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CCDC136 Gene

protein-coding   GIFtS: 51
GCID: GC07P128430

Coiled-Coil Domain Containing 136

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Coiled-Coil Domain Containing 1361 2
Nasopharyngeal Carcinoma-Associated Gene 6 Protein2 3
KIAA17933 5
Coiled-Coil Domain-Containing Protein 1362
NAG65

External Ids:    HGNC: 222251   Entrez Gene: 647532   Ensembl: ENSG000001285967   OMIM: 6119025   UniProtKB: Q96JN23   
ORGUL members:         

Export aliases for CCDC136 gene to outside databases

Previous GC identifers: GC07P128219 GC07P122792


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CCDC136 Gene:
CCDC136 (coiled-coil domain containing 136) is a protein-coding gene. Diseases associated with CCDC136 include nasopharyngitis, and schizophrenia. An important paralog of this gene is TRAF3IP3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC136 gene promoter:
         E2F-4   E2F-3a   E2F-5   AP-1   ATF-2   E2F-2   E2F   E2F-1   USF-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): CCDC136 promoter sequence
   Search Chromatin IP Primers for CCDC136

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC136


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q33   Ensembl cytogenetic band:  7q32.1   HGNC cytogenetic band: 7q33

CCDC136 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC136 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P128430:  view genomic region     (about GC identifiers)

Start:
128,430,811 bp from pter      End:
128,462,187 bp from pter
Size:
31,377 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 127,814,448-127,845,932     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CC136_HUMAN, Q96JN2 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 136  
Size: 1154 amino acids; 134045 Da
Miscellaneous: Restriction fragment length polymorphisms (RFLPs) in gastric cancer showed loss of 5 kb fragment in
comparison with the corresponding normal tissue
Sequence caution: Sequence=AF156971; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=BAB14590.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB47422.1; Type=Erroneous
initiation; Note=Translation N-terminally shortened;
Secondary accessions: A4D1K1 A7MCY7 A8MYA7 Q6ZVK7 Q9H8M3 Q9UFE1
Alternative splicing: 4 isoforms:  Q96JN2-1   Q96JN2-2   Q96JN2-3   Q96JN2-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CCDC136: NX_Q96JN2

Explore proteomics data for CCDC136 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CCDC136 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001188301.1  NP_073579.4  

    ENSEMBL proteins: 
     ENSP00000418838   ENSP00000417708   ENSP00000367956   ENSP00000419515   ENSP00000417209  
     ENSP00000418042   ENSP00000420509   ENSP00000297788   ENSP00000417931   ENSP00000417991  

    CCDC136 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CCDC136

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    Abcam antibodies for CCDC136
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    Cloud-Clone Corp. ELISAs for CCDC136
    Cloud-Clone Corp. CLIAs for CCDC136


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q96JN2


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC136
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC136

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC136
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC136

    miRNA
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    miRTarBase miRNAs that target CCDC136:
    hsa-mir-484 (MIRT041851)

    Block miRNA regulation of human, mouse, rat CCDC136 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate CCDC136:
    hsa-miR-370 hsa-miR-2115 hsa-miR-555 hsa-miR-1827 hsa-miR-3145-3p hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidCCDC136 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CCDC136

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    GenScript: all cDNA clones in your preferred vector (see all 2): CCDC136 (NM_022742)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC136
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC136

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC136


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CC136_HUMAN, Q96JN2: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    nucleus2
    cytosol1
    endoplasmic reticulum1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0016021integral component of membrane IEA--

    CCDC136 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC136
    Interactions:

        Search GeneGlobe Interaction Network for CCDC136

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for CCDC136 (Q96JN22, 3 ENSP000002977884) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PKN2Q165132, 3, ENSP000003595524MINT-8266656 I2D: score=2 STRING: ENSP00000359552
    DISC1Q9NRI53, ENSP000003555964I2D: score=2 STRING: ENSP00000355596
    ATXN1P542533, ENSP000002447694I2D: score=1 STRING: ENSP00000244769
    COILP384323, ENSP000002403164I2D: score=1 STRING: ENSP00000240316
    GFI1BQ5VTD93, ENSP000003447824I2D: score=1 STRING: ENSP00000344782
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC136 (CC136)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CCDC136 gene (2 alternative transcripts): 
    NM_001201372.1  NM_022742.4  

    Unigene Cluster for CCDC136:

    Coiled-coil domain containing 136
    Hs.521178  [show with all ESTs]
    Unigene Representative Sequence: NM_022742
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485998 ENST00000459946 ENST00000378685(uc003vnu.2) ENST00000464832
    ENST00000472049 ENST00000488925 ENST00000487361 ENST00000297788(uc003vnv.2)
    ENST00000480137(uc003vnx.2 uc010llq.2 uc003vny.2) ENST00000494552
    ENST00000528772 ENST00000464672 ENST00000485832 ENST00000460941 ENST00000471729

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCDC136 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate CCDC136:
    hsa-miR-370 hsa-miR-2115 hsa-miR-555 hsa-miR-1827 hsa-miR-3145-3p hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidCCDC136 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CCDC136
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC136
    Clone
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    OriGene clones in human, mouse for CCDC136 (see all 6)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CCDC136 (NM_022742)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC136
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC136
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC136
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC136
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC136
      QuantiFast Probe-based Assays in human, mouse, rat CCDC136

    Additional mRNA sequence: 

    AB058696.1 AK023500.1 AK124447.1 AL133027.1 BC150331.1 BC152408.1 

    15 DOTS entries:

    DT.97814867  DT.99954759  DT.40211437  DT.97803614  DT.121071031  DT.95228950  DT.444765  DT.121070983 
    DT.121071022  DT.40239454  DT.444764  DT.95087487  DT.95161506  DT.97773734  DT.121003113 

    Selected AceView cDNA sequences (see all 88):

    AB058696 NM_022742 AI498231 AK124447 BM930706 AA077347 BQ009656 AL044719 
    AL133027 BU194825 AI032374 AL042602 BG721616 AA301612 AI580749 CR595997 
    AI918726 CD557153 T33167 BM711653 AI025327 AA781750 AI350548 BX952188 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CCDC136 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c · 12d ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a ·
    SP1:                                                                          -     -                                                                           
    SP2:                          -                       -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -               
    SP3:                                                                          -     -                                                     -     -     -         
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 17b
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for CCDC136

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCDC136 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTCCCCATC
    CCDC136 Expression
    About this image

    CCDC136 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC136 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.521178

    UniProtKB/Swiss-Prot: CC136_HUMAN, Q96JN2
    Tissue specificity: Expressed in gastric tissues. Down-regulated in gastric cancer

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC136

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CCDC136 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc1361 , 5 coiled-coil domain containing 1361, 5 80.79(n)1
    73.66(a)1
      6 (12.36 cM)5
    2326641  NM_145574.31  NP_663549.31 
     293963095 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ccdc1361 coiled-coil domain containing 136 57.9(n)
    50.32(a)
      100216100  NM_001199921.1  NP_001186850.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003301861 coiled-coil domain-containing protein 136-like 56.68(n)
    48.93(a)
      100330186  XM_005164607.1  XP_005164664.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG174946
    --
    7(a)
    1 → many
    2L(22471804-22478575)
    worm
    (Caenorhabditis elegans)
    Secernentea M4.16
    Protein M4.1 (M4.1) mRNA, complete cds
    10(a)
    1 → many
    IV(3213772-3219513) WBGene00019766


    ENSEMBL Gene Tree for CCDC136 (if available)
    TreeFam Gene Tree for CCDC136 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CCDC136 gene
    TRAF3IP32  SLMAP2  
    1 SIMAP similar gene for CCDC136 using alignment to 8 protein entries:     CC136_HUMAN (see all proteins):
    SLMAP

    CCDC136 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCDC136 (see all 673)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1416143021,2
    C--128429594(+) GATTG-/AC    
       CTTTA
    ACTCA
    1 -- us2k10--------
    rs782363281,2
    C,F--128429663(+) GATCCC/TCCTAA 1 -- us2k11Minor allele frequency- T:0.05WA 118
    rs1473820581,2
    --128429735(+) AGGGGC/TGAGCA 1 -- us2k10--------
    rs1395901321,2
    --128429977(+) ATTCCC/TAGACG 1 -- us2k10--------
    rs1119412551,2
    C--128438411(+) AGCAATTC/-TTCTG 1 -- int11Minor allele frequency- -:0.50CSA 2
    rs47281371,2,,4
    C,F,H--128455767(+) AAAAGG/CAAGTG 1 -- int115Minor allele frequency- C:0.01NS EA NA WA CSA 618
    rs1432085721,2
    --131773783(+) ACTTTC/GCTAAT 1 -- us2k10--------
    rs791360571,2
    C,F--131773832(+) TCTTTC/ATTGCG 1 -- us2k11Minor allele frequency- A:0.03EA 120
    rs608713861,2
    C,F--131773891(+) GCAGCG/TGGGGG 1 -- us2k18Minor allele frequency- T:0.14WA NA CSA EA 368
    rs1475216191,2
    --131773944(+) AGAGAC/GGGGAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCDC136 (128430811 - 128462187 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CCDC136 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2735137CNV Deletion23290073
    esv2670312CNV Deletion23128226
    esv2642516CNV Insertion19546169
    nsv512922CNV Insertion21212237
    esv1249692CNV Insertion17803354
    nsv464715CNV Loss19166990
    nsv819324CNV Loss19587683
    nsv464713CNV Loss19166990
    nsv831125CNV Loss17160897
    dgv7490n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC136
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC136

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611902    OMIM disorders: --

    3 diseases for CCDC136:    
    About MalaCards
    nasopharyngitis    schizophrenia    ataxia


    CCDC136 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CCDC136
    Human Genome Epidemiology (HuGE) Navigator: CCDC136 (1 document)

    Export disorders for CCDC136 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCDC136 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with CCDC136)
        Utopia: connect your pdf to the dynamic
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    1. Expression of tumor related gene NAG6 in gastric cancer and restriction fragment length polymorphism analysis. (PubMed id 15112360)1, 2, 3, 9 Zhang X.-M.... Li G.-Y. (World J. Gastroenterol. 2004)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    5. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    6. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    7. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)1 Camargo L.M....Brandon N.J. (Mol. Psychiatry 2007)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (Cell 2006)
    10. A protein interaction framework for human mRNA degradation. (PubMed id 15231747)1 Lehner B. and Sanderson C.M. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Free Text  

      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64753 HGNC: 22225 AceView: DKFZP434G156 Ensembl:ENSG00000128596 euGenes: HUgn64753
    ECgene: CCDC136 H-InvDB: CCDC136

    (According to HUGE)
    About This Section

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    HUGE: KIAA1793

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CCDC136 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCDC136 gene:
    Search GeneIP for patents involving CCDC136

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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