CCDC144A Gene
protein-coding GIFtS: 35
GCID: GC17P016592
|
|
coiled-coil domain containing 144A
| |
Aliases
for CCDC144A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 144A1 2 | | KIAA05651 3 | | FLJ439831 | | Coiled-Coil Domain-Containing Protein 144A2 |
Export aliases for CCDC144A gene to outside databasesPrevious GC identifers: GC17P016539 GC17P016460 |
Summaries
for CCDC144A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC144A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC144A gene promoter:
Oct-B1 GR oct-B3 oct-B2 GR-beta POU2F2 POU2F1 POU2F1a SEF-1 (1) GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC144A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC144A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.2CCDC144A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P016592: view genomic region
(about GC identifiers)
Start:
|
16,592,851 bp from pter |
End:
|
16,707,767 bp from pter |
Size:
|
114,917 bases |
Orientation:
|
plus strand |
|
Proteins
for CCDC144A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: C144A_HUMAN, A2RUR9 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 144A Size: 1427 amino acids; 165125 Da
Sequence caution: Sequence=BAA25491.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=BAA25491.2; Type=Frameshift; Positions=1322; Sequence=BAC86369.1; Type=Frameshift; Positions=953;
Secondary accessions: O60311 Q6ZU57Alternative splicing: 3 isoforms: A2RUR9-1 A2RUR9-2 A2RUR9-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CCDC144A: NX_A2RUR9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A2RUR9
CCDC144A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055510.1
ENSEMBL proteins: ENSP00000344740 ENSP00000382215 ENSP00000353717 ENSP00000353685 ENSP00000398774 ENSP00000465529 ENSP00000439262 ENSP00000394201
Human Recombinant Protein Products:
CCDC144A Antibody Products:
Assay Products for CCDC144A: |
Protein
Domains /
Families
for CCDC144A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCDC144A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry A2RUR9ProtoNet protein and cluster: A2RUR9 UniProtKB/Swiss-Prot: C144A_HUMAN, A2RUR9Similarity: Belongs to the CCDC144 family |
Function
for CCDC144A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC144A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC144A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC144A (NM_014695) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC144A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC144A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC144A |
|
Pathways & Interactions
for CCDC144A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC144A
|
Drugs & Compounds
for CCDC144A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC144A
Search CenterWatch for drugs/clinical trials and news about CCDC144A / C144A
|
Transcripts
for CCDC144A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC144A gene: NM_014695.1 15 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000478303 ENST00000340621 ENST00000436374 ENST00000399273 ENST00000399264
ENST00000360524(uc002gqk.1) ENST00000360495 ENST00000420937 ENST00000428950
ENST00000328495 ENST00000482264 ENST00000463809 ENST00000470068(uc002gql.1)
ENST00000443444 ENST00000456009
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC144A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC144A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC144A (NM_014695) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC144A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC144A |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC144A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CCDC144A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC144A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC144A |
1 AceView cDNA sequence: BU184471
GeneLoc Exon Structure
|
Expression
for CCDC144A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC144A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See CCDC144A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC144A
SABiosciences Custom PCR Arrays for CCDC144A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC144A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CCDC144A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC144A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC144A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC144A |
Orthologs
for CCDC144A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CCDC144A gene from 3/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ANKRD626 |
Uncharacterized protein |
28(a) |
1 → many |
1(26091172-26138404) |
lizard
(Anolis carolinensis) |
Reptilia |
ANKRD626 |
-- |
11(a) |
1 → many |
GL344195.1(39104-48393) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:ch211-272n13.36 |
si:ch211-272n13.3 |
13(a) |
1 → many |
25(3581527-3655709) |
ENSEMBL Gene Tree for CCDC144A (if available)
TreeFam Gene Tree for CCDC144A (if available) |
Paralogs
for CCDC144A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCDC144A gene
- POTEF2 POTEI2 ANKRD30A2 ANKRD362 ANKRD72 POTEB2 ANKRD30BL2 ANKRD20A32
- POTEH2 ENSG000001552822 ANKRD30B2 ENSG000002663022 ANKRD36C2 POTEJ2 POTEC2 ANKRD20A22
- POTEG2 ANKRD262 ANKRD622 ANKRD18A2 ENSG000001882192 POTEM2 ANKRD20A12 LOC1009963312
- POTED2 ANKRD20A42 ANKRD18B2 LOC1002889662
11 SIMAP similar genes for CCDC144A using alignment to 7 protein entries: C144A_HUMAN (see all proteins):CCDC144B CCDC144NL DKFZp781D1722 LOC254750 CCDC144C ANKRD36BP1
LOC644249 ANKRD62 PRED4 ANKRD18B ANKRD26
CCDC144A for paralogs About GeneDecksing
5/56 Pseudogenes.org Pseudogenes for CCDC144A (see all 56)
PGOHUM00000238377 PGOHUM00000248296 PGOHUM00000248308 PGOHUM00000248537 PGOHUM00000247720
|
Genomic Variants
for CCDC144A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC144A (16592851 - 16707767 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for CCDC144A
4 CNVs: 4023 102417 38953 3139
1 Indel: 33642 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC144A |
|
Disorders
/ Diseases
for CCDC144A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCDC144A for disorders About GeneDecksing
1  disease for CCDC144A: About MalaCardssmith-magenis syndrome
Export disorders for CCDC144A gene to outside databases
|
Publications
for CCDC144A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC144A gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC144A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2, 3 Nagase T....Ohara O. (1998)
- Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs. (PubMed id 11997339)1, 3 Park S.S....Lupski J.R. (2002)
- Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells. (PubMed id 18655026)2 Tan F....Peng X. (2008)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for CCDC144A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC144A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC144A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing CCDC144A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC144A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC144A gene:
Search GeneIP for patents involving CCDC144A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC144A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC144A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC144A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC144A | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC144A | | OriGene 3'-UTR Clone for CCDC144A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC144A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC144A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC144A | | OriGene Custom Protein Services for CCDC144A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC144A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC144A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC144A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC144A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC144A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC144A |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | CCDC144A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC144A |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC144A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC144A |
|
|
|
|
