissues for CCDC144A Gene

mRNA differential expression in normal tissues according to GTEx for CCDC144A Gene

This gene is overexpressed in Testis (20.3), Brain - Cerebellum (8.2), and Brain - Cerebellar Hemisphere (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC144A Gene

genes like me logo Genes that share expressions with CCDC144A: view

Orthologs for CCDC144A Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC144A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 14 (a)
ManyToMany
CCDC144A 36
  • 98.86 (n)
  • 97.81 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 32 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 41 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Ccdc144b 37
  • 40 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 23 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 24 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 37
  • 19 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 33 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ANKRD7 37
  • 15 (a)
OneToMany
Species with no ortholog for CCDC144A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC144A Gene

ENSEMBL:
Gene Tree for CCDC144A (if available)
TreeFam:
Gene Tree for CCDC144A (if available)

Paralogs for CCDC144A Gene

genes like me logo Genes that share paralogs with CCDC144A: view

Variants for CCDC144A Gene

Sequence variations from dbSNP and Humsavar for CCDC144A Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs540206 -- 16,773,173(-) ACATG(C/T)CTGGC intron-variant
rs650544 -- 16,772,961(-) CTTCA(C/T)TCATT intron-variant
rs744526 -- 16,746,332(-) GAAAA(G/T)AAACG intron-variant
rs778667 -- 16,766,070(+) agggg(G/T)agaca intron-variant
rs778676 -- 16,757,407(-) tccag(A/G)agcat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC144A Gene

Variant ID Type Subtype PubMed ID
dgv928e1 CNV Complex 17122850
dgv3064n71 CNV Gain 21882294
dgv929e1 CNV Complex 17122850
esv2635467 CNV Loss 19546169
nsv833378 CNV Gain 17160897
nsv111702 CNV Insertion 16902084
dgv3065n71 CNV Gain 21882294
nsv442737 CNV CNV 18776908
nsv9497 CNV Loss 18304495

Relevant External Links for CCDC144A Gene

HapMap Linkage Disequilibrium report
CCDC144A

Disorders for CCDC144A Gene

No disorders were found for CCDC144A Gene.

No data available for UniProtKB/Swiss-Prot for CCDC144A Gene

Publications for CCDC144A Gene

  1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4
  2. Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs. (PMID: 11997339) Park S.S. … Lupski J.R. (Genome Res. 2002) 2 3
  3. Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells. (PMID: 18655026) Tan F. … Peng X. (Proteomics 2008) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for CCDC144A Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate CCDC144A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC144A
    • Block miRNA regulation of CCDC144A using miScript Target Protectors

    Sources for CCDC144A Gene

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