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Aliases for CCDC14 Gene

Aliases for CCDC14 Gene

  • Coiled-Coil Domain Containing 14 2 3

External Ids for CCDC14 Gene

Previous GeneCards Identifiers for CCDC14 Gene

  • GC03M125116
  • GC03M123616
  • GC03M121005

Summaries for CCDC14 Gene

GeneCards Summary for CCDC14 Gene

CCDC14 (Coiled-Coil Domain Containing 14) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC14 Gene

Genomics for CCDC14 Gene

Regulatory Elements for CCDC14 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC14 Gene

Start:
123,897,305 bp from pter
End:
123,961,408 bp from pter
Size:
64,104 bases
Orientation:
Minus strand

Genomic View for CCDC14 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC14 Gene

Proteins for CCDC14 Gene

  • Protein details for CCDC14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q49A88-CCD14_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 14
    Protein Accession:
    Q49A88
    Secondary Accessions:
    • B7Z2T2
    • B8ZZ41
    • B8ZZ58
    • D3DN98
    • Q7Z3N3
    • Q86T30
    • Q8IWF8
    • Q8WUJ8
    • Q96K47
    • Q9H9A3
    • Q9UFH0

    Protein attributes for CCDC14 Gene

    Size:
    953 amino acids
    Molecular mass:
    106302 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14329.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB55229.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC14 Gene

neXtProt entry for CCDC14 Gene

Proteomics data for CCDC14 Gene at MOPED

Post-translational modifications for CCDC14 Gene

  • Ubiquitination at Lys291, Lys389, Lys551, Lys606, Lys649, and Lys821
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CCDC14 Gene

Domains for CCDC14 Gene

Protein Domains for CCDC14 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC14 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC14: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC14 Gene

Function for CCDC14 Gene

Gene Ontology (GO) - Molecular Function for CCDC14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC14: view

Phenotypes for CCDC14 Gene

genes like me logo Genes that share phenotypes with CCDC14: view

Animal Model Products

miRNA for CCDC14 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC14 Gene

Localization for CCDC14 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC14 Gene COMPARTMENTS Subcellular localization image for CCDC14 gene
Compartment Confidence
cytoskeleton 5
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for CCDC14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005813 centrosome IDA 21399614
genes like me logo Genes that share ontologies with CCDC14: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC14 Gene

Pathways for CCDC14 Gene

SuperPathways for CCDC14 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0021762 substantia nigra development IEP 22926577
genes like me logo Genes that share ontologies with CCDC14: view

No data available for Pathways by source for CCDC14 Gene

Transcripts for CCDC14 Gene

Unigene Clusters for CCDC14 Gene

Coiled-coil domain containing 14:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC14

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC14 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e ·
SP1: - - - - - - -
SP2: - - - - -
SP3: - - -
SP4: - - - -
SP5: - - - - - - - -
SP6: - - - - -
SP7: - - - -
SP8: - - - -
SP9: - - - - - - - - -
SP10: - - - - - - -
SP11: - - - - - - - - -
SP12: -
SP13:
SP14: - - - - - - - - - - -
SP15: - - - - - - - -
SP16: - - - - - - - - - -
SP17: - - - - - - - - -
SP18:
SP19: -
SP20: - - - - - - - - - - - - - - - - - - - -
SP21:

ExUns: 10f ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15a · 15b ^ 16a · 16b ^ 17a · 17b · 17c
SP1: -
SP2: - - -
SP3: -
SP4: -
SP5: - - -
SP6:
SP7:
SP8: - - - -
SP9:
SP10:
SP11:
SP12:
SP13: -
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20: - - - - - - - - - -
SP21:

Relevant External Links for CCDC14 Gene

GeneLoc Exon Structure for
CCDC14
ECgene alternative splicing isoforms for
CCDC14

Expression for CCDC14 Gene

mRNA expression in normal human tissues for CCDC14 Gene

Protein differential expression in normal tissues for CCDC14 Gene

This gene is overexpressed in Colon muscle (49.3) and Heart (11.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC14 Gene

SOURCE GeneReport for Unigene cluster for CCDC14 Gene Hs.645028

genes like me logo Genes that share expressions with CCDC14: view

Expression partners for CCDC14 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC14 Gene

Orthologs for CCDC14 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC14 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CCDC14 35
  • 84.45 (n)
  • 75.39 (a)
CCDC14 36
  • 72 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC14 35
  • 84.97 (n)
  • 77.45 (a)
CCDC14 36
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc14 35
  • 76.96 (n)
  • 66.44 (a)
Ccdc14 16
Ccdc14 36
  • 63 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CCDC14 35
  • 99.12 (n)
  • 98.46 (a)
CCDC14 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc14 35
  • 75.08 (n)
  • 64.19 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 46 (a)
OneToMany
-- 36
  • 33 (a)
OneToMany
chicken
(Gallus gallus)
Aves CCDC14 35
  • 57.38 (n)
  • 45.45 (a)
CCDC14 36
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC14 36
  • 36 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491976 35
  • 50.42 (n)
  • 43.56 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.14290 35
zebrafish
(Danio rerio)
Actinopterygii ccdc14 36
  • 22 (a)
OneToOne
Species with no ortholog for CCDC14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC14 Gene

ENSEMBL:
Gene Tree for CCDC14 (if available)
TreeFam:
Gene Tree for CCDC14 (if available)

Paralogs for CCDC14 Gene

Pseudogenes.org Pseudogenes for CCDC14 Gene

genes like me logo Genes that share paralogs with CCDC14: view

No data available for Paralogs for CCDC14 Gene

Variants for CCDC14 Gene

Sequence variations from dbSNP and Humsavar for CCDC14 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1064236 -- 123,947,126(-) AGGAA(C/T)TCATA missense, reference, intron-variant
rs1814975 -- 123,959,722(+) TGGTA(C/T)GTGGA intron-variant
rs1879362 -- 123,946,601(+) TTTGA(C/T)ATTCT intron-variant
rs1920214 -- 123,897,285(+) TTTGA(C/T)TGAGA downstream-variant-500B
rs1920215 -- 123,902,329(+) CTGCA(A/G)TCCTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC14 Gene

Variant ID Type Subtype PubMed ID
nsv460837 CNV Gain 19166990
nsv520308 CNV Gain 19592680
nsv877397 CNV Gain 21882294
esv2725842 CNV Deletion 23290073
esv5313 CNV Deletion 18987735
esv2725843 CNV Deletion 23290073
esv2725844 CNV Deletion 23290073
esv2725845 CNV Deletion 23290073

Relevant External Links for CCDC14 Gene

HapMap Linkage Disequilibrium report
CCDC14
Human Gene Mutation Database (HGMD)
CCDC14

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC14 Gene

Disorders for CCDC14 Gene

Relevant External Links for CCDC14

Genetic Association Database (GAD)
CCDC14

No disorders were found for CCDC14 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CCDC14 Gene

Publications for CCDC14 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  5. Scanning the human proteome for calmodulin-binding proteins. (PMID: 15840729) Shen X. … Liu R. (Proc. Natl. Acad. Sci. U.S.A. 2005) 3

Products for CCDC14 Gene

Sources for CCDC14 Gene

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