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CCDC14 Gene

protein-coding   GIFtS: 51
GCID: GC03M123616

Coiled-Coil Domain Containing 14

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Coiled-Coil Domain Containing 141 2
Coiled-Coil Domain-Containing Protein 142

External Ids:    HGNC: 257661   Entrez Gene: 647702   Ensembl: ENSG000001754557   UniProtKB: Q49A883   
ORGUL members:         

Export aliases for CCDC14 gene to outside databases

Previous GC identifers: GC03M125116 GC03M121005


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CCDC14 Gene:
CCDC14 (coiled-coil domain containing 14) is a protein-coding gene. Diseases associated with CCDC14 include schizophrenia, and ataxia.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC14 gene promoter:
         Sox5   MAZR   FOXJ2 (long isoform)   FOXO4   IRF-7A   Cart-1   c-Myb   FOXJ2   TGIF   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC14 promoter sequence
   Search Chromatin IP Primers for CCDC14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21.1   Ensembl cytogenetic band:  3q21.1   HGNC cytogenetic band: 3q21.1

CCDC14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC14 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M123616:  view genomic region     (about GC identifiers)

Start:
123,616,152 bp from pter      End:
123,680,564 bp from pter
Size:
64,413 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CCD14_HUMAN, Q49A88 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 14  
Size: 953 amino acids; 106302 Da
Sequence caution: Sequence=BAB14329.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB55229.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B7Z2T2 B8ZZ41 B8ZZ58 D3DN98 Q7Z3N3 Q86T30 Q8IWF8 Q8WUJ8 Q96K47 Q9H9A3
Q9UFH0
Alternative splicing: 6 isoforms:  Q49A88-1   Q49A88-2   Q49A88-3   Q49A88-4   Q49A88-5   Q49A88-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CCDC14: NX_Q49A88

Explore proteomics data for CCDC14 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys291, Lys389, Lys551, Lys606, Lys649, Lys821
  • Modification sites at PhosphoSitePlus

  • See CCDC14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_073594.4  
    ENSEMBL proteins: 
     ENSP00000420768   ENSP00000418002   ENSP00000386481   ENSP00000418403   ENSP00000395706  
     ENSP00000386866   ENSP00000400957   ENSP00000414655   ENSP00000407820   ENSP00000387962  
     ENSP00000398148   ENSP00000420180   ENSP00000312031  

    CCDC14 Human Recombinant Protein Products:

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    Abcam antibodies for CCDC14
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    Cloud-Clone Corp. CLIAs for CCDC14


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q49A88


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         3 GenomeRNAi human phenotypes for CCDC14:
     Increased G1 DNA content  Increased homologous recombina  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC14
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC14

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC14
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC14

    miRNA
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    miRTarBase miRNAs that target CCDC14:
    hsa-mir-29a-3p (MIRT049966), hsa-mir-215-5p (MIRT024890), hsa-mir-192-5p (MIRT026679), hsa-mir-21-5p (MIRT030992)

    Block miRNA regulation of human, mouse, rat CCDC14 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate CCDC14:
    hsa-miR-4314 hsa-miR-548t hsa-miR-1265 hsa-miR-3168 hsa-miR-622 hsa-miR-186 hsa-miR-3133 hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidCCDC14 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CCDC14
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC14

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for CCDC14
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    GenScript: all cDNA clones in your preferred vector: CCDC14 (NM_014695)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC14

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC14 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005813centrosome IDA--

    CCDC14 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC14
    Interactions:

        Search GeneGlobe Interaction Network for CCDC14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for CCDC14 (Q49A882, 3 ENSP000003868664) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2876033 I2D: score=3 STRING: ENSP00000357292
    MAGEA11P433642, 3, ENSP000003473584MINT-68001 I2D: score=5 STRING: ENSP00000347358
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0021762substantia nigra development IEP--

    CCDC14 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC14 (CCD14)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CCDC14 gene: 
    NM_022757.4  

    Unigene Cluster for CCDC14:

    Coiled-coil domain containing 14
    Hs.645028  [show with all ESTs]
    Unigene Representative Sequence: BX537652
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22):
    ENST00000463996 ENST00000479903 ENST00000485727 ENST00000409657 ENST00000495381(uc003egz.2)
    ENST00000489746(uc003egx.4) ENST00000433542 ENST00000409697 ENST00000483247
    ENST00000419247 ENST00000487498 ENST00000485949 ENST00000471054 ENST00000426152
    ENST00000435910 ENST00000434954 ENST00000477268 ENST00000438440
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCDC14 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate CCDC14:
    hsa-miR-4314 hsa-miR-548t hsa-miR-1265 hsa-miR-3168 hsa-miR-622 hsa-miR-186 hsa-miR-3133 hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidCCDC14 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CCDC14
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC14
    Clone
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    OriGene clones in human, mouse for CCDC14 (see all 8)
    OriGene ORF clones in mouse, rat for CCDC14
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC14 (NM_014695)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC14
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CCDC14
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC14
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC14
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC14
      QuantiFast Probe-based Assays in human, mouse, rat CCDC14

    Additional mRNA sequence: 

    AF086562.1 AK022954.1 AK027607.1 AK294979.1 AK295091.1 AK307847.1 AL122079.1 BC020246.1 
    BC040285.1 BC042613.1 BX537652.1 

    23 DOTS entries:

    DT.441721  DT.91954522  DT.95297940  DT.102829377  DT.206060  DT.120877591  DT.40244105  DT.100831983 
    DT.120877559  DT.100767737  DT.120877580  DT.120877601  DT.92431157  DT.120877565  DT.40114236  DT.102829374 
    DT.121632770  DT.91981232  DT.120877581  DT.91747804  DT.92431152  DT.92431154  DT.91942382 

    Selected AceView cDNA sequences (see all 222):

    CF528702 AI363747 AI379620 AW849835 AI681937 AA670363 BU145482 AA743453 
    BM504269 AW768969 R02119 BE218504 AW849734 AA761473 AI696528 AW023987 
    BQ002710 AW849781 BU626145 AW085976 AA449616 AA828514 AA830616 AI580087 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CCDC14 (see all 21)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e ·
    SP1:                                      -     -     -                             -     -     -     -                                                         
    SP2:                                      -                                         -     -     -     -                                                         
    SP3:                                                                                      -     -     -                                                         
    SP4:                                                                                -     -     -     -                                                         
    SP5:                                                                                -     -     -     -                                   -     -     -     -   

    ExUns: 10f ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15a · 15b ^ 16a · 16b ^ 17a · 17b · 17c
    SP1:                                                  -                                 
    SP2:                                                  -     -     -                     
    SP3:                                                  -                                 
    SP4:                                                  -                                 
    SP5:  -     -                                         -                                 


    ECgene alternative splicing isoforms for CCDC14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCDC14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAGCAGCAC
    CCDC14 Expression
    About this image

    CCDC14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.645028
        Custom PCR Arrays for CCDC14
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    QuantiFast Probe-based Assays in human, mouse, rat CCDC14
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CCDC14 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc141 , 5 coiled-coil domain containing 141, 5 76.96(n)1
    66.44(a)1
      16 (24.46 cM)5
    2398391  NM_172824.31  NP_766412.21 
     346906165 
    chicken
    (Gallus gallus)
    Aves CCDC141 coiled-coil domain containing 14 57.38(n)
    45.45(a)
      424252  XM_004942932.1  XP_004942989.1 
    lizard
    (Anolis carolinensis)
    Reptilia CCDC146
    coiled-coil domain containing 14
    36(a)
    1 ↔ 1
    1(78925756-78946106)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.142902 Xenopus laevis transcribed sequence with weak similarity more 75(n)    BM191834.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ccdc146
    coiled-coil domain containing 14
    22(a)
    1 ↔ 1
    6(8444747-8542728) ENSDARG00000086557


    ENSEMBL Gene Tree for CCDC14 (if available)
    TreeFam Gene Tree for CCDC14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CCDC14 gene

    CCDC14 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CCDC14
    PGOHUM00000257070


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCDC14 (see all 946)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs105737181,2
    C--121024283(+) TTCTT-/A/AA  
            
    AAAAA
    1 -- int10--------
    rs763313111,2
    C,F--123631772(+) TAATAT/CACCAA 1 -- ds50011Minor allele frequency- C:0.03NA 120
    rs608098031,2
    C,F--123631818(+) TTCTAA/CGGGGG 1 -- ds50013Minor allele frequency- C:0.07WA 122
    rs37324841,2
    C,F,A,H--123631829(-) CTTAAA/GTGTTT 1 -- ds500115Minor allele frequency- G:0.22NS EA NA WA 2044
    rs22505071,2
    C,F,H--123631836(-) GAACAG/ACCTTA 1 -- ds50017Minor allele frequency- A:0.26NS NA WA EA 484
    rs562015221,2
    C,F--123632005(+) TTGCAT/CGTTCC 1 -- ds50012Minor allele frequency- C:0.06WA 120
    rs1826647461,2
    --123632023(+) AGTCAC/TGTGCA 1 -- ds50010--------
    rs76443201,2
    C,F,H--123632027(+) ATGTGC/AATGTC 1 -- ds50015Minor allele frequency- A:0.05NS EA WA 538
    rs76119601,2
    C,F,H--123632122(+) ATTAAT/CTGAAC 1 -- ds500110Minor allele frequency- C:0.06NS EA NA WA 1212
    rs1869975091,2
    --123632135(+) ACAAGC/GGTTTA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for CCDC14 (123616152 - 123680564 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for CCDC14:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2725844CNV Deletion23290073
    esv2725843CNV Deletion23290073
    esv2725842CNV Deletion23290073
    esv2725845CNV Deletion23290073
    esv5313CNV Deletion18987735
    nsv520308CNV Gain19592680
    nsv877397CNV Gain21882294
    nsv460837CNV Gain19166990

    Human Gene Mutation Database (HGMD): CCDC14
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC14
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC14

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for CCDC14:    
    About MalaCards
    schizophrenia    ataxia


    CCDC14 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CCDC14

    Export disorders for CCDC14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCDC14 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with CCDC14)
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    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication. (PubMed id 24613305)1 Firat-Karalar E.N....Stearns T. (Curr. Biol. 2014)
    4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    7. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64770 HGNC: 25766 AceView: FLJ12892 Ensembl:ENSG00000175455 euGenes: HUgn64770
    ECgene: CCDC14 H-InvDB: CCDC14

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CCDC14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCDC14 gene:
    Search GeneIP for patents involving CCDC14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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