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Aliases for CCDC142 Gene

Aliases for CCDC142 Gene

  • Coiled-Coil Domain Containing 142 2 3 5

External Ids for CCDC142 Gene

Previous GeneCards Identifiers for CCDC142 Gene

  • GC02M074555
  • GC02M074703
  • GC02M074436

Summaries for CCDC142 Gene

GeneCards Summary for CCDC142 Gene

CCDC142 (Coiled-Coil Domain Containing 142) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC142 Gene

Genomics for CCDC142 Gene

Regulatory Elements for CCDC142 Gene

Enhancers for CCDC142 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around CCDC142 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC142 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for CCDC142 Gene

74,471,986 bp from pter
74,483,408 bp from pter
11,423 bases
Minus strand

Genomic View for CCDC142 Gene

Genes around CCDC142 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC142 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC142 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC142 Gene

Proteins for CCDC142 Gene

  • Protein details for CCDC142 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 142
    Protein Accession:
    Secondary Accessions:
    • B7ZKV5
    • Q8NBJ3
    • Q8NBV2
    • Q96KA7

    Protein attributes for CCDC142 Gene

    750 amino acids
    Molecular mass:
    81643 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC11474.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC142 Gene


neXtProt entry for CCDC142 Gene

Post-translational modifications for CCDC142 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC142 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC142 Gene

Domains & Families for CCDC142 Gene

Protein Domains for CCDC142 Gene


Suggested Antigen Peptide Sequences for CCDC142 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC142: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC142 Gene

Function for CCDC142 Gene

genes like me logo Genes that share phenotypes with CCDC142: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC142 Gene

Localization for CCDC142 Gene

Subcellular locations from

Jensen Localization Image for CCDC142 Gene COMPARTMENTS Subcellular localization image for CCDC142 gene
Compartment Confidence
extracellular 2
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC142 Gene

Pathways & Interactions for CCDC142 Gene

SuperPathways for CCDC142 Gene

No Data Available

Interacting Proteins for CCDC142 Gene

Gene Ontology (GO) - Biological Process for CCDC142 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC142 Gene

Drugs & Compounds for CCDC142 Gene

No Compound Related Data Available

Transcripts for CCDC142 Gene

Unigene Clusters for CCDC142 Gene

Coiled-coil domain containing 142:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC142 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b
SP1: - - - -
SP5: -
SP7: - -

Relevant External Links for CCDC142 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC142 Gene

mRNA expression in normal human tissues for CCDC142 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC142 Gene

Protein tissue co-expression partners for CCDC142 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CCDC142 Gene:


SOURCE GeneReport for Unigene cluster for CCDC142 Gene:

genes like me logo Genes that share expression patterns with CCDC142: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC142 Gene

Orthologs for CCDC142 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC142 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC142 34
  • 82.99 (n)
  • 77.34 (a)
CCDC142 35
  • 75 (a)
(Canis familiaris)
Mammalia CCDC142 34
  • 84.75 (n)
  • 78.41 (a)
CCDC142 35
  • 78 (a)
(Mus musculus)
Mammalia Ccdc142 34
  • 76.14 (n)
  • 73.26 (a)
Ccdc142 16
Ccdc142 35
  • 72 (a)
(Pan troglodytes)
Mammalia CCDC142 34
  • 99.28 (n)
  • 99.19 (a)
CCDC142 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc142 34
  • 76.65 (n)
  • 73.4 (a)
(Monodelphis domestica)
Mammalia CCDC142 35
  • 54 (a)
(Anolis carolinensis)
Reptilia CCDC142 35
  • 35 (a)
(Danio rerio)
Actinopterygii CCDC142 35
  • 21 (a)
Species where no ortholog for CCDC142 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC142 Gene

Gene Tree for CCDC142 (if available)
Gene Tree for CCDC142 (if available)

Paralogs for CCDC142 Gene

No data available for Paralogs for CCDC142 Gene

Variants for CCDC142 Gene

Sequence variations from dbSNP and Humsavar for CCDC142 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs13385919 - 74,475,629(+) GAAGC(C/T)GCCAG reference, missense
rs11676733 -- 74,476,194(+) TTGAG(A/G)CAGAG intron-variant
rs5832132 -- 74,477,669(+) TGGAG(-/CGTT)CGTTC intron-variant
rs6759423 -- 74,477,999(+) AAAAa(A/T)atata intron-variant
rs7561795 -- 74,480,101(+) tctaa(C/T)gaaat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC142 Gene

Variant ID Type Subtype PubMed ID
esv2759061 CNV loss 17122850
nsv1127734 CNV deletion 24896259
nsv458185 CNV loss 19166990
nsv515851 CNV loss 19592680
nsv582214 CNV loss 21841781

Variation tolerance for CCDC142 Gene

Residual Variation Intolerance Score: 79.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.99; 60.08% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC142 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC142 Gene

Disorders for CCDC142 Gene

Relevant External Links for CCDC142

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC142 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC142 Gene

Publications for CCDC142 Gene

  1. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. [Novel bidirectional promoter from human genome]. (PMID: 21790010) Orekhova A.S. … Rubtsov P.M. (Mol. Biol. (Mosk.) 2011) 3 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for CCDC142 Gene

Sources for CCDC142 Gene

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