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CCDC141 Gene

protein-coding   GIFtS: 46
GCID: GC02M179694

Coiled-Coil Domain Containing 141

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Coiled-Coil Domain Containing 1411 2
Coiled-Coil Protein Associated With Myosin II And DISC11 2
CAMDI2
Coiled-Coil Domain-Containing Protein 1412

External Ids:    HGNC: 268211   Entrez Gene: 2850252   Ensembl: ENSG000001634927   UniProtKB: Q6ZP823   

Export aliases for CCDC141 gene to outside databases

Previous GC identifers: GC02M179407 GC02M171562


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CCDC141 Gene:
CCDC141 (coiled-coil domain containing 141) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC141 gene promoter:
         GR   SRY   HSF2   GR-alpha   LCR-F1   Pax-4a   Nkx5-1   RORalpha2   FOXL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC141 promoter sequence
   Search Chromatin IP Primers for CCDC141

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC141


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.2   Ensembl cytogenetic band:  2q31.2   HGNC cytogenetic band: 2q31.2

CCDC141 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC141 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M179694:  view genomic region     (about GC identifiers)

Start:
179,694,484 bp from pter      End:
179,914,813 bp from pter
Size:
220,330 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CC141_HUMAN, Q6ZP82 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 141  
Size: 875 amino acids; 100581 Da
Sequence caution: Sequence=AAX88845.1; Type=Erroneous gene model prediction; Sequence=BAC04869.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAC04869.1; Type=Miscellaneous discrepancy;
Note=Contaminating sequence;
Secondary accessions: Q8N8H3
Alternative splicing: 2 isoforms:  Q6ZP82-1   Q6ZP82-2   

Explore the universe of human proteins at neXtProt for CCDC141: NX_Q6ZP82

Explore proteomics data for CCDC141 at MOPED


See CCDC141 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_775919.3  
ENSEMBL proteins: 
 ENSP00000344627   ENSP00000390190   ENSP00000388745   ENSP00000386503   ENSP00000395995  
 ENSP00000295723  

CCDC141 Human Recombinant Protein Products:

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Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for CCDC141 

CCDC141 Antibody Products:

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Search eBioscience for ELISAs for CCDC141 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

2 InterPro protein domains:
 IPR013783 Ig-like_fold
 IPR007110 Ig-like_dom

Graphical View of Domain Structure for InterPro Entry Q6ZP82

ProtoNet protein and cluster: Q6ZP82

UniProtKB/Swiss-Prot: CC141_HUMAN, Q6ZP82
Similarity: Contains 1 Ig-like (immunoglobulin-like) domain


Find genes that share domains with CCDC141           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000166nucleotide binding ----
GO:0005515protein binding IPI12812986
     
Find genes that share ontologies with CCDC141           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC141
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC141

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC141
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC141

miRNA
Products:
    
miRTarBase miRNAs that target CCDC141:
hsa-mir-335-5p (MIRT018715)

Block miRNA regulation of human, mouse, rat CCDC141 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate CCDC141 (see all 40):
hsa-miR-4291 hsa-miR-607 hsa-let-7d hsa-miR-578 hsa-miR-105 hsa-let-7g hsa-miR-183* hsa-let-7a
SwitchGear 3'UTR luciferase reporter plasmidCCDC141 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CCDC141
Predesigned siRNA for gene silencing in human, mouse, rat CCDC141

Gene Editing
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OriGene clones in human, mouse for CCDC141 (see all 6)
OriGene ORF clones in mouse, rat for CCDC141
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CCDC141 (NM_173648)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC141
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC141

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC141


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
nucleus2
golgi apparatus1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC141
Interactions:

    Search GeneGlobe Interaction Network for CCDC141

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for CCDC141 (Q6ZP821, 3 ENSP000003446274) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
DISC1Q9NRI51, 3, ENSP000003555964EBI-928795,EBI-529989 I2D: score=2 STRING: ENSP00000355596
--ENSP000003936424STRING: ENSP00000393642
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CCDC141 (CC141)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for CCDC141 gene: 
NM_173648.3  

Unigene Cluster for CCDC141:

Coiled-coil domain containing 141
Hs.324341  [show with all ESTs]
Unigene Representative Sequence: NM_173648
9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000472828 ENST00000480419 ENST00000343876 ENST00000443758 ENST00000446116
ENST00000409284(uc002ung.3) ENST00000498142 ENST00000420890(uc002une.2)
ENST00000295723(uc002unf.1)
miRNA
Products:
     
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Selected qRT-PCR Assays for microRNAs that regulate CCDC141 (see all 40):
hsa-miR-4291 hsa-miR-607 hsa-let-7d hsa-miR-578 hsa-miR-105 hsa-let-7g hsa-miR-183* hsa-let-7a
SwitchGear 3'UTR luciferase reporter plasmidCCDC141 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CCDC141
Predesigned siRNA for gene silencing in human, mouse, rat CCDC141
Clone
Products:
     
OriGene clones in human, mouse for CCDC141 (see all 6)
OriGene ORF clones in mouse, rat for CCDC141
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CCDC141 (NM_173648)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC141
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC141
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for CCDC141
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC141
  QuantiTect SYBR Green Assays in human, mouse, rat CCDC141
  QuantiFast Probe-based Assays in human, mouse, rat CCDC141

Additional mRNA sequence: 

AK096821.1 AK129847.1 AL832777.1 BC108697.1 BC115378.2 BX649042.1 

7 DOTS entries:

DT.91676964  DT.101981652  DT.91748373  DT.99946523  DT.100734763  DT.86856247  DT.95079038 

Selected AceView cDNA sequences (see all 29):

BF792488 BM723756 AA447398 BF792795 CF552536 NM_173648 AK129847 BU682794 
BX649042 AA447397 AL589419 AL599223 AL832777 BV182329 BM480069 BX096872 
BM679954 BF791356 BX502855 BX489839 AK096821 CD172530 AA093393 BF968135 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CCDC141 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
CCDC141 Expression
About this image


CCDC141 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 8) fully expand
 
 Brain (Nervous System)    fully expand to see all 4 entries
         Adult Endothelial Cells Blood Brain Barrier
         Oligodendrocyte progenitor cells
 
 Endothelium (Cardiovascular System)    fully expand to see all 3 entries
         Adult Endothelial Cells Blood Brain Barrier
 
 Heart (Cardiovascular System)    fully expand to see all 2 entries
         Cardiac Fibroblasts Myocardium
 
 Fibroblasts
         Cardiac Fibroblasts Myocardium
 
 Testis (Reproductive System)
         Testicular Interstitial Cells Testis Interstitium
CCDC141 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CCDC141 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.324341
    Custom PCR Arrays for CCDC141
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for CCDC141
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC141
QuantiTect SYBR Green Assays in human, mouse, rat CCDC141
QuantiFast Probe-based Assays in human, mouse, rat CCDC141
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC141

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CCDC141 gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Ccdc1411 , 5 coiled-coil domain containing 1411, 5 80.1(n)1
72.86(a)1
  2 (45.38 cM)5
5454281  NM_001025576.31  NP_001020747.21 
 770099025 
chicken
(Gallus gallus)
Aves CCDC1411 coiled-coil domain containing 141 65.37(n)
54.44(a)
  770766  XM_001234092.3  XP_001234093.3 
lizard
(Anolis carolinensis)
Reptilia CCDC1416
coiled-coil domain containing 141
69(a)
1 ↔ 1
GL343320.1(409277-549012)
tropical clawed frog
(Xenopus tropicalis)
Amphibia ccdc1411 coiled-coil domain containing 141 57.86(n)
46.49(a)
  100485826  XM_002935686.2  XP_002935732.1 
zebrafish
(Danio rerio)
Actinopterygii si:dkeyp-122a11.11 si:dkeyp-122a11.1 53.26(n)
42.49(a)
  553274  XM_005167916.1  XP_005167973.1 


ENSEMBL Gene Tree for CCDC141 (if available)
TreeFam Gene Tree for CCDC141 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CCDC141 gene
2 SIMAP similar genes for CCDC141 using alignment to 7 protein entries:     CC141_HUMAN (see all proteins):
KIAA0992    MUSK

Find genes that share paralogs with CCDC141           About GenesLikeMe


1 Pseudogenes.org Pseudogene for CCDC141
PGOHUM00000259770


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CCDC141 (see all 4649)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs681337451,2
C--171642099(+) GGACA-/AAGATA
        
GCCCA
1 -- int11Minor allele frequency- AAGATA:0.00NA 2
rs9904931,2
C,H--179694102(+) CCAAAC/TGCTCA 1 -- ds500117Minor allele frequency- T:0.00NS EA NA WA CSA 796
rs800403321,2
F--179694229(+) GGAGAT/CTCATG 1 -- ds50011Minor allele frequency- C:0.02EA 120
rs1867619151,2
--179694241(+) AAAAAC/GGCCAA 1 -- ds50010--------
rs1140097511,2
C,F--179694368(+) ACACTT/CTCATT 1 -- ds50011Minor allele frequency- C:0.07WA 118
rs1924353901,2
--179694379(+) TAAGTC/TAACGC 1 -- ds50010--------
rs730403541,2
C,F--179694382(+) GTCAAC/TGCAAA 1 -- ds50012Minor allele frequency- T:0.04WA 120
rs1453491251,2
--179694384(+) CAACGC/TAAATC 1 -- ds50010--------
rs1160625171,2
C,F--179694420(+) ATTCCG/ACTTAT 1 -- ds50011Minor allele frequency- A:0.01NA 120
rs759934411,2
C,F--179694439(+) GAAAAC/TAGTCT 1 -- ds50011Minor allele frequency- T:0.03NA 120

HapMap Linkage Disequilibrium report for CCDC141 (179694484 - 179914813 bp)

Structural Variations
     Database of Genomic Variants (DGV) 10 variations for CCDC141:    About this table    
Variant IDTypeSubtypePubMed ID
nsv3059CNV Insertion18451855
esv270025CNV Insertion20981092
nsv875455CNV Loss21882294
dgv4373n71CNV Loss21882294
nsv521818CNV Loss19592680
nsv875456CNV Loss21882294
nsv508184CNV Loss20534489
dgv4372n71CNV Loss21882294
dgv4374n71CNV Loss21882294
nsv834470CNV Gain17160897

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CCDC141
DNA2.0 Custom Variant and Variant Library Synthesis for CCDC141

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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Find genes that share disorders with CCDC141           About GenesLikeMe

Genetic Association Database (GAD): CCDC141
Human Genome Epidemiology (HuGE) Navigator: CCDC141 (1 document)

Export disorders for CCDC141 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CCDC141 gene integrated from 10 sources:
(articles sorted by number of sources associating them with CCDC141)
    Utopia: connect your pdf to the dynamic
world of online information

  1. CAMDI, a novel disrupted in schizophrenia 1 (DISC1)-binding protein, is required for radial migration. (PubMed id 20956536)1, 3 Fukuda T....Yanagi S. (J. Biol. Chem. 2010)
  2. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PubMed id 19536175)1, 4 Ehret G.B....Chakravarti A. (Eur. J. Hum. Genet. 2009)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. (PubMed id 23583979)1 den Hoed M....Loos R.J. (Nat. Genet. 2013)
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
  6. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. (PubMed id 12812986)1 Morris J.A.... Austin C.P. (Hum. Mol. Genet. 2003)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 285025 HGNC: 26821 AceView: FLJ39502 Ensembl:ENSG00000163492 euGenes: HUgn285025
ECgene: CCDC141 H-InvDB: CCDC141

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CCDC141 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CCDC141 gene:
Search GeneIP for patents involving CCDC141

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 OriGene Antibodies for CCDC141   OriGene RNAi products in human, mouse, rat for CCDC141  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for CCDC141  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for CCDC141  
 OriGene qSTAR qPCR primer pairs in human, mouse for CCDC141   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for CCDC141   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CCDC141   OriGene Custom Protein Services for CCDC141  

 
 
 Block miRNA regulation of human, mouse, rat CCDC141 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CCDC141
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC141 Predesigned siRNA for gene silencing in human, mouse, rat CCDC141
 QuantiFast Probe-based Assays in human, mouse, rat CCDC141 QuantiTect SYBR Green Assays in human, mouse, rat CCDC141
 Custom PCR Arrays for CCDC141 Search Chromatin IP Primers for CCDC141
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC141  Search GeneGlobe Interaction Network for CCDC141
 Regulatory tfbs in CCDC141 promoter
 GenScript Custom Purified and Recombinant Proteins Services for CCDC141 GenScript cDNA clones with any tag delivered in your preferred vector for CCDC141
 GenScript Custom Assay Services for CCDC141 GenScript Custom overexpressing Cell Line Services for CCDC141
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
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 Search Tocris compounds for CCDC141 (CC141)
 Browse Sino Biological Proteins
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 4000+ Proteins
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 Protein Production Services
 Transfection Reagents
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 CCDC141 antibodies
 CCDC141 lysates
 Antibodies for CCDC141
 See all of Abcam's Antibodies, Kits and Proteins for CCDC141
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC141
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC141
 SwitchGear 3'UTR luciferase reporter plasmids for CCDC141
 SwitchGear Promoter luciferase reporter plasmids for CCDC141
 ThermoFisher Antibodies for CCDC141
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC141
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC141
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC141
 LSBio Antibodies in human, mouse, rat for CCDC141
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for CCDC141
  Search eBioscience for proteins for CCDC141
  Search eBioscience for elisas for CCDC141
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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