CCDC142 Gene
protein-coding GIFtS: 37
GCID: GC02M074703
|
|
coiled-coil domain containing 142
| |
Aliases
for CCDC142 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 1421 2 | | FLJ143971 | | Coiled-Coil Domain-Containing Protein 1422 |
Export aliases for CCDC142 gene to outside databasesPrevious GC identifers: GC02M074555 GC02M074436 |
Summaries
for CCDC142 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC142 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC142 gene promoter:
E2F-4 E2F-3a NF-1/L NF-1 E2F-5 STAT1 E2F-2 E2F-1 E2F Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC142
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC142 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p13.1 Ensembl cytogenetic band: 2p13.1 HGNC cytogenetic band: 2p13.1CCDC142 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M074703: view genomic region
(about GC identifiers)
Start:
|
74,699,113 bp from pter |
End:
|
74,710,535 bp from pter |
Size:
|
11,423 bases |
Orientation:
|
minus strand |
|
Proteins
for CCDC142 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC142_HUMAN, Q17RM4 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 142 Size: 750 amino acids; 81643 Da
Sequence caution: Sequence=BAC11474.1; Type=Erroneous initiation;
Secondary accessions: B7ZKV5 Q8NBJ3 Q8NBV2 Q96KA7Alternative splicing: 3 isoforms: Q17RM4-1 Q17RM4-2 Q17RM4-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CCDC142: NX_Q17RM4
CCDC142 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_116168.3
ENSEMBL proteins: ENSP00000415532 ENSP00000377537 ENSP00000290418
Human Recombinant Protein Products:
CCDC142 Antibody Products:
Assay Products for CCDC142: |
Protein
Domains /
Families
for CCDC142 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCDC142 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q17RM4ProtoNet protein and cluster: Q17RM4 |
Function
for CCDC142 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC142 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC142
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC142 (NM_032779) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC142 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC142 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC142 |
2 GenomeRNAi human phenotypes for CCDC142:
|
Pathways & Interactions
for CCDC142 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC142
|
Drugs & Compounds
for CCDC142 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC142
Search CenterWatch for drugs/clinical trials and news about CCDC142 / CC142
|
Transcripts
for CCDC142 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC142 gene: NM_032779.3 Unigene Cluster for CCDC142: Coiled-coil domain containing 142 Hs.430199 [show with all ESTs]Unigene Representative Sequence: NM_0327799 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000454193 ENST00000393965(uc002slo.3 uc002slq.3 uc002slr.3 uc002slp.2)
ENST00000290418 ENST00000473278 ENST00000486335 ENST00000497232 ENST00000471713
ENST00000474681 ENST00000472962
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC142 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC142
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC142 (NM_032779) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC142 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC142 |
Additional cDNA sequence: AK027303.1 AK075543.1 BC117269.1 BC143398.1 BC143399.1 8 DOTS entries: DT.70100578 DT.120931224 DT.120931180 DT.100748112 DT.100741615 DT.91845890 DT.95199100 DT.97842869 24/153 AceView cDNA sequences (see all 153): AK075209 AI564950 AW081076 BQ016433 AA424037 BI858166 BM903971 BM695872 BM707017 CK904548 AW166509 BF941879 BQ014848 AI268599 AI420098 AI493696 AW163645 BC012163 CB216111 AI149851 AW157651 BU075817 AW004617 BU190829
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC142 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | ^ | 13a | · | 13b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | |
ECgene alternative splicing isoforms for CCDC142
|
Expression
for CCDC142 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC142 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGTTGTGCCG
About this image
See CCDC142 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC142
SOURCE GeneReport for Unigene cluster: Hs.430199
SABiosciences Custom PCR Arrays for CCDC142
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC142
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCDC142 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC142 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC142 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC142 |
Orthologs
for CCDC142 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CCDC142 gene from 3/10 species (see all 10) About this table
ENSEMBL Gene Tree for CCDC142 (if available)
TreeFam Gene Tree for CCDC142 (if available) |
Paralogs
for CCDC142 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CCDC142 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC142 (74699113 - 74710535 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CCDC142
3 CNVs: 50556 3366 50558 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CCDC142 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CCDC142 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC142 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC142) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- [Novel bidirectional promoter from human genome]. (PubMed id 21790010)1 Orekhova A.S....Rubtsov P.M. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for CCDC142 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC142 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC142 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC142 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC142 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC142 gene:
Search GeneIP for patents involving CCDC142
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC142 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC142 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC142 | | | OriGene Protein Over-expression Lysate for CCDC142 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC142 | | OriGene 3'-UTR Clone for CCDC142 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC142 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC142 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC142 | | OriGene Custom Protein Services for CCDC142 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC142 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC142 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC142 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC142 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC142 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC142 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCDC142 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CCDC142 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC142 |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC142 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC142 |
|
|
|
|
