CCDC129 Gene
protein-coding GIFtS: 38
GCID: GC07P031523
|
|
coiled-coil domain containing 129
| |
Aliases
for CCDC129 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 1291 2 | | FLJ383441 | | Coiled-Coil Domain-Containing Protein 1292 |
Export aliases for CCDC129 gene to outside databases |
Summaries
for CCDC129 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC129 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC129 gene promoter:
GCNF POU3F2 FOXL1 AREB6 SRY FOXO4 GCNF-1 Cart-1 GCNF-2 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC129
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC129 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p14.3 Ensembl cytogenetic band: 7p14.3 HGNC cytogenetic band: 7p14.3CCDC129 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P031523: view genomic region
(about GC identifiers)
Start:
|
31,553,704 bp from pter |
End:
|
31,698,334 bp from pter |
Size:
|
144,631 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 31,604,683-31,741,029 |
|
Proteins
for CCDC129 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC129_HUMAN, Q6ZRS4 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 129 Size: 1044 amino acids; 115403 Da
Sequence caution: Sequence=BAG65223.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A2RU17 B3KTI9 B4DHB0 B4E2R1 F5H3V5Alternative splicing: 4 isoforms: Q6ZRS4-1 Q6ZRS4-2 Q6ZRS4-3 Q6ZRS4-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CCDC129: NX_Q6ZRS4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZRS4
CCDC129 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001244896.1 NP_001244897.1 NP_919276.2
ENSEMBL proteins: ENSP00000387220 ENSP00000390544 ENSP00000313062 ENSP00000384416 ENSP00000413233 ENSP00000387214 ENSP00000395835
Human Recombinant Protein Products:
CCDC129 Antibody Products:
Assay Products for CCDC129: |
Protein
Domains /
Families
for CCDC129 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6ZRS4 |
Function
for CCDC129 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC129 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC129
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC129 (NM_194300) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC129 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC129 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC129 |
|
Pathways & Interactions
for CCDC129 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC129
|
Drugs & Compounds
for CCDC129 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC129
Search CenterWatch for drugs/clinical trials and news about CCDC129 / CC129
|
Transcripts
for CCDC129 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC129 gene (3 alternative transcripts): NM_001257967.1 NM_001257968.1 NM_194300.3 Unigene Cluster for CCDC129: Coiled-coil domain containing 129 Hs.224269 [show with all ESTs]Unigene Representative Sequence: AK12802610 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000409717 ENST00000456011 ENST00000319386(uc011kad.1 uc003tcj.1 uc003tci.1)
ENST00000407970 ENST00000482748 ENST00000454513 ENST00000409210(uc003tck.1)
ENST00000471139 ENST00000463693 ENST00000451887(uc011kae.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC129 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC129
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC129 (NM_194300) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC129 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC129 |
Additional cDNA sequence: AK095663.1 AK128026.1 AK295011.1 AK304387.1 BC132719.1 NR_047565.1 5 DOTS entries: DT.70103053 DT.101977386 DT.75110509 DT.99938300 DT.121116567 17 AceView cDNA sequences: BF477838 AK128026 BE218326 NM_194300 BE670564 BE328040 AW196690 AK095663 AI184130 BE504029 AW051699 AI688561 BE502832 AI948874 BE672879 AW236837 AI635741
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC129 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 |
|---|
|
| SP1: | | | - | | | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CCDC129
|
Expression
for CCDC129 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC129 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGGCTATTA
About this image
See CCDC129 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC129
SOURCE GeneReport for Unigene cluster: Hs.224269
SABiosciences Custom PCR Arrays for CCDC129
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC129
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCDC129 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC129 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC129 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC129 |
Orthologs
for CCDC129 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CCDC129 gene from 3/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
CCDC1296 |
-- |
35(a) |
1 ↔ 1 |
6(44643908-44664705) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.105802 |
Transcribed sequence with weak similarity to protein more |
76.19(n) |
|
137717263 |
zebrafish
(Danio rerio) |
Actinopterygii |
ccdc1296 |
coiled-coil domain containing 129 |
24(a) |
1 ↔ 1 |
24(33620073-33657785) |
ENSEMBL Gene Tree for CCDC129 (if available)
TreeFam Gene Tree for CCDC129 (if available) |
Paralogs
for CCDC129 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCDC129 gene
- TESPA12 SSFA22
CCDC129 for paralogs About GeneDecksing
|
Genomic Variants
for CCDC129 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC129 (31553704 - 31698334 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for CCDC129
4 CNVs: 8553 64793 59404 94432 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC129 |
|
Disorders
/ Diseases
for CCDC129 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 CCDC129 for disorders About MalaCards
CCDC129 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: CCDC129 (1 document)
Export disorders for CCDC129 gene to outside databases
|
Publications
for CCDC129 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC129 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC129) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for CCDC129 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC129 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC129 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC129 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC129 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC129 gene:
Search GeneIP for patents involving CCDC129
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC129 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC129 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC129 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC129 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC129 | | OriGene 3'-UTR Clone for CCDC129 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC129 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC129 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC129 | | OriGene Custom Protein Services for CCDC129 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC129 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC129 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC129 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC129 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC129 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC129 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCDC129 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CCDC129 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC129 |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC129 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC129 |
|
|
|
|
