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Aliases for CCDC132 Gene

Aliases for CCDC132 Gene

  • Coiled-Coil Domain Containing 132 2 3
  • KIAA1861 4

External Ids for CCDC132 Gene

Summaries for CCDC132 Gene

GeneCards Summary for CCDC132 Gene

CCDC132 (Coiled-Coil Domain Containing 132) is a Protein Coding gene.

Gene Wiki entry for CCDC132 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC132 Gene

Genomics for CCDC132 Gene

Genomic Location for CCDC132 Gene

Start:
93,232,340 bp from pter
End:
93,361,123 bp from pter
Size:
128,784 bases
Orientation:
Plus strand

Genomic View for CCDC132 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC132 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC132 Gene

Regulatory Elements for CCDC132 Gene

Proteins for CCDC132 Gene

  • Protein details for CCDC132 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96JG6-CC132_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 132
    Protein Accession:
    Q96JG6
    Secondary Accessions:
    • B3KX22
    • D1MQ00
    • F5H5U7
    • Q75N07
    • Q8WVK3
    • Q9H5C6

    Protein attributes for CCDC132 Gene

    Size:
    964 amino acids
    Molecular mass:
    111174 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15701.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB47490.2; Type=Frameshift; Positions=2; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC132 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC132 Gene

Proteomics data for CCDC132 Gene at MOPED

Post-translational modifications for CCDC132 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC132 Gene

Domains for CCDC132 Gene

Protein Domains for CCDC132 Gene

genes like me logo Genes that share domains with CCDC132: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC132 Gene

Function for CCDC132 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC132 Gene

Localization for CCDC132 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC132 Gene COMPARTMENTS Subcellular localization image for CCDC132 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for CCDC132 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IDA 19946888
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with CCDC132: view

Pathways for CCDC132 Gene

SuperPathways for CCDC132 Gene

No Data Available

Interacting Proteins for CCDC132 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000307666%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000307666 for CCDC132 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CCDC132 Gene

None

No data available for Pathways by source for CCDC132 Gene

Transcripts for CCDC132 Gene

Unigene Clusters for CCDC132 Gene

Coiled-coil domain containing 132:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC132 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^
SP1: - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - -
SP5: -
SP6:
SP7:
SP8:

ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32
SP1: - - -
SP2: - - -
SP3: - - - - -
SP4:
SP5:
SP6:
SP7:
SP8:

Relevant External Links for CCDC132 Gene

GeneLoc Exon Structure for
CCDC132
ECgene alternative splicing isoforms for
CCDC132

Expression for CCDC132 Gene

mRNA expression in normal human tissues for CCDC132 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC132 Gene

SOURCE GeneReport for Unigene cluster for CCDC132 Gene Hs.202424

mRNA Expression by UniProt/SwissProt for CCDC132 Gene

Q96JG6-CC132_HUMAN
Tissue specificity: Ubiquitous, with higher expression in brain and skeletal muscle.
genes like me logo Genes that share expressions with CCDC132: view

Orthologs for CCDC132 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CCDC132 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC132 36
  • 99.65 (n)
  • 99.59 (a)
CCDC132 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC132 36
  • 93.19 (n)
  • 97.72 (a)
CCDC132 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC132 36
  • 93.6 (n)
  • 98.96 (a)
CCDC132 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc132 36
  • 89.56 (n)
  • 96.27 (a)
Ccdc132 16
Ccdc132 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC132 37
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC132 37
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc132 36
  • 89.94 (n)
  • 96.37 (a)
chicken
(Gallus gallus)
Aves CCDC132 36
  • 81.96 (n)
  • 91.44 (a)
CCDC132 37
  • 91 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC132 37
  • 91 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc132 36
  • 77.8 (n)
  • 87.97 (a)
zebrafish
(Danio rerio)
Actinopterygii CCDC132 (1 of 2) 37
  • 84 (a)
OneToMany
CCDC132 (2 of 2) 37
  • 87 (a)
OneToMany
si:ch211-287b5.1 36
  • 71.38 (n)
  • 83.97 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000343 36
  • 42.89 (n)
  • 34.13 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4996 36
  • 47.08 (n)
  • 36.08 (a)
CG4996 37
  • 32 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea C44B9.1 36
  • 44.59 (n)
  • 32.23 (a)
vesa-1 37
  • 28 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G27900 36
  • 43.28 (n)
  • 29.83 (a)
rice
(Oryza sativa)
Liliopsida Os10g0546300 36
  • 41.87 (n)
  • 28.17 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 48 (a)
OneToOne
Species with no ortholog for CCDC132:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC132 Gene

ENSEMBL:
Gene Tree for CCDC132 (if available)
TreeFam:
Gene Tree for CCDC132 (if available)

Paralogs for CCDC132 Gene

genes like me logo Genes that share paralogs with CCDC132: view

No data available for Paralogs for CCDC132 Gene

Variants for CCDC132 Gene

Sequence variations from dbSNP and Humsavar for CCDC132 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs722263 -- 93,257,500(-) ATTGT(C/T)CAGCT intron-variant
rs725828 -- 93,269,771(+) TCTCA(A/G)AACTT intron-variant
rs763682 -- 93,265,101(-) GATTA(G/T)GAAAG intron-variant
rs881404 -- 93,233,440(-) CAACA(A/G)GAAAA intron-variant
rs1013642 -- 93,240,203(+) CAGTT(A/G)TATAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC132 Gene

Variant ID Type Subtype PubMed ID
nsv528267 CNV Loss 19592680
nsv888737 CNV Loss 21882294

Relevant External Links for CCDC132 Gene

HapMap Linkage Disequilibrium report
CCDC132

Disorders for CCDC132 Gene

Relevant External Links for CCDC132

Genetic Association Database (GAD)
CCDC132
Human Genome Epidemiology (HuGE) Navigator
CCDC132
genes like me logo Genes that share disorders with CCDC132: view

No data available for UniProtKB/Swiss-Prot for CCDC132 Gene

Publications for CCDC132 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49
  5. CCDC132 is highly expressed in atopic dermatitis T cells. (PMID: 21472204) Matsumoto Y. … Oshida T. (Mol. Med. Report. 2010) 3 4

Products for CCDC132 Gene

Sources for CCDC132 Gene

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