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Aliases for CCDC138 Gene

Aliases for CCDC138 Gene

  • Coiled-Coil Domain Containing 138 2 3

External Ids for CCDC138 Gene

Previous GeneCards Identifiers for CCDC138 Gene

  • GC02P109403
  • GC02P103001

Summaries for CCDC138 Gene

GeneCards Summary for CCDC138 Gene

CCDC138 (Coiled-Coil Domain Containing 138) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC138 Gene

Genomics for CCDC138 Gene

Regulatory Elements for CCDC138 Gene

Genomic Location for CCDC138 Gene

Start:
108,786,752 bp from pter
End:
108,885,477 bp from pter
Size:
98,726 bases
Orientation:
Plus strand

Genomic View for CCDC138 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC138 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC138 Gene

Proteins for CCDC138 Gene

  • Protein details for CCDC138 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96M89-CC138_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 138
    Protein Accession:
    Q96M89
    Secondary Accessions:
    • Q05DF1
    • Q4ZG07
    • Q53TE1
    • Q6ZUY5
    • Q86VL7

    Protein attributes for CCDC138 Gene

    Size:
    665 amino acids
    Molecular mass:
    76219 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC138 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC138 Gene

Proteomics data for CCDC138 Gene at MOPED

Post-translational modifications for CCDC138 Gene

  • Ubiquitination at Lys19, Lys41, Lys157, Lys200, Lys230, Lys295, Lys313, Lys399, and Lys463
  • Modification sites at PhosphoSitePlus

Other Protein References for CCDC138 Gene

No data available for DME Specific Peptides for CCDC138 Gene

Domains for CCDC138 Gene

Protein Domains for CCDC138 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC138 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC138: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC138 Gene

Function for CCDC138 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC138

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC138 Gene

Localization for CCDC138 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC138 Gene COMPARTMENTS Subcellular localization image for CCDC138 gene
Compartment Confidence
cytosol 3
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC138 Gene

Pathways for CCDC138 Gene

SuperPathways for CCDC138 Gene

No Data Available

Interacting Proteins for CCDC138 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000295124%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000324729%0d%0a
Selected Interacting proteins: ENSP00000295124 for CCDC138 Gene via STRING

Gene Ontology (GO) - Biological Process for CCDC138 Gene

None

No data available for Pathways by source for CCDC138 Gene

Transcripts for CCDC138 Gene

Unigene Clusters for CCDC138 Gene

Coiled-coil domain containing 138:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC138

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CCDC138

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC138 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c · 15d
SP1: -
SP2: -
SP3: - -
SP4: -
SP5: - -

Relevant External Links for CCDC138 Gene

GeneLoc Exon Structure for
CCDC138
ECgene alternative splicing isoforms for
CCDC138

Expression for CCDC138 Gene

mRNA expression in normal human tissues for CCDC138 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC138 Gene

This gene is overexpressed in Testis (5.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC138 Gene

SOURCE GeneReport for Unigene cluster for CCDC138 Gene Hs.731709

genes like me logo Genes that share expressions with CCDC138: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCDC138 Gene

Orthologs for CCDC138 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC138 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC138 35
  • 99.45 (n)
  • 99.1 (a)
CCDC138 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC138 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC138 35
  • 88.35 (n)
  • 86.9 (a)
CCDC138 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc138 35
  • 81.67 (n)
  • 79.31 (a)
Ccdc138 16
Ccdc138 36
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC138 36
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC138 36
  • 61 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc138 35
  • 82.9 (n)
  • 81.54 (a)
lizard
(Anolis carolinensis)
Reptilia CCDC138 36
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc138 35
  • 64.07 (n)
  • 56.06 (a)
Str.4317 35
zebrafish
(Danio rerio)
Actinopterygii CCDC138 36
  • 42 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2655 36
  • 37 (a)
OneToOne
Species with no ortholog for CCDC138:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC138 Gene

ENSEMBL:
Gene Tree for CCDC138 (if available)
TreeFam:
Gene Tree for CCDC138 (if available)

Paralogs for CCDC138 Gene

No data available for Paralogs for CCDC138 Gene

Variants for CCDC138 Gene

Sequence variations from dbSNP and Humsavar for CCDC138 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs14402 -- 108,876,451(-) TAGTA(C/T)TACCT downstream-variant-500B, utr-variant-3-prime
rs826550 -- 108,791,042(-) gctca(C/T)gcctg intron-variant
rs826551 -- 108,790,913(-) ttagc(C/T)gggag intron-variant
rs826552 -- 108,789,330(-) caggc(A/G)tgagc intron-variant
rs826553 -- 108,786,656(-) TTGTC(A/G)GCGCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CCDC138 Gene

Variant ID Type Subtype PubMed ID
nsv2872 CNV Insertion 18451855

Relevant External Links for CCDC138 Gene

HapMap Linkage Disequilibrium report
CCDC138

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC138 Gene

Disorders for CCDC138 Gene

No disorders were found for CCDC138 Gene.

No data available for UniProtKB/Swiss-Prot for CCDC138 Gene

Publications for CCDC138 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PMID: 17203973) Vasilescu J. … Figeys D. (J. Proteome Res. 2007) 3 4
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for CCDC138 Gene

Sources for CCDC138 Gene

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