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Aliases for CCDC130 Gene

Aliases for CCDC130 Gene

  • Coiled-Coil Domain Containing 130 2 3
  • 9 KDa Protein 4

External Ids for CCDC130 Gene

Previous GeneCards Identifiers for CCDC130 Gene

  • GC19P013860
  • GC19P013430

Summaries for CCDC130 Gene

GeneCards Summary for CCDC130 Gene

CCDC130 (Coiled-Coil Domain Containing 130) is a Protein Coding gene. Diseases associated with CCDC130 include phlebotomus fever and trench fever. An important paralog of this gene is CCDC94.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC130 Gene

Genomics for CCDC130 Gene

Regulatory Elements for CCDC130 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC130 Gene

Start:
13,731,760 bp from pter
End:
13,763,296 bp from pter
Size:
31,537 bases
Orientation:
Plus strand

Genomic View for CCDC130 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC130 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC130 Gene

Proteins for CCDC130 Gene

  • Protein details for CCDC130 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P13994-CC130_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 130
    Protein Accession:
    P13994
    Secondary Accessions:
    • Q9BQ72

    Protein attributes for CCDC130 Gene

    Size:
    396 amino acids
    Molecular mass:
    44802 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA32138.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAA32138.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305};

neXtProt entry for CCDC130 Gene

Proteomics data for CCDC130 Gene at MOPED

Post-translational modifications for CCDC130 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC130 Gene

No data available for DME Specific Peptides for CCDC130 Gene

Domains for CCDC130 Gene

Protein Domains for CCDC130 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC130 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P13994

UniProtKB/Swiss-Prot:

CC130_HUMAN :
  • P13994
Family:
  • Belongs to the CWC16 family.
genes like me logo Genes that share domains with CCDC130: view

No data available for Gene Families for CCDC130 Gene

Function for CCDC130 Gene

Molecular function for CCDC130 Gene

UniProtKB/Swiss-Prot Induction: By poly(RI), poly(RC) and Newcastle disease virus.

Gene Ontology (GO) - Molecular Function for CCDC130 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with CCDC130: view
genes like me logo Genes that share phenotypes with CCDC130: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC130

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC130 Gene

Localization for CCDC130 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC130 Gene COMPARTMENTS Subcellular localization image for CCDC130 gene
Compartment Confidence
nucleus 3
cytosol 2
chloroplast 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CCDC130 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with CCDC130: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC130 Gene

Pathways for CCDC130 Gene

SuperPathways for CCDC130 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC130 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009615 response to virus IEP 3203696
genes like me logo Genes that share ontologies with CCDC130: view

No data available for Pathways by source for CCDC130 Gene

Transcripts for CCDC130 Gene

Unigene Clusters for CCDC130 Gene

Coiled-coil domain containing 130:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC130

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC130 Gene

No ASD Table

Relevant External Links for CCDC130 Gene

GeneLoc Exon Structure for
CCDC130
ECgene alternative splicing isoforms for
CCDC130

Expression for CCDC130 Gene

mRNA expression in normal human tissues for CCDC130 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC130 Gene

SOURCE GeneReport for Unigene cluster for CCDC130 Gene Hs.24998

genes like me logo Genes that share expressions with CCDC130: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC130 Gene

Orthologs for CCDC130 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CCDC130 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC130 35
  • 99.66 (n)
  • 99.49 (a)
CCDC130 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC130 35
  • 87.37 (n)
  • 86.36 (a)
CCDC130 36
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC130 35
  • 86.7 (n)
  • 87.63 (a)
CCDC130 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc130 35
  • 76.58 (n)
  • 80.79 (a)
Ccdc130 16
Ccdc130 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC130 36
  • 76 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC130 36
  • 69 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc130 35
  • 78.18 (n)
  • 80.1 (a)
lizard
(Anolis carolinensis)
Reptilia CCDC130 36
  • 64 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.3673 35
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc130 35
  • 65.42 (n)
  • 68.45 (a)
zebrafish
(Danio rerio)
Actinopterygii ccdc130 35
  • 59.35 (n)
  • 60.58 (a)
ccdc130 36
  • 58 (a)
OneToOne
Dr.18993 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007890 35
  • 58.9 (n)
  • 52.43 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG15084 35
  • 57.79 (n)
  • 52.22 (a)
CG15084 36
  • 51 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea CELE_ZK1307.9 35
  • 51.82 (n)
  • 50.78 (a)
ZK1307.9 36
  • 39 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YJU2 36
  • 23 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G25682 35
  • 52.42 (n)
  • 48.55 (a)
barley
(Hordeum vulgare)
Liliopsida Hv.2132 35
rice
(Oryza sativa)
Liliopsida Os.10889 35
Os02g0324300 35
  • 52.25 (n)
  • 49.03 (a)
wheat
(Triticum aestivum)
Liliopsida Ta.5602 35
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.9438 35
Species with no ortholog for CCDC130:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for CCDC130 Gene

ENSEMBL:
Gene Tree for CCDC130 (if available)
TreeFam:
Gene Tree for CCDC130 (if available)

Paralogs for CCDC130 Gene

Paralogs for CCDC130 Gene

Selected SIMAP similar genes for CCDC130 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with CCDC130: view

Variants for CCDC130 Gene

Sequence variations from dbSNP and Humsavar for CCDC130 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs109083 -- 13,748,453(+) CAAGC(C/T)GTAAG intron-variant
rs346170 -- 13,731,846(-) CTCTT(A/G)GCCCC utr-variant-5-prime
rs346171 -- 13,732,188(-) TGGAC(A/C)TCAGT utr-variant-5-prime
rs346172 -- 13,732,419(-) TCGCC(A/G)TCACT intron-variant
rs346173 -- 13,733,459(-) caggc(A/G)tcagc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC130 Gene

Variant ID Type Subtype PubMed ID
esv34036 CNV Loss 18971310
nsv833756 CNV Loss 17160897
nsv833757 CNV Loss 17160897

Relevant External Links for CCDC130 Gene

HapMap Linkage Disequilibrium report
CCDC130

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC130 Gene

Disorders for CCDC130 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (2) Diseases for CCDC130 Gene including...

Search for CCDC130 Gene in MalaCards »

(2) University of Copenhagen DISEASES for CCDC130 Gene

genes like me logo Genes that share disorders with CCDC130: view

No data available for UniProtKB/Swiss-Prot for CCDC130 Gene

Publications for CCDC130 Gene

  1. Alternative mechanisms for gene activation induced by poly(rI).poly(rC) and Newcastle disease virus. (PMID: 3203696) Lammers R. … Collins J. (Eur. J. Biochem. 1988) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3

Products for CCDC130 Gene

Sources for CCDC130 Gene

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